nebivolol

Heterocycles - A cardioselective β1 receptor blocker, Nebivolol is used for the treatment of hyertension. It works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This lowers the heart rate and blood pressure. Reference standards of Nebivolol API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Nebivolol
    [catalogue_number] => PA 14 15000
    [category_ids] => ,69,70,71,78,82,
    [chemical_name] => 
    [weight] => 405.43
    [form] => C22H25F2NO4
    [cas] => 118457-14-0
    [pslug] => 118457-14-0-nebivolol-api-pa1415000
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PA 14 15000
PA 14 15000

Nebivolol


  • Catalogue No.:PA 14 15000

  • CAS :

    118457-14-0

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.43

stdClass Object
(
    [pname] => Nebivolol Hydrochloride - Impurity C
    [catalogue_number] => PA 14 15510
    [category_ids] => ,78,70,82,71,
    [chemical_name] => 
    [weight] => 495.56
    [form] => C29H31F2NO4
    [cas] => 929706-85-4
    [pslug] => 929706-85-4-nebivolol-hydrochloride-impurity-c-pa1415510
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PA 14 15510
PA 14 15510

Nebivolol Hydrochloride - Impurity C


  • Catalogue No.:PA 14 15510

  • CAS :

    929706-85-4

  • Molecular Formula : C29H31F2NO4

  • Molecular Weight : 495.56

stdClass Object
(
    [pname] => (SR,RR) Nebivolol
    [catalogue_number] => PA 14 15530
    [category_ids] => ,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 441.9
    [form] => C22H26ClF2NO4
    [cas] => 213132-06-0
    [pslug] => 213132-06-0-sr-rr-nebivolol-pa1415530
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PA 14 15530
PA 14 15530

(SR,RR) Nebivolol


  • Catalogue No.:PA 14 15530

  • CAS :

    213132-06-0

  • Molecular Formula : C22H26ClF2NO4

  • Molecular Weight : 441.9

stdClass Object
(
    [pname] => L-Nebivolol Hydrochloride
    [catalogue_number] => PA 14 15540
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 441.9
    [form] => C22H26ClF2NO4
    [cas] => 920299-33-8
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PA 14 15540
PA 14 15540

L-Nebivolol Hydrochloride


  • Catalogue No.:PA 14 15540

  • CAS :

    920299-33-8

  • Molecular Formula : C22H26ClF2NO4

  • Molecular Weight : 441.9

stdClass Object
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    [pname] => A Mixture of (SRRS + RSSR)-Nebivolol
    [catalogue_number] => PA 14 15550
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 810.87
    [form] => C44H50F4N2O8
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PA 14 15550
PA 14 15550

A Mixture of (SRRS + RSSR)-Nebivolol


  • Catalogue No.:PA 14 15550

  • CAS :

    NA

  • Molecular Formula : C44H50F4N2O8

  • Molecular Weight : 810.87

stdClass Object
(
    [pname] => (RR,RR)-Nebivolol
    [catalogue_number] => PA 14 15560
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 405.44
    [form] => C22H25F2NO4
    [cas] => 119365-29-6
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PA 14 15560
PA 14 15560

(RR,RR)-Nebivolol


  • Catalogue No.:PA 14 15560

  • CAS :

    119365-29-6

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
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    [pname] => (R,R,S,S)-Nebivolol
    [catalogue_number] => PA 14 15570
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    [weight] => 405.44
    [form] => C22H25F2NO4
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PA 14 15570
PA 14 15570

(R,R,S,S)-Nebivolol


  • Catalogue No.:PA 14 15570

  • CAS :

    1360598-84-0

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
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    [pname] => (SS,SS)-Nebivolol
    [catalogue_number] => PA 14 15580
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    [weight] => 405.44
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PA 14 15580
PA 14 15580

(SS,SS)-Nebivolol


  • Catalogue No.:PA 14 15580

  • CAS :

    119365-28-5

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
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    [pname] => A Mixture of (SRRR + SSRS)-Nebivolol
    [catalogue_number] => PA 14 15590
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    [weight] => 810.87
    [form] => C44H50F4N2O8
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PA 14 15590
PA 14 15590

A Mixture of (SRRR + SSRS)-Nebivolol


  • Catalogue No.:PA 14 15590

  • CAS :

