cevimeline

Pharmaceutical standards - Cevimeline is used in the treatment of dry mouth and especially associated with Sjögren's syndrome. It is a parasympathomimetic and muscarinic agonist, with particular effect on M1 and M3 receptors.. Reference standards of Cevimeline API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Cevimeline
    [catalogue_number] => PA 56 31000
    [category_ids] => ,71,93,78,70,82,
    [chemical_name] => 
    [weight] => 199.30
    [form] => C10H17NOS
    [cas] => 107233-08-9
    [pslug] => 107233-08-9-cevimeline-api-pa5631000
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PA 56 31000
PA 56 31000

Cevimeline

  • Catalogue No.:PA 56 31000

  • CAS :

    107233-08-9

  • Molecular Formula : C10H17NOS

  • Molecular Weight : 199.30

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stdClass Object
(
    [pname] => Cevimeline-d4 Hydrochloride Salt
    [catalogue_number] => PA STI 018790
    [category_ids] => ,70,71,78,82,93,98,
    [chemical_name] => 
    [weight] => 239.8
    [form] => C10H14D4ClNOS
    [cas] => NA
    [pslug] => cevimeline-d4-hydrochloride-salt-pasti018790
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PA STI 018790
PA STI 018790

Cevimeline-d4 Hydrochloride Salt

  • Catalogue No.:PA STI 018790

  • CAS :

    NA

  • Molecular Formula : C10H14D4ClNOS

  • Molecular Weight : 239.8

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stdClass Object
(
    [pname] => Cevimeline Thiol Impurity
    [catalogue_number] => PA 56 0311000
    [category_ids] => ,82,78,76,75,
    [chemical_name] => 
    [weight] => 173.27
    [form] => C8H15NOS
    [cas] => 107220-26-8
    [pslug] => 107220-26-8-3-cevimeline-thiol-impurity-pa560311000
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PA 56 0311000
PA 56 0311000

Cevimeline Thiol Impurity

  • Catalogue No.:PA 56 0311000

  • CAS :

    107220-26-8

  • Molecular Formula : C8H15NOS

  • Molecular Weight : 173.27

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stdClass Object
(
    [pname] => (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide
    [catalogue_number] => PA 56 0311001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 215.31
    [form] => C10H17NO2S
    [cas] => 124751-37-7
    [pslug] => 124751-37-7-2r-2r-2-methyl-4-azaspiro-bicyclo-2-2-2-octane-2-5-1-3-oxathiolane-3-oxide-pa560311001
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PA 56 0311001
PA 56 0311001

(2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3'-oxide

  • Catalogue No.:PA 56 0311001

  • CAS :

    124751-37-7

  • Molecular Formula : C10H17NO2S

  • Molecular Weight : 215.31

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stdClass Object
(
    [pname] => Cevimeline Diol
    [catalogue_number] => PA 56 0311002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 157.21
    [form] => C8H15NO2
    [cas] => NA
    [pslug] => cevimeline-diol-pa560311002
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PA 56 0311002
PA 56 0311002

Cevimeline Diol

  • Catalogue No.:PA 56 0311002

  • CAS :

    NA

  • Molecular Formula : C8H15NO2

  • Molecular Weight : 157.21

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stdClass Object
(
    [pname] => Cevimeline trans-Isomer Dihydrochloride Monohydrate
    [catalogue_number] => PA 56 0311003
    [category_ids] => ,93,82,78,71,70,
    [chemical_name] => 
    [weight] => 489.56
    [form] => C20H38Cl2N2O3S2
    [cas] => 1462862-74-3
    [pslug] => 1462862-74-3-cevimeline-trans-isomer-dihydrochloride-monohydrate-pa560311003
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PA 56 0311003
PA 56 0311003

Cevimeline trans-Isomer Dihydrochloride Monohydrate

  • Catalogue No.:PA 56 0311003

  • CAS :

    1462862-74-3

  • Molecular Formula : C20H38Cl2N2O3S2

  • Molecular Weight : 489.56

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stdClass Object
(
    [pname] => (E)-1,4'-Diaza[2,2'-bi(bicyclo[2.2.2]octanylidene)]-3-one--(Z)-1,4'-diaza[2,2'-bi(bicyclo[2.2.2]octanylidene)]-3-one (1/1)
    [catalogue_number] => PA 56 0311004
    [category_ids] => ,71,93,78,82,
    [chemical_name] => 
    [weight] => 232.3
    [form] => C14H20N2O
    [cas] => NA
    [pslug] => e-1-4-diaza-2-2-bi-bicyclo-2-2-2-octanylidene-3-one-z-1-4-diaza-2-2-bi-bicyclo-2-2-2-octanylidene-3-one-1-1-pa560311004
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PA 56 0311004
PA 56 0311004

(E)-1,4'-Diaza[2,2'-bi(bicyclo[2.2.2]octanylidene)]-3-one--(Z)-1,4'-diaza[2,2'-bi(bicyclo[2.2.2]octanylidene)]-3-one (1/1)

  • Catalogue No.:PA 56 0311004

  • CAS :

    NA

  • Molecular Formula : C14H20N2O

  • Molecular Weight : 232.3

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Details 
stdClass Object
(
    [pname] => 3,3'-(Thiobis(methylene))bis(quinuclidin-3-ol)
    [catalogue_number] => PA 56 0311005
    [category_ids] => ,71,93,78,82,
    [chemical_name] => 
    [weight] => 312.47
    [form] => C16H28N2O2S
    [cas] => 1434122-45-8
    [pslug] => 1434122-45-8-3-3-thiobis-methylene-bis-quinuclidin-3-ol-pa560311005
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PA 56 0311005
PA 56 0311005

