Methotrexate System Suitability Mixture

NA

(S)-2-(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzamido)pentanedioic acid and (S)-Dimethyl-2-(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)amino}benzamido) pentanedioate hydrochloride and (S)-4-(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzamido)-5-methoxy-5-oxopentanoic acid and (S)-2-(4-{[(2,4-Diaminopteridin-6-yl)methyl](methyl)amino}benzamido)-5-methoxy-5-oxopentanoic acid; Mixture of Methotrexate (~9%), Methotrexate Related Compound H (~27%), Methotrexate RelatedCompound I (~7%) and Methotrexate Dimethylester Hydrochloride (~55%) (USP);