    NA

  • Molecular Formula : C44H50F4N2O8

  • Molecular Weight : 810.87

stdClass Object
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    [pname] => (RS,SR)-Nebivolol
    [catalogue_number] => PA 14 15600
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    [chemical_name] => 
    [weight] => 405.44
    [form] => C22H25F2NO4
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PA 14 15600
PA 14 15600

(RS,SR)-Nebivolol


  • Catalogue No.:PA 14 15600

  • CAS :

    119365-30-9

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
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    [pname] => (S,R,R,S)-Nebivolol
    [catalogue_number] => PA 14 15610
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    [chemical_name] => 
    [weight] => 405.44
    [form] => C22H25F2NO4
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PA 14 15610
PA 14 15610

(S,R,R,S)-Nebivolol


  • Catalogue No.:PA 14 15610

  • CAS :

    119365-23-0

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
(
    [pname] => (RSSR+SR,RS+SRRS)-Nebivolol
    [catalogue_number] => PA 14 15620
    [category_ids] => ,82,80,78,76,75,71,70,69,
    [chemical_name] => 
    [weight] => 441.90
    [form] => C22H26ClF2NO4
    [cas] => NA
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PA 14 15620
PA 14 15620

(RSSR+SR,RS+SRRS)-Nebivolol


  • Catalogue No.:PA 14 15620

  • CAS :

    NA

  • Molecular Formula : C22H26ClF2NO4

  • Molecular Weight : 441.90

stdClass Object
(
    [pname] => (RR,SS+RR,RR+SS,SS)-Nebivolol
    [catalogue_number] => PA 14 15630
    [category_ids] => ,82,80,78,76,75,71,70,69,
    [chemical_name] => 
    [weight] => 1325.69
    [form] => C66H78Cl3F6N3O12
    [cas] => NA
    [pslug] => rr-ssrr-rrss-ss-nebivolol-pa1415630
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PA 14 15630
PA 14 15630

(RR,SS+RR,RR+SS,SS)-Nebivolol


  • Catalogue No.:PA 14 15630

  • CAS :

    NA

  • Molecular Formula : C66H78Cl3F6N3O12

  • Molecular Weight : 1325.69

stdClass Object
(
    [pname] => D-Nebivolol
    [catalogue_number] => PA 14 15640
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    [weight] => 405.44
    [form] => C22H25F2NO4
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PA 14 15640
PA 14 15640

D-Nebivolol


  • Catalogue No.:PA 14 15640

  • CAS :

    118457-15-1

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
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    [pname] => (S)-1-((S)-6-Fluorochroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol
    [catalogue_number] => PA 14 15690
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PA 14 15690
PA 14 15690

(S)-1-((S)-6-Fluorochroman-2-yl)-2-(((R)-2-((S)-6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol


  • Catalogue No.:PA 14 15690

  • CAS :

    119365-25-2

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
(
    [pname] => 1-(Chroman-2-yl)-2-((2-(6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol Hydrochloride
    [catalogue_number] => PA 14 15700
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    [weight] => 423.91
    [form] => C22H27ClFNO4
    [cas] => NA
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PA 14 15700
PA 14 15700

1-(Chroman-2-yl)-2-((2-(6-fluorochroman-2-yl)-2-hydroxyethyl)amino)ethanol Hydrochloride


  • Catalogue No.:PA 14 15700

  • CAS :

    NA

  • Molecular Formula : C22H27ClFNO4

  • Molecular Weight : 423.91

stdClass Object
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    [pname] => rac N-Benzyl Nebivolol-d4
    [catalogue_number] => PA STI 011750
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    [weight] => 499.58
    [form] => C29H27D4F2NO4
    [cas] => 1246814-48-1
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PA STI 011750
PA STI 011750

rac N-Benzyl Nebivolol-d4


  • Catalogue No.:PA STI 011750

  • CAS :

    1246814-48-1

  • Molecular Formula : C29H27D4F2NO4

  • Molecular Weight : 499.58

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    [catalogue_number] => PA STI 041820
    [category_ids] => ,71,78,70,82,98,
    [chemical_name] => 
    [weight] => 196.21
    [form] => C11H9D2FO2
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PA STI 041820
PA STI 041820

6-Fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran-d2 (Mixture of Diastereomers)


  • Catalogue No.:PA STI 041820

  • CAS :

