An antimetabolite of the antifolate type, Methotrexate is an chemotherapy drug and used for treating autoimmune diseases like psoriasis, rheumatoid arthritis. It causes life threatening side effects. Reference standards of Methotrexate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
2,4-Diamino-6-pteridinemethanol Hydrochloride Salt
Catalogue No.:PA 13 0280011
CAS :
Molecular Formula : C7H9ClN6O
Molecular Weight : 228.64
7-Methylpteridine-2,4-diamine
Catalogue No.:PA 13 0281010
Molecular Formula : C7H8N6
Molecular Weight : 176.18
4-Amino-N10-methylpteroic acid, APA
Catalogue No.:PA 13 0280051
Molecular Formula : C15H15N7O2
Molecular Weight : 325.33
Methotrexate
Catalogue No.:PA 13 28000
Molecular Formula : C20H22N8O5
Molecular Weight : 454.44
(2,4-Diaminopteridin-6-yl)methanol
Catalogue No.:PA 13 28010
Molecular Formula : C7H8N6O
Molecular Weight : 192.18
Aminopterin
Catalogue No.:PA 13 28020
Molecular Formula : C19H20N8O5
Molecular Weight : 440.41
Methopteridine
Catalogue No.:PA 13 28030
Molecular Formula : C20H21N7O6
Molecular Weight : 455.42
N10-Methyl Pteroic Acid
Catalogue No.:PA 13 28040
Molecular Formula : C15H14N6O3
Molecular Weight : 326.31
4-amino-N10-methylpteroic acid, APA Hydrochloride
Catalogue No.:PA 13 28050
Molecular Formula : C30H31ClN14O4
Molecular Weight : 687.12
(R)-Methotrexate
Catalogue No.:PA 13 28060
(2S)-2-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-4-(methoxycarbonyl)butanoic Acid
Catalogue No.:PA 13 28080
Molecular Formula : C21H24N8O5
Molecular Weight : 468.47
(4S)-4-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]amino]-4-(methoxycarbonyl)butanoic Acid
Catalogue No.:PA 13 28090
Methotrexate Dimethyl Ester
Catalogue No.:PA 13 28100
Molecular Formula : C22H26N8O5
Molecular Weight : 482.49
(2S)-2-[(4-Aminobenzoyl)amino]pentanedioic Acid
Catalogue No.:PA 13 28110
Molecular Formula : C12H14N2O5
Molecular Weight : 266.25
Methotrexate Triglutamate Trifluoroacetate
Catalogue No.:PA 13 28510
Molecular Formula : C30H36N10O11 xC2HF3O2
Molecular Weight : 712.67
Methotrexate Tetraglutamate Trifluoroacetate
Catalogue No.:PA 13 28520
Molecular Formula : C35H43N11O14 xC2HF3O2
Molecular Weight : 841.78
Methotrexate Pentaglutamate Trifluoroacetate
Catalogue No.:PA 13 28530
Molecular Formula : C40H50N12O17 xC2HF3O2
Molecular Weight : 970.9
Methopterine-d3
Catalogue No.:PA STI 061720
Molecular Formula : C20H18D3N7O6
Molecular Weight : 458.44
7-Hydroxy Methotrexate-d3
Catalogue No.:PA STI 049680
Molecular Formula : C20H19D3N8O6
Molecular Weight : 473.46
Methotrexate-d3
Catalogue No.:PA STI 059080
Molecular Formula : C20H19D3N8O5
Molecular Weight : 457.46
DL-Methotrexate-d3 Dipotassium Salt
Catalogue No.:PA STI 059090
Molecular Formula : C20H17D3K2N8O5
Molecular Weight : 533.64
Methotrexate Dimethylamide
Catalogue No.:PA 13 28540
Molecular Formula : C22H27N9O4
Molecular Weight : 481.52
(+/-)Amethopterin
Catalogue No.:PA 13 28550
N-(4-Aminobenzoyl)-D-glutamic acid
Catalogue No.:PA 13 28560
Catalogue No.:PA ICRS0345
Molecular Formula :
Molecular Weight : NA
Catalogue No.:PA IPIPRS 231 12
Methotrexate (JP 0148)
Catalogue No.:PA JP0148
Molecular Formula : NA
Methotrexate (M1000000)
Catalogue No.:PA EPM1000000
Methotrexate impurity D (M1000008)
Catalogue No.:PA EPM1000008
Methotrexate for peak identification (Y0000602)
Catalogue No.:PA EPY0000602
Methotrexate impurity C (Y0000663)
