Voclosporin is more potent and less toxic than currently available treatments within the drug class of calcineurin inhibitors. Voclosporin is a novel cyclosporine analog and immunosuppressive compound currently being investigated for the treatment of psoriasis and for the prevention of organ rejection in kidney transplant patients. Reference standards of Voclosporin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Voclosporin-d4
Catalogue No.:PA STI 087320
CAS :
Molecular Formula : C63H107D4N11O12
Molecular Weight : 1218.65
Voclosporin
Catalogue No.:PA 22 0900000
Molecular Formula : C63H111N11O12
Molecular Weight : 1214.65
Voclosporin Z-Isomer
Catalogue No.:PA 22 0901000
Cyclosporin A, 6-[(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6,8-nonadienoic Acid]
Catalogue No.:PA 22 0901001
Molecular Formula : C65H113N11O13
Molecular Weight : 1256.68
Voclosporin V
Catalogue No.:PA 22 0901002
Molecular Formula : C64H113N11O12
Molecular Weight : 1228.67
Dehydro Voclosporin
Catalogue No.:PA 22 0901003
Molecular Formula : C63H109N11O11
Molecular Weight : 1196.63
(3S,6S,9S,12S,15S,18R,21S,24S,27S,30S)-3-Ethyl-6-((1R,2R,E)-1-hydroxy-2-methylhepta-4,6-dien-1-yl)-12,15,24,30-tetraisobutyl-9,27-diisopropyl-1,7,10,13,16,18,21,25,31-nonamethyl-4-nitroso-1,4,7,10,13,16,19,22,25,28,31-undecaazacyclotritriacontan-2,5,8,11,14,17,20,23,26,29,32-undecaone
Catalogue No.:PA PEP 001187
Molecular Formula : C63H110N12O13
Molecular Weight : 1243.64
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