    1246820-42-7

  • Molecular Formula : C11H9D2FO2

  • Molecular Weight : 196.21

stdClass Object
(
    [pname] => (-)-Nebivolol-d4 Hydrochloride
    [catalogue_number] => PA STI 067120
    [category_ids] => ,69,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 445.92
    [form] => C22H22D4ClF2NO4
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PA STI 067120
PA STI 067120

(-)-Nebivolol-d4 Hydrochloride


  • Catalogue No.:PA STI 067120

  • CAS :

    NA

  • Molecular Formula : C22H22D4ClF2NO4

  • Molecular Weight : 445.92

stdClass Object
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    [pname] => (+)-Nebivolol-d4 Hydrochloride
    [catalogue_number] => PA STI 067130
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    [weight] => 445.92
    [form] => C22H22D4ClF2NO4
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PA STI 067130
PA STI 067130

(+)-Nebivolol-d4 Hydrochloride


  • Catalogue No.:PA STI 067130

  • CAS :

    NA

  • Molecular Formula : C22H22D4ClF2NO4

  • Molecular Weight : 445.92

stdClass Object
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    [pname] => rac Nebivolol-d8
    [catalogue_number] => PA STI 067140
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    [weight] => 413.48
    [form] => C22H17D8F2NO4
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PA STI 067140
PA STI 067140

rac Nebivolol-d8


  • Catalogue No.:PA STI 067140

  • CAS :

    1219166-00-3

  • Molecular Formula : C22H17D8F2NO4

  • Molecular Weight : 413.48

stdClass Object
(
    [pname] => rac Nebivolol-d4 (Major)
    [catalogue_number] => PA STI 067150
    [category_ids] => ,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 409.46
    [form] => C22H21D4F2NO4
    [cas] => 1219407-55-2
    [pslug] => 1219407-55-2-rac-nebivolol-d4-major-pasti067150
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PA STI 067150
PA STI 067150

rac Nebivolol-d4 (Major)


  • Catalogue No.:PA STI 067150

  • CAS :

    1219407-55-2

  • Molecular Formula : C22H21D4F2NO4

  • Molecular Weight : 409.46

stdClass Object
(
    [pname] => rac Nebivolol-d8 Hydrochloride
    [catalogue_number] => PA STI 067160
    [category_ids] => ,79,80,71,98,78,70,82,
    [chemical_name] => 
    [weight] => 449.95
    [form] => C22H18D8ClF2NO4
    [cas] => NA
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PA STI 067160
PA STI 067160

rac Nebivolol-d8 Hydrochloride


  • Catalogue No.:PA STI 067160

  • CAS :

    NA

  • Molecular Formula : C22H18D8ClF2NO4

  • Molecular Weight : 449.95

stdClass Object
(
    [pname] => (2S, 2'R)-6-Fluoro-2-(2'-oxiranyl)chromane
    [catalogue_number] => PA 14 15710
    [category_ids] => ,80,71,69,
    [chemical_name] => 
    [weight] => 194.21
    [form] => C11H11FO2
    [cas] => 197706-51-7
    [pslug] => 197706-51-7-2s-2r-6-fluoro-2-2-oxiranyl-chromane-pa1415710
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PA 14 15710
PA 14 15710

(2S, 2'R)-6-Fluoro-2-(2'-oxiranyl)chromane


  • Catalogue No.:PA 14 15710

  • CAS :

    197706-51-7

  • Molecular Formula : C11H11FO2

  • Molecular Weight : 194.21

stdClass Object
(
    [pname] => α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol (Mixture of Diastereomers)
    [catalogue_number] => PA 14 15730
    [category_ids] => ,79,80,71,78,70,82,
    [chemical_name] => 
    [weight] => 211.23
    [form] => C11H14FNO2
    [cas] => 897661-66-4
    [pslug] => 897661-66-4-alpha-aminomethyl-6-fluoro-3-4-dihydro-2h-1-benzopyran-2-methanol-mixture-of-diastereomers-pa1415730
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PA 14 15730
PA 14 15730

α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol (Mixture of Diastereomers)


  • Catalogue No.:PA 14 15730

  • CAS :

    897661-66-4

  • Molecular Formula : C11H14FNO2

  • Molecular Weight : 211.23

stdClass Object
(
    [pname] => (2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol
    [catalogue_number] => PA 14 15740
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 211.23
    [form] => C11H14FNO2
    [cas] => 303176-42-3
    [pslug] => 303176-42-3-2s-alpha-r-alpha-aminomethyl-6-fluoro-3-4-dihydro-2h-1-benzopyran-2-methanol-pa1415740
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PA 14 15740
PA 14 15740

