Bortezomib was approved for medical use in the United States in 2003 and in Europe in 2004. Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma.. Reference standards of Bortezomib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
Bortezomib
Catalogue No.:PA 02 79000
CAS :
Molecular Formula : C19H25BN4O4
Molecular Weight : 384.24
Bortezomib (1S,2R)-Isomer
Catalogue No.:PA 02 79530
2-Methylpropylboronic Acid
Catalogue No.:PA 02 79760
Molecular Formula : C4H11BO2
Molecular Weight : 101.94
N-(2-Pyrazinylcarbonyl)-D-phenylalanine
Catalogue No.:PA 02 79770
Molecular Formula : C14H13N3O3
Molecular Weight : 271.28
Bortezomib Amide Impurity
Catalogue No.:PA 02 0791001
Molecular Formula : C14H14N4O2
Molecular Weight : 270.29
Bortezomib Acid Analog
Catalogue No.:PA 02 0791002
Molecular Weight : 271.27
Bortezomib Diastereomer (R,R)
Catalogue No.:PA 02 0791004
Bortezomib Diastereomer (S,S)
Catalogue No.:PA 02 0791005
(S,R)-Bortezomib Hydroxyisopentyl Amide Analog
Catalogue No.:PA 02 0791006
Molecular Formula : C19H24N4O3
Molecular Weight : 356.42
(S,S)-Bortezomib Hydroxyisopentyl Amide Analog
Catalogue No.:PA 02 0791008
Pyrazine-2,3-dicarboxylic acid
Catalogue No.:PA 02 0791020
Molecular Formula : C6H4N2O4
Molecular Weight : 168.11
Bortezomib Acid Analog (Mixture)
Catalogue No.:PA 02 0791039
Bortezomib Amide analog (R-Isomer)
Catalogue No.:PA 02 0791040
1-Bromo-2-methylpropane
Catalogue No.:PA 02 79510
Molecular Formula : C4H9Br
Molecular Weight : 137.02
(1S)-(1S,2S,3R,5S)-Pinanediol-1-ammoniumtrifluoroacetate-3-methylbutane-1-boronate
Catalogue No.:PA 02 79520
Molecular Formula : C17H29BF3NO4
Molecular Weight : 379.22
N-(1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79540
Bortezomib Amide analog (Mixture of isomers)
Catalogue No.:PA 02 79550
N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
Catalogue No.:PA 02 79560
Molecular Formula : C19H24N4O2
Molecular Weight : 340.42
(R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic Acid
Catalogue No.:PA 02 79570
Molecular Formula : C10H16BN3O3
Molecular Weight : 237.06
N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79580
(4-Hydroxy-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic Acid
Catalogue No.:PA 02 79590
Molecular Formula : C18H23BN4O5
Molecular Weight : 386.21
N-(1-((1-(3a,5-Dimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79600
Molecular Formula : C28H37BN4O4
Molecular Weight : 504.43
(R)-2-(N-Methylpyrazine-2-carboxamido)-3-phenylpropanoic Acid
Catalogue No.:PA 02 79610
Molecular Formula : C15H15N3O3
Molecular Weight : 285.3
N-((2S)-1-((1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79620
3-Hydroxy Bortezomib
Catalogue No.:PA 02 79630
Molecular Formula : C19H25BN4O5
Molecular Weight : 400.24
(S)-N-(1-Formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79640
Molecular Formula : C15H14N4O3
Molecular Weight : 298.3
(S)-N-[1-(3-Hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl]pyrazine-2-carboxamide
Catalogue No.:PA 02 79650
Molecular Formula : C19H22N4O4
Molecular Weight : 370.4
(R)-Hydroperoxy Des(boric Acid) Bortezomib
Catalogue No.:PA 02 79660
Molecular Formula : C19H24N4O4
Molecular Weight : 372.42
(S)-Hydroperoxy Des(boric Acid) Bortezomib
Catalogue No.:PA 02 79670
Molecular Weight : 372.43
((R)-3-Methyl-1-((S)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic Acid
Catalogue No.:PA 02 79680
Molecular Formula : C28H34BN5O5
Molecular Weight : 531.41
Bortezomib ((1R,2S)-Bortezomib)
