bortezomib

Bortezomib was approved for medical use in the United States in 2003 and in Europe in 2004. Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma.. Reference standards of Bortezomib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Bortezomib
    [catalogue_number] => PA 02 79000
    [category_ids] => 90,82,81,78,70,69
    [chemical_name] => 
    [weight] => 384.24
    [form] => C19H25BN4O4
    [cas] => 179324-69-7
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PA 02 79000

Bortezomib


  • Catalogue No.:PA 02 79000

  • CAS :

    179324-69-7

  • Molecular Formula : C19H25BN4O4

  • Molecular Weight : 384.24

stdClass Object
(
    [pname] => Bortezomib (1S,2R)-Isomer
    [catalogue_number] => PA 02 79530
    [category_ids] => 90,82,81,78,70,69
    [chemical_name] => 
    [weight] => 384.24
    [form] => C19H25BN4O4
    [cas] => 1132709-16-0
    [pslug] => 1132709-16-0-bortezomib-1s-2r-isomer-pa0279530
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PA 02 79530

Bortezomib (1S,2R)-Isomer


  • Catalogue No.:PA 02 79530

  • CAS :

    1132709-16-0

  • Molecular Formula : C19H25BN4O4

  • Molecular Weight : 384.24

stdClass Object
(
    [pname] => N-(1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
    [catalogue_number] => PA 02 79540
    [category_ids] => 90,81,69,78,82,70
    [chemical_name] => 
    [weight] => 356.42
    [form] => C19H24N4O3
    [cas] => 2747958-64-9
    [pslug] => 2747958-64-9-n-1-r-1-hydroxy-3-methylbutyl-amino-1-oxo-3-phenylpropan-2-yl-pyrazine-2-carboxamide-pa0279540
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PA 02 79540

N-(1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


  • Catalogue No.:PA 02 79540

  • CAS :

    2747958-64-9

  • Molecular Formula : C19H24N4O3

  • Molecular Weight : 356.42

stdClass Object
(
    [pname] => Bortezomib Amide analog (Mixture of isomers)
    [catalogue_number] => PA 02 79550
    [category_ids] => 90,81,69,70,78,82
    [chemical_name] => 
    [weight] => 270.29
    [form] => C14H14N4O2
    [cas] => 2748159-75-1
    [pslug] => 2748159-75-1-bortezomib-amide-analog-mixture-of-isomers-pa0279550
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PA 02 79550

Bortezomib Amide analog (Mixture of isomers)


  • Catalogue No.:PA 02 79550

  • CAS :

    2748159-75-1

  • Molecular Formula : C14H14N4O2

  • Molecular Weight : 270.29

stdClass Object
(
    [pname] => N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide
    [catalogue_number] => PA 02 79560
    [category_ids] => ,69,90,81,78,70,82,
    [chemical_name] => 
    [weight] => 340.42
    [form] => C19H24N4O2
    [cas] => 1446194-56-4
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PA 02 79560

N-[(1S)-2-[(3-Methylbutyl)amino]-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide


  • Catalogue No.:PA 02 79560

  • CAS :

    1446194-56-4

  • Molecular Formula : C19H24N4O2

  • Molecular Weight : 340.42

stdClass Object
(
    [pname] => (R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic Acid
    [catalogue_number] => PA 02 79570
    [category_ids] => 69,70,78,81,82,90
    [chemical_name] => 
    [weight] => 237.06
    [form] => C10H16BN3O3
    [cas] => NA
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PA 02 79570

(R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic Acid


  • Catalogue No.:PA 02 79570

  • CAS :

    NA

  • Molecular Formula : C10H16BN3O3

  • Molecular Weight : 237.06

stdClass Object
(
    [pname] => N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
    [catalogue_number] => PA 02 79580
    [category_ids] => 90,81,69,78,82,70
    [chemical_name] => 
    [weight] => 340.42
    [form] => C19H24N4O2
    [cas] => 2797440-80-1
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PA 02 79580

N-(1-(Isopentylamino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


  • Catalogue No.:PA 02 79580

  • CAS :

    2797440-80-1

  • Molecular Formula : C19H24N4O2

  • Molecular Weight : 340.42

stdClass Object
(
    [pname] => (4-Hydroxy-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic Acid
    [catalogue_number] => PA 02 79590
    [category_ids] => ,69,90,81,78,70,82,
    [chemical_name] => 
    [weight] => 386.21
    [form] => C18H23BN4O5
    [cas] => NA
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PA 02 79590

(4-Hydroxy-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic Acid


  • Catalogue No.:PA 02 79590

  • CAS :

    NA

  • Molecular Formula : C18H23BN4O5

  • Molecular Weight : 386.21

stdClass Object
(
    [pname] => N-(1-((1-(3a,5-Dimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
    [catalogue_number] => PA 02 79600
    [category_ids] => ,69,90,81,78,70,82,
    [chemical_name] => 
    [weight] => 504.43
    [form] => C28H37BN4O4
    [cas] => NA
    [pslug] => n-1-1-3a-5-dimethylhexahydro-4-6-methanobenzo-d-1-3-2-dioxaborol-2-yl-3-methylbutyl-amino-1-oxo-3-phenylpropan-2-yl-pyrazine-2-carboxamide-pa0279600
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PA 02 79600

N-(1-((1-(3a,5-Dimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


  • Catalogue No.:PA 02 79600

  • CAS :

    NA

  • Molecular Formula : C28H37BN4O4

  • Molecular Weight : 504.43

stdClass Object
(
    [pname] => (R)-2-(N-Methylpyrazine-2-carboxamido)-3-phenylpropanoic Acid
    [catalogue_number] => PA 02 79610
    [category_ids] => ,69,90,81,78,70,82,
    [chemical_name] => 
    [weight] => 285.3
    [form] => C15H15N3O3
    [cas] => NA
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PA 02 79610