(2S,αR)-α-(Aminomethyl)-6-fluoro-3,4-dihydro-2H-1-benzopyran-2-methanol


  • Catalogue No.:PA 14 15740

  • CAS :

    303176-42-3

  • Molecular Formula : C11H14FNO2

  • Molecular Weight : 211.23

stdClass Object
(
    [pname] => (R,S,R,S)-Nebivolol
    [catalogue_number] => PA 14 15720
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 405.44
    [form] => C22H25F2NO4
    [cas] => 119365-24-1
    [pslug] => 119365-24-1-r-s-r-s-nebivolol-pa1415720
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PA 14 15720
PA 14 15720

(R,S,R,S)-Nebivolol


  • Catalogue No.:PA 14 15720

  • CAS :

    119365-24-1

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
(
    [pname] => Nebivolol Isomer (SRSR+RSRS)
    [catalogue_number] => PA 14 0151033
    [category_ids] => ,69,70,71,78,82,
    [chemical_name] => 
    [weight] => 405.44
    [form] => C22H25F2NO4
    [cas] => NA
    [pslug] => nebivolol-isomer-srsr-rsrs-pa140151033
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PA 14 0151033
PA 14 0151033

Nebivolol Isomer (SRSR+RSRS)


  • Catalogue No.:PA 14 0151033

  • CAS :

    NA

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
(
    [pname] => (R)-2-((S)-6-Fluorochroman-2-yl)-2-(tosyloxy)ethyl Acetate compound with (S)-2-((R)-6-Fluorochroman-2-yl)-2-(tosyloxy)ethyl Acetate (1:1)
    [catalogue_number] => PA 14 0151035
    [category_ids] => ,82,78,71,69,
    [chemical_name] => 
    [weight] => 408.44
    [form] => C20H21FO6S
    [cas] => NA
    [pslug] => r-2-s-6-fluorochroman-2-yl-2-tosyloxy-ethyl-acetate-compound-with-s-2-r-6-fluorochroman-2-yl-2-tosyloxy-ethyl-acetate-1-1-pa140151035
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PA 14 0151035
PA 14 0151035

(R)-2-((S)-6-Fluorochroman-2-yl)-2-(tosyloxy)ethyl Acetate compound with (S)-2-((R)-6-Fluorochroman-2-yl)-2-(tosyloxy)ethyl Acetate (1:1)


  • Catalogue No.:PA 14 0151035

  • CAS :

    NA

  • Molecular Formula : C20H21FO6S

  • Molecular Weight : 408.44

stdClass Object
(
    [pname] => 2-Chloro-1-(6-fluorochroman-2-yl)ethan-1-ol
    [catalogue_number] => PA 14 0151037
    [category_ids] => ,69,70,71,78,82,
    [chemical_name] => 
    [weight] => 230.66
    [form] => C11H12ClFO2
    [cas] => 1017878-67-9
    [pslug] => 1017878-67-9-2-chloro-1-6-fluorochroman-2-yl-ethan-1-ol-pa140151037
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PA 14 0151037
PA 14 0151037

2-Chloro-1-(6-fluorochroman-2-yl)ethan-1-ol


  • Catalogue No.:PA 14 0151037

  • CAS :

    1017878-67-9

  • Molecular Formula : C11H12ClFO2

  • Molecular Weight : 230.66

stdClass Object
(
    [pname] => 2-(6-Fluorochroman-2-yl)-2-hydroxyacetic Acid
    [catalogue_number] => PA 14 0151041
    [category_ids] => ,69,70,71,78,82,
    [chemical_name] => 
    [weight] => 226.2
    [form] => C11H11FO4
    [cas] => NA
    [pslug] => 2-6-fluorochroman-2-yl-2-hydroxyacetic-acid-pa140151041
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PA 14 0151041
PA 14 0151041

2-(6-Fluorochroman-2-yl)-2-hydroxyacetic Acid


  • Catalogue No.:PA 14 0151041

  • CAS :