Catalogue No.:PA 02 79690
Molecular Formula : C57H69B3N12O9
Molecular Weight : 1098.67
(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate
Catalogue No.:PA 02 79700
Molecular Formula : C29H39BN4O4
Molecular Weight : 518.46
(R,R)-Hydroxy Des(boric Acid) Bortezomib
Catalogue No.:PA 02 79710
Bortezomib-D8 (Major)
Catalogue No.:PA STI 014210
Molecular Formula : C19H17D8BN4O4
Molecular Weight : 392.29
(1R,2R)-Bortezomib-d5
Catalogue No.:PA STI 014220
Molecular Formula : C19H20D5BN4O4
Molecular Weight : 389.27
(1S,2R)-Bortezomib-d5
Catalogue No.:PA STI 014230
(1S,2S)-Bortezomib-d5
Catalogue No.:PA STI 014240
(1R,2S)-Bortezomib-d5
Catalogue No.:PA STI 014241
(1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methylbutane-1-boronate-d8
Catalogue No.:PA STI 073740
Molecular Formula : C29H31D8BN4O4
Molecular Weight : 526.50
Bortezomib L-Phenylalanyl Analog
Catalogue No.:PA 02 79720
Molecular Weight : 531.42
N-((S)-1-(((R)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide compound with N-((S)-1-(((S)-1-hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide (1:1)
Catalogue No.:PA 02 79730
N-((S)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide compound with N-((S)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide (1:1)
Catalogue No.:PA 02 79740
Molecular Weight : 356.43
(αR)-(1S,2S,3R,5S)-Pinanediol-1-amino-3-methylbutane-1-boronate Trifluoroacetic Acid Salt
Catalogue No.:PA 02 79750
Molecular Weight : 379.23
N-((2S)-1-(((1R)-1-(2-Hydroxypropoxy)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79780
Molecular Formula : C22H30N4O4
Molecular Weight : 414.51
N-((2S)-1-(((1S)-1-(2-Hydroxypropoxy)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79790
N-((2R)-1-(((1S)-1-(2-Hydroxypropoxy)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79800
N-((2R)-1-(((1R)-1-(2-Hydroxypropoxy)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79810
(αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride
Catalogue No.:PA 02 79840
Molecular Formula : C23H36BClN2O3
Molecular Weight : 434.81
(S,E)-N-(1-((3-Methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 79820
Molecular Formula : C19H22N4O2
Molecular Weight : 338.41
Des-pyrazinecarboxaldehyde Bortezomib
Catalogue No.:PA 02 79830
Molecular Formula : C14H23BN2O3
Molecular Weight : 278.16
(Pyrazine-2-carbonyl)-L-phenylalanyl-L-phenylalanine
Catalogue No.:PA 02 0791000
Molecular Formula : C23H22N4O4
Molecular Weight : 418.45
Desisobutyl-n-butyl Bortezomib
Catalogue No.:PA 02 0791003
Bortezomib Acid Methyl Ester
Catalogue No.:PA 02 0791007
Pyrazinecarboxylic Acid Imidazolide
Catalogue No.:PA 02 0791009
Molecular Formula : C8H6N4O
Molecular Weight : 174.16
N-(Trimethylsilyl)-L-phenylalanine trimethylsilyl Ester
Catalogue No.:PA 02 0791010
Molecular Formula : C15H27NO2Si2
Molecular Weight : 309.56
N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-carbamic acid 1,1-dimethylethyl ester
Catalogue No.:PA 02 0791011
Molecular Formula : C29H45BN2O5
Molecular Weight : 512.5
N-((S)-1-(((R)-1-((R)-2-Hydroxypropoxy)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791012
N-((S)-1-(((R)-1-((S)-2-Hydroxypropoxy)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791013
(S)-N-(1-(3-Methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791014
Molecular Formula : C19H22N4O3
Molecular Weight : 354.41
(R)-1-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pentan-1-amine hydrochloride
Catalogue No.:PA 02 0791015