(R)-2-(N-Methylpyrazine-2-carboxamido)-3-phenylpropanoic Acid


  • Catalogue No.:PA 02 79610

  • CAS :

    NA

  • Molecular Formula : C15H15N3O3

  • Molecular Weight : 285.3

stdClass Object
(
    [pname] => 3-Hydroxy Bortezomib
    [catalogue_number] => PA 02 79630
    [category_ids] => 82,81,78,70
    [chemical_name] => 
    [weight] => 400.24
    [form] => C19H25BN4O5
    [cas] => NA
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PA 02 79630

3-Hydroxy Bortezomib


  • Catalogue No.:PA 02 79630

  • CAS :

    NA

  • Molecular Formula : C19H25BN4O5

  • Molecular Weight : 400.24

stdClass Object
(
    [pname] => Bortezomib-D8 (Major)
    [catalogue_number] => PA STI 014210
    [category_ids] => ,69,90,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 392.29
    [form] => C19H17D8BN4O4
    [cas] => NA
    [pslug] => bortezomib-d8-major-pasti014210
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PA STI 014210

Bortezomib-D8 (Major)


  • Catalogue No.:PA STI 014210

  • CAS :

    NA

  • Molecular Formula : C19H17D8BN4O4

  • Molecular Weight : 392.29

stdClass Object
(
    [pname] => (1R,2R)-Bortezomib-d5
    [catalogue_number] => PA STI 014220
    [category_ids] => ,69,90,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 389.27
    [form] => C19H20D5BN4O4
    [cas] => NA
    [pslug] => 1r-2r-bortezomib-d5-pasti014220
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PA STI 014220

(1R,2R)-Bortezomib-d5


  • Catalogue No.:PA STI 014220

  • CAS :

    NA

  • Molecular Formula : C19H20D5BN4O4

  • Molecular Weight : 389.27

stdClass Object
(
    [pname] => (1S,2R)-Bortezomib-d5
    [catalogue_number] => PA STI 014230
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    [chemical_name] => 
    [weight] => 389.27
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PA STI 014230

(1S,2R)-Bortezomib-d5


  • Catalogue No.:PA STI 014230

  • CAS :

    NA

  • Molecular Formula : C19H20D5BN4O4

  • Molecular Weight : 389.27

stdClass Object
(
    [pname] => (1S,2S)-Bortezomib-d5
    [catalogue_number] => PA STI 014240
    [category_ids] => ,69,90,81,78,70,82,98,
    [chemical_name] => 
    [weight] => 389.27
    [form] => C19H20D5BN4O4
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PA STI 014240

(1S,2S)-Bortezomib-d5


  • Catalogue No.:PA STI 014240

  • CAS :

    NA

  • Molecular Formula : C19H20D5BN4O4

  • Molecular Weight : 389.27

stdClass Object
(
    [pname] => N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
    [catalogue_number] => PA 02 0791038
    [category_ids] => ,90,82,81,78,70,69,
    [chemical_name] => 
    [weight] => 356.43
    [form] => C19H24N4O3
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PA 02 0791038

N-((R)-1-(((R)-1-Hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


  • Catalogue No.:PA 02 0791038

  • CAS :

    NA

  • Molecular Formula : C19H24N4O3

  • Molecular Weight : 356.43

stdClass Object
(
    [pname] => Bortezomib Amide analog (R-Isomer)
    [catalogue_number] => PA 02 0791040
    [category_ids] => 90,82,81,78,70,69
    [chemical_name] => 
    [weight] => 270.29
    [form] => C14H14N4O2
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PA 02 0791040

Bortezomib Amide analog (R-Isomer)


  • Catalogue No.:PA 02 0791040

  • CAS :

    2185388-96-7

  • Molecular Formula : C14H14N4O2

  • Molecular Weight : 270.29

stdClass Object
(
    [pname] => rel-(R)-3-Methyl-1-((3aS,4R,6R,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate
    [catalogue_number] => PA 02 0791043
    [category_ids] => ,82,81,78,70,69,
    [chemical_name] => 
    [weight] => 379.23
    [form] => C17H29BF3NO4
    [cas] => 1310383-72-2
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PA 02 0791043

rel-(R)-3-Methyl-1-((3aS,4R,6R,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine 2,2,2-trifluoroacetate


  • Catalogue No.:PA 02 0791043

  • CAS :

    1310383-72-2

  • Molecular Formula : C17H29BF3NO4

  • Molecular Weight : 379.23

stdClass Object
(
    [pname] => Bortezomib Mannitol
    [catalogue_number] => PA 02 0791044
    [category_ids] => ,82,81,78,70,69,
    [chemical_name] => 
    [weight] => 530.39
    [form] => C25H35BN4O8
    [cas] => 444576-08-3
    [pslug] => 444576-08-3-bortezomib-mannitol-pa020791044
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PA 02 0791044

Bortezomib Mannitol


  • Catalogue No.:PA 02 0791044

  • CAS :

    444576-08-3

  • Molecular Formula : C25H35BN4O8

  • Molecular Weight : 530.39

stdClass Object
(
    [pname] => N-((R)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide
    [catalogue_number] => PA 02 0791046
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    [chemical_name] => 
    [weight] => 356.43
    [form] => C19H24N4O3
    [cas] => NA
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PA 02 0791046

N-((R)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide


  • Catalogue No.:PA 02 0791046

  • CAS :

    NA

  • Molecular Formula : C19H24N4O3

  • Molecular Weight : 356.43

CPHI INDIA- 28, 30 November