Tezacaftor
Tezacaftor is used to treat cystic fibrosis in certain people. It is a drug that is sold as a fixed-dose combination with ivacaftor as Symdeko.Reference standards of Tezacaftor API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object
(
[pname] => Tezacaftor
[catalogue_number] => PA 47 98000
[category_ids] => ,80,79,78,70,82,89,
[chemical_name] =>
[weight] => 520.51
[form] => C26H27F3N2O6
[cas] => 1152311-62-0
[pslug] => 1152311-62-0-tezacaftor-api-pa4798000
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Catalogue No.:PA 47 98000
Molecular Formula : C26H27F3N2O6
Molecular Weight : 520.51
stdClass Object
(
[pname] => Tezacaftor Enantiomer
[catalogue_number] => PA 47 0981004
[category_ids] => ,80,79,78,70,82,89,
[chemical_name] =>
[weight] => 520.51
[form] => C26H27F3N2O6
[cas] => 1152311-99-3
[pslug] => 1152311-99-3-tezacaftor-enantiomer-pa470981004
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Catalogue No.:PA 47 0981004
Molecular Formula : C26H27F3N2O6
Molecular Weight : 520.51
stdClass Object
(
[pname] => Acetonide O-Benzyl Tezacaftor
[catalogue_number] => PA 47 0981007
[category_ids] => ,80,79,78,70,82,
[chemical_name] =>
[weight] => 650.7
[form] => C36H37F3N2O6
[cas] => NA
[pslug] => acetonide-o-benzyl-tezacaftor-pa470981007
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Acetonide O-Benzyl Tezacaftor
stdClass Object
(
[pname] => (S)-1-(5-amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol
[catalogue_number] => PA 47 0981011
[category_ids] => ,80,79,78,70,82,89,
[chemical_name] =>
[weight] => 476.59
[form] => C29H33FN2O3
[cas] => NA
[pslug] => s-1-5-amino-2-1-benzyloxy-2-methylpropan-2-yl-6-fluoro-1h-indol-1-yl-3-benzyloxy-propan-2-ol-pa470981011
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(S)-1-(5-amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol
Catalogue No.:PA 47 0981011
Molecular Formula : C29H33FN2O3
Molecular Weight : 476.59
stdClass Object
(
[pname] => (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-4-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
[catalogue_number] => PA 47 0981012
[category_ids] => ,80,79,78,70,82,
[chemical_name] =>
[weight] => 520.51
[form] => C26H27F3N2O6
[cas] => NA
[pslug] => r-1-2-2-difluorobenzo-d-1-3-dioxol-5-yl-n-1-2-3-dihydroxypropyl-4-fluoro-2-1-hydroxy-2-methylpropan-2-yl-1h-indol-5-yl-cyclopropane-1-carboxamide-pa470981012
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(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-4-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
Catalogue No.:PA 47 0981012
Molecular Formula : C26H27F3N2O6
Molecular Weight : 520.51
stdClass Object
(
[pname] => 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(6-(2,3-dihydroxypropoxy)-1-(2,3-dihydroxypropyl)-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
[catalogue_number] => PA 47 0981013
[category_ids] => ,80,79,78,70,82,
[chemical_name] =>
[weight] => 592.59
[form] => C29H34F2N2O9
[cas] => NA
[pslug] => 1-2-2-difluorobenzo-d-1-3-dioxol-5-yl-n-6-2-3-dihydroxypropoxy-1-2-3-dihydroxypropyl-2-1-hydroxy-2-methylpropan-2-yl-1h-indol-5-yl-cyclopropane-1-carboxamide-pa470981013
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1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(6-(2,3-dihydroxypropoxy)-1-(2,3-dihydroxypropyl)-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
Catalogue No.:PA 47 0981013
Molecular Formula : C29H34F2N2O9
Molecular Weight : 592.59
stdClass Object
(
[pname] => 3-(5-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-1-yl)-2-hydroxypropyl acetate
[catalogue_number] => PA 47 0981014
[category_ids] => ,80,79,78,70,82,
[chemical_name] =>
[weight] => 562.54
[form] => C28H29F3N2O7
[cas] => NA
[pslug] => 3-5-1-2-2-difluorobenzo-d-1-3-dioxol-5-yl-cyclopropane-1-carboxamido-6-fluoro-2-1-hydroxy-2-methylpropan-2-yl-1h-indol-1-yl-2-hydroxypropyl-acetate-pa470981014
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3-(5-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-1-yl)-2-hydroxypropyl acetate
Catalogue No.:PA 47 0981014
Molecular Formula : C28H29F3N2O7
Molecular Weight : 562.54
