Mertansine is a thiol-containing maytansinoid which is used for therapeutic purposes is attached to a monoclonal antibody through reaction of the thiol group with a linker structure to create an antibody-drug conjugate. It is also called DM1. Reference standards of Mertansine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Mertansine - API Standards [catalogue_number] => PA 40 42000 [category_ids] => ,79,80,71,78,70,82,88, [chemical_name] => [weight] => 738.29 [form] => C35H48ClN3O10S [cas] => 139504-50-0 [pslug] => 139504-50-0-mertansine-api-pa4042000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 40 42000
CAS :
Molecular Formula : C35H48ClN3O10S
Molecular Weight : 738.29
stdClass Object ( [pname] => 2,5-Dioxopyrrolidin-1-yl 4-((3-((3-(((2S)-1-(((14S,16S,33S,2R,4R,10E,12Z,14R)-86-chloro-14-hydroxy-85,14-dimethoxy-33,2,7,10-tetramethyl-12,6-dioxo-7-aza-1(6,4)-oxazinana-3(2,3)-oxirana-8(1,3)-benzenacyclotetradecaphane-10,12-dien-4-yl)oxy)-1-oxopropan-2-yl)(methyl)amino)-3-oxopropyl)thio)-2,5-dioxopyrrolidin-1-yl)methyl)cyclohexane-1-carboxylate [catalogue_number] => PA 40 42510 [category_ids] => ,78,70,82,80,75, [chemical_name] => [weight] => 1072.61 [form] => C51H66ClN5O16S [cas] => 1228105-51-8 [pslug] => 1228105-51-8-2-5-dioxopyrrolidin-1-yl-4-3-3-2s-1-14s-16s-33s-2r-4r-10e-12z-14r-86-chloro-14-hydroxy-85-14-dimethoxy-33-2-7-10-tetramethyl-12-6-dioxo-7-aza-1-6-4-oxazinana-3-2-3-oxirana-8-1-3-benzenacyclotetradecaphane-10-12-dien-4-yl-oxy-1-oxopropan-2-yl-methyl-amino-3-oxopropyl-thio-2-5-dioxopyrrolidin-1-yl-methyl-cyclohexane-1-carboxylate-pa4042510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 40 42510
Molecular Formula : C51H66ClN5O16S
Molecular Weight : 1072.61
stdClass Object ( [pname] => Maytansine, N2′-deacetyl-N2′-(3-mercapto-1-oxopropyl)-, (2′R) [catalogue_number] => PA 40 0421000 [category_ids] => ,78,70,82,88, [chemical_name] => [weight] => 738.29 [form] => C35H48ClN3O10S [cas] => 936481-22-0 [pslug] => 936481-22-0-maytansine- n2-deacetyl-n2-3-mercapto-1-oxopropyl-2r-pa400421000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 40 0421000
stdClass Object ( [pname] => DM1-SMCC [catalogue_number] => PA 40 0421001 [category_ids] => ,79,80,71,78,70,82, [chemical_name] => [weight] => 1072.62 [form] => C51H66ClN5O16S [cas] => 1613362-80-3 [pslug] => 1613362-80-3-dm1-smcc-pa400421001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 40 0421001
Molecular Weight : 1072.62
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