Catalogue No.:PA EPY0000663
Methotrexate impurity E (Y0000664)
Catalogue No.:PA EPY0000664
Methotrexate for system suitability (Y0001668)
Catalogue No.:PA EPY0001668
R-Methotrexate ((R)-2-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzamido)pentanedioic ac (1413988)
Catalogue No.:PA USP1413988
Methotrexate System Suitability Mixture (1413999)
Catalogue No.:PA USP1413999
Methotrexate (1414003)
Catalogue No.:PA USP1414003
Methotrexate Related Compound B ((S)-2-{4-[(2,4-diaminopteridin-6-yl)methylamino]benzamido}pentaned (1414025)
Catalogue No.:PA USP1414025
Methotrexate Related Compound C ((S)-2-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl](methyl) (1414036)
Catalogue No.:PA USP1414036
Methotrexate Related Compound E (4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzoic acid, h (1414058)
Catalogue No.:PA USP1414058
4-[[(2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoic Acid Methyl Ester
Catalogue No.:PA 13 28570
(2S)-2-[[4-(Methylamino)benzoyl]amino]pentanedioic Acid
Catalogue No.:PA 13 28120
Molecular Formula : C13H16N2O5
Molecular Weight : 280.28
(2S)-2-[[4-[[4-[[(2,4-Diaminopteridin-6-yl)methyl]methylamino]benzoyl]methylamino]benzoyl]amino]pentanedioic Acid
Catalogue No.:PA 13 28070
Molecular Formula : C28H29N9O6
Molecular Weight : 587.60
10-Deazaaminopterin
Catalogue No.:PA 13 0281000
Molecular Formula : C20H21N7O5
Molecular Weight : 439.43
7-Cyanomethotrexate Dimethyl Ester
Catalogue No.:PA 13 0281001
Molecular Formula : C23H25N9O5
Molecular Weight : 507.51
Methotrexate-d3 Dimethyl Ester
Catalogue No.:PA 13 0281002
Molecular Formula : C22H23D3N8O5
Molecular Weight : 485.52
7-Hydroxy Methotrexate
Catalogue No.:PA 13 0281003
Molecular Formula : C20H22N8O6
Molecular Weight : 470.45
(2,4-Diaminopteridin-7-yl)methanol
Catalogue No.:PA 13 0281004
2,4-Diaminopteridine
Catalogue No.:PA 13 0281005
Molecular Formula : C6H6N6
Molecular Weight : 162.16
6-Methylpteridine-2,4-diamine
Catalogue No.:PA 13 0281006
(4-Chlorobenzoyl)-L-glutamic Acid
Catalogue No.:PA 13 0281007
Molecular Formula : C12H12ClNO5
Molecular Weight : 285.68
Methotrexate System Suitability Mixture
Catalogue No.:PA 13 0281008
Aminopterin-α-hyrazide
Catalogue No.:PA 13 0281009
Molecular Formula : C19H22N10O4
Molecular Weight : 454.45
Diethyl (4-(methylamino)benzoyl)-L-glutamate
Catalogue No.:PA 13 0281011
Molecular Formula : C17H24N2O5
Molecular Weight : 336.39
Sodium (S)-2-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)-N-nitrosobenzamido)-2-methylpentanedioate
Catalogue No.:PA 13 0281012
Molecular Formula : C21H21N9Na2O6
Molecular Weight : 541.44
(4-(((2,4-Diaminopteridin-6-yl)methyl)(nitroso)amino)benzoyl)-L-glutamic Acid
Catalogue No.:PA 13 0281013
Molecular Formula : C19H19N9O6
Molecular Weight : 469.42
N-(4-(Methylamino)benzoyl)-N-nitroso-L-glutamic Acid
Catalogue No.:PA 13 0281014
Molecular Formula : C13H15N3O6
Molecular Weight : 309.28
(4-(Methyl(nitroso)amino)benzoyl)-L-glutamic Acid
Catalogue No.:PA 13 0281015
N-(4-(Methyl(nitroso)amino)benzoyl)-N-nitroso-L-glutamic Acid
Catalogue No.:PA 13 0281016
Molecular Formula : C13H14N4O7
Molecular Weight : 338.28
(4-(Methylamino)benzoyl)-D-glutamic Acid
Catalogue No.:PA 13 0281017
(2,4-Diaminopteridine-6,7-diyl)dimethanol
Catalogue No.:PA 13 0281018
Molecular Formula : C8H10N6O2
Molecular Weight : 222.21
