Apatinib is a novel, small molecule, selective vascular endothelial growth factor receptor-2 tyrosine kinase inhibitor and is the second anti-angiogenic drug to be approved in China for the treatment of advanced or metastatic gastric cancer.Reference standards of Apatinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
Apatinib-d8 Hydrochloride
Catalogue No.:PA STI 008150
CAS :
Molecular Formula : C24H16D8ClN5O
Molecular Weight : 441.98
Apatinib-d8 25-N-Oxide Hydrochloride
Catalogue No.:PA STI 008160
Molecular Formula : C24H16D8ClN5O2
Molecular Weight : 457.98
rac cis-3-Hydroxy Apatinib-d4 Hydrochloride
Catalogue No.:PA STI 047290
Molecular Formula : C24H20D4ClN5O2
Molecular Weight : 453.96
rac trans-3-Hydroxy Apatinib-d4 Hydrochloride
Catalogue No.:PA STI 047300
rac cis-3-Hydroxy Apatinib-d4 3-O-β-D-Glucuronide
Catalogue No.:PA STI 047310
Molecular Formula : C30H27D4N5O8
Molecular Weight : 593.62
Apatinib
Catalogue No.:PA 01 3640000
Molecular Formula : C24H23N5O
Molecular Weight : 397.48
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