Voclosporin-d4

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Catalogue number:	PA STI 087320
Chemical name:	Voclosporin-d4
CAS Number:	NA
Category:	intermediates,pharmaceutical standards,Fine Chemicals,stable isotopes,peptides
Synonyms:	6-[(2S,3R,4R,6E)-3-Hydroxy-4-methyl-2-(methylamino)-6,8-nonadienoic acid]cyclosporin A-d4; ISATX 247-d4; R 1524-d4; trans-ISA 247-d4;
Molecular form:	C₆₃H₁₀₇D₄N₁₁O₁₂
Appearance:	NA
Mol. Weight:	1218.65
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Labelled Voclosporin. A new agent for the treatment of noninfectious uveitis. Uveitis is an inflammatory, putative Th1-mediated autoimmune disease that affects various parts of the eye and is a leading cause of visual loss. Voclosporin, a rationally designed novel calcineurin inhibitor, exhibits a favorable safety profile, a strong correlation between pharmacokinetic and pharmacodynamic response, and a wide therapeutic window. Immunosuppressant.