(4-(((2,4-diaminopteridin-6-yl)methyl)amino)benzoyl)-L-glutamic acid hydrate
Catalogue No.:PA 13 0280021
Molecular Formula : C19H22N8O6
Diethyl (4-(methylamino)benzoyl)-D-glutamate
Catalogue No.:PA 13 0281019
Diethyl (4-(dimethylamino)benzoyl)-L-glutamate
Catalogue No.:PA 13 0281020
Molecular Formula : C18H26N2O5
Molecular Weight : 350.42
Diethyl (4-chlorobenzoyl)-L-glutamate
Catalogue No.:PA 13 0281021
Molecular Formula : C16H20ClNO5
Molecular Weight : 341.79
Diethyl (4-hydroxybenzoyl)-L-glutamate
Catalogue No.:PA 13 0281022
Molecular Formula : C16H21NO6
Molecular Weight : 323.35
(2S)-2-[[4-(Methylamino)benzoyl]amino]pentanedioic Acid Zinc Salt
Catalogue No.:PA 13 0280121
Molecular Formula : C13H14N2O5Zn
Molecular Weight : 343.64
Methotrexate Diethyl Ester
Catalogue No.:PA 13 0281024
Molecular Formula : C24H30N8O5
Molecular Weight : 510.56
(S)-5-Ethoxy-2-(4-(methylamino)benzamido)-5-oxopentanoic Acid
Catalogue No.:PA 13 0281025
Molecular Formula : C15H20N2O5
Molecular Weight : 308.33
(S)-5-Ethoxy-4-(4-(methylamino)benzamido)-5-oxopentanoic Acid
Catalogue No.:PA 13 0281026
(S)-2-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-ethoxy-5-oxopentanoic Acid
Catalogue No.:PA 13 0281027
Molecular Weight : 482.5
(S)-4-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-ethoxy-5-oxopentanoic Acid
Catalogue No.:PA 13 0281028
Methotrexate (IPRS/83/18)
Catalogue No.:PA IPRS 83 18
N-(4,6-Diaminopyrimidin-2-yl)nitrous Amide
Catalogue No.:PA 13 0281029
Molecular Formula : C4H6N6O
Molecular Weight : 154.13
Diethyl (3-(methylamino)benzoyl)-L-glutamate
Catalogue No.:PA 13 0281030
Diethyl (2-(methylamino)benzoyl)-L-glutamate
Catalogue No.:PA 13 0281031
(2S)-2-[[4-(Methylamino)benzoyl]amino]pentanedioic Acid Disodium Salt
Catalogue No.:PA 13 0280122
Molecular Formula : C13H14N2Na2O5
Molecular Weight : 324.24
N-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-N-nitroso-L-glutamic Acid
Catalogue No.:PA 13 0281032
Molecular Formula : C20H21N9O6
Molecular Weight : 483.45
N-(4-(((2,4-Diaminopteridin-6-yl)methyl)(nitroso)amino)benzoyl)-N-formyl-L-glutamic Acid
Catalogue No.:PA 13 0281033
Molecular Formula : C20H19N9O7
Molecular Weight : 497.43
Diethyl (4-(methyl(nitroso)amino)benzoyl)-D-glutamate
Catalogue No.:PA 13 0281034
Molecular Formula : C17H23N3O6
Molecular Weight : 365.39
Diethyl N-(4-(methylamino)benzoyl)-N-nitroso-D-glutamate
Catalogue No.:PA 13 0281035
Diethyl N-(4-(methyl(nitroso)amino)benzoyl)-N-nitroso-D-glutamate
Catalogue No.:PA 13 0281036
Molecular Formula : C17H22N4O7
Molecular Weight : 394.38
N-(4-(((2,4-Diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-N-nitroso-D-glutamic Acid
Catalogue No.:PA 13 0281037
Diethyl N-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzoyl)-N-nitroso-L-glutamate
Catalogue No.:PA 13 0281038
Molecular Formula : C24H29N9O6
Molecular Weight : 539.55
(2S)-2-[(4-Aminobenzoyl)amino]pentanedioic Acid Monosodium Salt
Catalogue No.:PA 13 0280111
Molecular Formula : C12H14N2NaO5
Molecular Weight : 289.24
(R)-Methotrexate Disodium
Catalogue No.:PA 13 0280061
Molecular Formula : C20H20N8Na2O5
Molecular Weight : 498.41
Dimethyl (4-(methylamino)benzoyl)-L-glutamate
Catalogue No.:PA 13 0281039
(S)-5-Methoxy-4-(4-(methylamino)benzamido)-5-oxopentanoic Acid
Catalogue No.:PA 13 0281040
Molecular Formula : C14H18N2O5
Molecular Weight : 294.31
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