Irinotecan Hydrochloride and its Impurities

Irinotecan Hydrochloride main use is in colon cancer, in particular, in combination with other chemotherapy agents. This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil, leucovorin, and irinotecan. It is sold under the brand name Camptosar. Reference standards of Irinotecan Hydrochloride API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.