    NA

  • Molecular Formula : C11H11FO4

  • Molecular Weight : 226.2

stdClass Object
(
    [pname] => N-(2-(Chroman-2-yl)-2-hydroxyethyl)-N-(2-(6-fluorochroman-2-yl)-2-hydroxyethyl)nitrous amide
    [catalogue_number] => PA 14 0151042
    [category_ids] => ,69,70,71,78,82,
    [chemical_name] => 
    [weight] => 416.45
    [form] => C22H25FN2O5
    [cas] => NA
    [pslug] => n-2-chroman-2-yl-2-hydroxyethyl-n-2-6-fluorochroman-2-yl-2-hydroxyethyl-nitrous-amide-pa140151042
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PA 14 0151042
PA 14 0151042

N-(2-(Chroman-2-yl)-2-hydroxyethyl)-N-(2-(6-fluorochroman-2-yl)-2-hydroxyethyl)nitrous amide


  • Catalogue No.:PA 14 0151042

  • CAS :

    NA

  • Molecular Formula : C22H25FN2O5

  • Molecular Weight : 416.45

stdClass Object
(
    [pname] => Nebivolol Isomer (RSRR+RRRR)
    [catalogue_number] => PA 14 0151043
    [category_ids] => ,69,70,71,78,82,
    [chemical_name] => 
    [weight] => 405.44
    [form] => C22H25F2NO4
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PA 14 0151043
PA 14 0151043

Nebivolol Isomer (RSRR+RRRR)


  • Catalogue No.:PA 14 0151043

  • CAS :

    NA

  • Molecular Formula : C22H25F2NO4

  • Molecular Weight : 405.44

stdClass Object
(
    [pname] => (S)-2-((R)-6-Fluorochroman-2-yl)-2-(tosyloxy)ethyl acetate
    [catalogue_number] => PA 14 0151045
    [category_ids] => ,69,71,78,82,
    [chemical_name] => 
    [weight] => 408.44
    [form] => C20H21FO6S
    [cas] => 1345202-53-0
    [pslug] => 1345202-53-0-s-2-r-6-fluorochroman-2-yl-2-tosyloxy-ethyl-acetate-pa140151045
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PA 14 0151045
PA 14 0151045

(S)-2-((R)-6-Fluorochroman-2-yl)-2-(tosyloxy)ethyl acetate


  • Catalogue No.:PA 14 0151045

  • CAS :

    1345202-53-0

  • Molecular Formula : C20H21FO6S

  • Molecular Weight : 408.44

stdClass Object
(
    [pname] => Desfluoro Fam Nebivolol
    [catalogue_number] => PA 14 0151046
    [category_ids] => ,69,70,71,78,82,
    [chemical_name] => 
    [weight] => 387.45
    [form] => C22H26FNO4
    [cas] => NA
    [pslug] => desfluoro-fam-nebivolol-pa140151046
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PA 14 0151046
PA 14 0151046

Desfluoro Fam Nebivolol


  • Catalogue No.:PA 14 0151046

  • CAS :

    NA

  • Molecular Formula : C22H26FNO4

  • Molecular Weight : 387.45

stdClass Object
(
    [pname] => (S)-2-Chloro-1-((R)-6-fluorochroman-2-yl)ethan-1-ol
    [catalogue_number] => PA 14 0151047
    [category_ids] => ,69,70,71,78,82,
    [chemical_name] => 
    [weight] => 230.66
    [form] => C11H12ClFO2
    [cas] => 1315508-95-2
    [pslug] => 1315508-95-2-s-2-chloro-1-r-6-fluorochroman-2-yl-ethan-1-ol-pa140151047
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PA 14 0151047
PA 14 0151047

(S)-2-Chloro-1-((R)-6-fluorochroman-2-yl)ethan-1-ol


  • Catalogue No.:PA 14 0151047

  • CAS :

    1315508-95-2

  • Molecular Formula : C11H12ClFO2

  • Molecular Weight : 230.66

stdClass Object
(
    [pname] => (S)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl acetate
    [catalogue_number] => PA 14 0151049
    [category_ids] => ,69,70,71,78,82,
    [chemical_name] => 
    [weight] => 254.26
    [form] => C13H15FO4
    [cas] => 1345202-52-9
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PA 14 0151049
PA 14 0151049

(S)-2-((R)-6-fluorochroman-2-yl)-2-hydroxyethyl acetate


  • Catalogue No.:PA 14 0151049

  • CAS :

    1345202-52-9

  • Molecular Formula : C13H15FO4

  • Molecular Weight : 254.26

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