3,3'-(Thiobis(methylene))bis(quinuclidin-3-ol)

  • Catalogue No.:PA 56 0311005

  • CAS :

    1434122-45-8

  • Molecular Formula : C16H28N2O2S

  • Molecular Weight : 312.47

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stdClass Object
(
    [pname] => 3,3'-(Disulfanediylbis(methylene))bis(quinuclidin-3-ol)
    [catalogue_number] => PA 56 0311006
    [category_ids] => ,71,93,78,82,
    [chemical_name] => 
    [weight] => 344.53
    [form] => C16H28N2O2S2
    [cas] => 1434122-43-6
    [pslug] => 1434122-43-6-3-3-disulfanediylbis-methylene-bis-quinuclidin-3-ol-pa560311006
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PA 56 0311006
PA 56 0311006

3,3'-(Disulfanediylbis(methylene))bis(quinuclidin-3-ol)

  • Catalogue No.:PA 56 0311006

  • CAS :

    1434122-43-6

  • Molecular Formula : C16H28N2O2S2

  • Molecular Weight : 344.53

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Details 
stdClass Object
(
    [pname] => (2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3',3'-dioxide
    [catalogue_number] => PA 56 0311007
    [category_ids] => ,71,93,78,70,82,
    [chemical_name] => 
    [weight] => 231.31
    [form] => C10H17NO3S
    [cas] => NA
    [pslug] => 2r-2r-2-methyl-4-azaspiro-bicyclo-2-2-2-octane-2-5-1-3-oxathiolane-3-3-dioxide-pa560311007
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PA 56 0311007
PA 56 0311007

(2R,2'R)-2'-Methyl-4-azaspiro[bicyclo[2.2.2]octane-2,5'-[1,3]oxathiolane] 3',3'-dioxide

  • Catalogue No.:PA 56 0311007

  • CAS :

    NA

  • Molecular Formula : C10H17NO3S

  • Molecular Weight : 231.31

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Details 
stdClass Object
(
    [pname] => (Disulfanediylbis(methylene))bis(quinuclidine-3,3-diyl) Diacetate
    [catalogue_number] => PA 56 0311008
    [category_ids] => ,71,93,78,70,82,
    [chemical_name] => 
    [weight] => 428.61
    [form] => C20H32N2O4S2
    [cas] => NA
    [pslug] => disulfanediylbis-methylene-bis-quinuclidine-3-3-diyl-diacetate-pa560311008
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PA 56 0311008
PA 56 0311008

(Disulfanediylbis(methylene))bis(quinuclidine-3,3-diyl) Diacetate

  • Catalogue No.:PA 56 0311008

  • CAS :

    NA

  • Molecular Formula : C20H32N2O4S2

  • Molecular Weight : 428.61

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stdClass Object
(
    [pname] => 3-((((3-Hydroxyquinuclidin-3-yl)methyl)disulfanyl)methyl)quinuclidin-3-yl Acetate
    [catalogue_number] => PA 56 0311009
    [category_ids] => ,71,93,78,70,82,
    [chemical_name] => 
    [weight] => 386.57
    [form] => C18H30N2O3S2
    [cas] => NA
    [pslug] => 3-3-hydroxyquinuclidin-3-yl-methyl-disulfanyl-methyl-quinuclidin-3-yl-acetate-pa560311009
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PA 56 0311009
PA 56 0311009

3-((((3-Hydroxyquinuclidin-3-yl)methyl)disulfanyl)methyl)quinuclidin-3-yl Acetate

  • Catalogue No.:PA 56 0311009

  • CAS :

    NA

  • Molecular Formula : C18H30N2O3S2

  • Molecular Weight : 386.57

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Details 
stdClass Object
(
    [pname] => 3,3'-((Ethane-1,1-diylbis(sulfanediyl))bis(methylene))bis(quinuclidin-3-ol)
    [catalogue_number] => PA 56 0311010
    [category_ids] => ,71,93,78,70,82,
    [chemical_name] => 
    [weight] => 372.59
    [form] => C18H32N2O2S2
    [cas] => NA
    [pslug] => 3-3-ethane-1-1-diylbis-sulfanediyl-bis-methylene-bis-quinuclidin-3-ol-pa560311010
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PA 56 0311010
PA 56 0311010

3,3'-((Ethane-1,1-diylbis(sulfanediyl))bis(methylene))bis(quinuclidin-3-ol)

  • Catalogue No.:PA 56 0311010

  • CAS :

    NA

  • Molecular Formula : C18H32N2O2S2

  • Molecular Weight : 372.59

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Details 
stdClass Object
(
    [pname] => Cevimeline trans-Isomer
    [catalogue_number] => PA 56 0311011
    [category_ids] => ,71,93,78,70,82,
    [chemical_name] => 
    [weight] => 199.31
    [form] => C10H17NOS
    [cas] => 107220-27-9
    [pslug] => 107220-27-9-cevimeline-trans-isomer-pa560311011
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PA 56 0311011
PA 56 0311011

Cevimeline trans-Isomer

  • Catalogue No.:PA 56 0311011

  • CAS :

    107220-27-9

  • Molecular Formula : C10H17NOS

  • Molecular Weight : 199.31

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