| Catalogue number: | PA 13 0281009 |
| Chemical name: | Aminopterin-α-hyrazide |
CAS Number: |
118359-33-4 |
| Category: | impurities,metabolites,pharmaceutical standards,intermediates,Fine Chemicals |
| Synonyms: | N5-Amino-N2-(4-((2,4-diaminopteridin-6-yl)(methyl)amino)benzoyl)-L-glutamine; |
| Molecular form: | C19H22N10O4 |
| Appearance: | NA |
| Mol. Weight: | 454.45 |
| Storage: | 2-8°C Refrigerator |
| Shipping Conditions: | Ambient |
| Applications: | Aminopterin-α-hyrazide, is derivative of Aminopterin (A628850), which is a folic acid antagonist. Its actively transported into cells by thefolate transporter. In the cell, its converted to a high molecular weight polyglutamate metabolite by folylpolyglutamate synthase, that, in turn, binds to dihydrofolate reductase and inhibits its activity. |
Aminopterin-α-hyrazide
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