Tezacaftor

Tezacaftor is used to treat cystic fibrosis in certain people. It is a drug that is sold as a fixed-dose combination with ivacaftor as Symdeko.Reference standards of Tezacaftor API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Tezacaftor
    [catalogue_number] => PA 47 98000
    [category_ids] => ,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 520.51
    [form] => C26H27F3N2O6
    [cas] => 1152311-62-0
    [pslug] => 1152311-62-0-tezacaftor-api-pa4798000
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PA 47 98000

Tezacaftor


  • Catalogue No.:PA 47 98000

  • CAS :

    1152311-62-0

  • Molecular Formula : C26H27F3N2O6

  • Molecular Weight : 520.51

stdClass Object
(
    [pname] => Tezacaftor Enantiomer
    [catalogue_number] => PA 47 0981004
    [category_ids] => ,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 520.51
    [form] => C26H27F3N2O6
    [cas] => 1152311-99-3
    [pslug] => 1152311-99-3-tezacaftor-enantiomer-pa470981004
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PA 47 0981004

Tezacaftor Enantiomer


  • Catalogue No.:PA 47 0981004

  • CAS :

    1152311-99-3

  • Molecular Formula : C26H27F3N2O6

  • Molecular Weight : 520.51

stdClass Object
(
    [pname] => Acetonide O-Benzyl Tezacaftor
    [catalogue_number] => PA 47 0981007
    [category_ids] => ,80,79,78,70,82,
    [chemical_name] => 
    [weight] => 650.7
    [form] => C36H37F3N2O6
    [cas] => NA
    [pslug] => acetonide-o-benzyl-tezacaftor-pa470981007
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PA 47 0981007

Acetonide O-Benzyl Tezacaftor


  • Catalogue No.:PA 47 0981007

  • CAS :

    NA

  • Molecular Formula : C36H37F3N2O6

  • Molecular Weight : 650.7

stdClass Object
(
    [pname] => (S)-1-(5-amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol
    [catalogue_number] => PA 47 0981011
    [category_ids] => ,80,79,78,70,82,89,
    [chemical_name] => 
    [weight] => 476.59
    [form] => C29H33FN2O3
    [cas] => NA
    [pslug] => s-1-5-amino-2-1-benzyloxy-2-methylpropan-2-yl-6-fluoro-1h-indol-1-yl-3-benzyloxy-propan-2-ol-pa470981011
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PA 47 0981011

(S)-1-(5-amino-2-(1-(benzyloxy)-2-methylpropan-2-yl)-6-fluoro-1H-indol-1-yl)-3-(benzyloxy)propan-2-ol


  • Catalogue No.:PA 47 0981011

  • CAS :

    NA

  • Molecular Formula : C29H33FN2O3

  • Molecular Weight : 476.59

stdClass Object
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    [pname] => (R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-4-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
    [catalogue_number] => PA 47 0981012
    [category_ids] => ,80,79,78,70,82,
    [chemical_name] => 
    [weight] => 520.51
    [form] => C26H27F3N2O6
    [cas] => NA
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PA 47 0981012

(R)-1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-4-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide


  • Catalogue No.:PA 47 0981012

  • CAS :

    NA

  • Molecular Formula : C26H27F3N2O6

  • Molecular Weight : 520.51

stdClass Object
(
    [pname] => 1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(6-(2,3-dihydroxypropoxy)-1-(2,3-dihydroxypropyl)-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide
    [catalogue_number] => PA 47 0981013
    [category_ids] => ,80,79,78,70,82,
    [chemical_name] => 
    [weight] => 592.59
    [form] => C29H34F2N2O9
    [cas] => NA
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PA 47 0981013

1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)-N-(6-(2,3-dihydroxypropoxy)-1-(2,3-dihydroxypropyl)-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropane-1-carboxamide


  • Catalogue No.:PA 47 0981013

  • CAS :

    NA

  • Molecular Formula : C29H34F2N2O9

  • Molecular Weight : 592.59

stdClass Object
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    [pname] => 3-(5-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-1-yl)-2-hydroxypropyl acetate
    [catalogue_number] => PA 47 0981014
    [category_ids] => ,80,79,78,70,82,
    [chemical_name] => 
    [weight] => 562.54
    [form] => C28H29F3N2O7
    [cas] => NA
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PA 47 0981014

3-(5-(1-(2,2-Difluorobenzo[d][1,3]dioxol-5-yl)cyclopropane-1-carboxamido)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-1-yl)-2-hydroxypropyl acetate


  • Catalogue No.:PA 47 0981014

  • CAS :

    NA

  • Molecular Formula : C28H29F3N2O7

  • Molecular Weight : 562.54