Name: Apatinib-d8 Hydrochloride
Brand: Pharmaffliates
Rating: 4.50 (5 reviews)

Catalogue number:	PA STI 008150
Chemical name:	Apatinib-d8 Hydrochloride
CAS Number:	2468771-44-8
Alternate CAS Number:	2468771-43-7 (Apatinib-d8)
Category:	aromatics,heterocycles,pharmaceutical standards,intermediates,Fine Chemicals,tyrosine kinase inhibitors,stable isotopes
Synonyms:	N-(4-(1-Cyanocyclopentyl-2,2,3,3,4,4,5,5-d8)phenyl)-2-((pyridin-4-ylmethyl)amino)nicotinamide; YN968D1-d8 Hydrochloride;
Molecular form:	C₂₄H₁₆D₈ClN₅O
Appearance:	NA
Mol. Weight:	441.98
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Labelled Apatinib. Apatinib is an orally available, small molecule multitargeted tyrosine kinase inhibitor. Apatinib selectively inhibits the vascular endothelial growth factor receptor-2 (VEGFR2). Apatinib functions by inhibiting VEGF-mediated endothelial cell migration and proliferation thus blocking new blood vessel formation in tumor tissue. Recent studies have shown that Apatinib enhances the efficacy of conventional chemotherapeutical drugs in side population (SP) cells and ABCB1-overexpressing leukemia cells.

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Apatinib-d8 Hydrochloride

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