Molecular Formula : C11H25BClNO2
Molecular Weight : 249.59
((S)-3-Hydroxy-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
Catalogue No.:PA 02 0791016
(3aS,4S,6S,7aR)-2-((S)-1-Chloro-2-methylpropyl)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole
Catalogue No.:PA 02 0791017
Molecular Formula : C14H24BClO2
Molecular Weight : 270.6
(R)-2-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)propan-1-amine 2,2,2-trifluoroacetate
Catalogue No.:PA 02 0791018
Molecular Formula : C16H27BF3NO4
Molecular Weight : 365.2
(3aR,4R,6R,7aS)-2-((R)-1-Chloro-2-methylpropyl)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole
Catalogue No.:PA 02 0791019
((R)-3-Methyl-1-((R)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic acid
Catalogue No.:PA 02 0791021
N-((R)-1-(((R)-3-Methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791022
Molecular Weight : 518.47
Methyl (pyrazine-2-carbonyl)-D-phenylalaninate
Catalogue No.:PA 02 0791023
N-(1-((3-Methyl-1-(3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791024
N-(Pyrazine-2-yl-carbonyl)-L-phenylalanine Magnesium Salt
Catalogue No.:PA 02 0791025
Molecular Formula : C28H24MgN6O6
Molecular Weight : 564.84
Tert-butyl (S)-(1-(isopentylamino)-1-oxo-3-phenylpropan-2-yl)carbamate
Catalogue No.:PA 02 0791026
Molecular Formula : C19H30N2O3
Molecular Weight : 334.46
Tert-butyl (1-(isopentylamino)-1-oxo-3-phenylpropan-2-yl)carbamate
Catalogue No.:PA 02 0791027
(3aS,4S,6S,7aR)-2-Isobutyl-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole
Catalogue No.:PA 02 0791028
Molecular Formula : C14H25BO2
Molecular Weight : 236.16
N-(Pyrazine-2-yl-carbonyl)-L-phenylalanine Sodium Salt
Catalogue No.:PA 02 0791029
Molecular Formula : C14H12N3NaO3
Molecular Weight : 293.26
1,1,1-Trimethyl-N-((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)-N-(trimethylsilyl)silanamine
Catalogue No.:PA 02 0791030
Molecular Formula : C21H44BNO2Si2
Molecular Weight : 409.57
N-((R)-1-(((S)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791031
(1S,2S,3R,5S)-2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol
Catalogue No.:PA 02 0791033
Molecular Formula : C10H18O2
Molecular Weight : 170.25
1,1,1-Trimethyl-N-((R)-2-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)propyl)-N-(trimethylsilyl)silanamine
Catalogue No.:PA 02 0791032
Molecular Formula : C20H42BNO2Si2
Molecular Weight : 395.54
(3aS,4S,6S,7aR)-2-((S)-1-Chloro-3-methylbutyl)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]Dioxaborole
Catalogue No.:PA 02 0791034
Molecular Formula : C15H26BClO2
Molecular Weight : 284.63
Bortezomib (R,R-Isomer)
Catalogue No.:PA 02 0791035
Molecular Weight : 1098.68
Bortezomib (R,S-Isomer)
Catalogue No.:PA 02 0791036
Bortezomib (S,S-Isomer)
Catalogue No.:PA 02 0791037
N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791038
Pyrazine-2-carbonyl Chloride
Catalogue No.:PAI 02 079001
Molecular Formula : C5H3ClN2O
Molecular Weight : 142.54
(1-((S)-3-Phenyl-2-(pyrazine-2-carboxamido)propanamido)pentyl)boronic Acid
Catalogue No.:PA 02 0791041
N-(1-((1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791042
rel-(R)-3-Methyl-1-((3aS,4R,6R,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate
Catalogue No.:PA 02 0791043
Bortezomib Mannitol
Catalogue No.:PA 02 0791044
Molecular Formula : C25H35BN4O8
Molecular Weight : 530.39
N-((R)-1-(((R)-1-Hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
Catalogue No.:PA 02 0791045
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