Eribulin Mesylate and its Impurities

Eribulin Mesylate, sold under the brand name Halaven, is an anticancer medication used to treat breast cancer and liposarcoma. Reference standards of Eribulin Mesylate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

Displaying 7 results for Eribulin Mesylate Impurities

Eribulin Mesylate

Catalogue No.:PA 05 1810000
CAS :
441045-17-6
Molecular Formula : C₄₁H₆₃NO₁₄S
Molecular Weight : 826.01

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(1R,3S,8S,11S,14S,16R,18R,20S,22R,23R,24S,28R,31S,33S,34R,35S,37S)-22-[(2S)-3-Amino-2-hydroxypropyl]-34,37-dihydroxy-23-methoxy-16-methyl-10,17-dimethylidene2,21,32,36,38,39-hexaoxaheptacyclo[26.6.2.13,33.18,11.114,18.020,24.031,35 ]nonatriacontane-5,26-dione

(1R,3S,8S,11S,14S,16R,18R,20S,22R,23R,24S,28R,31S,33S,34R,35S,37S)-22-[(2S)-3-Amino-2-hydroxypropyl]-34,37-dihydroxy-23-methoxy-16-methyl-10,17-dimethylidene2,21,32,36,38,39-hexaoxaheptacyclo[26.6.2.13,33.18,11.114,18.020,24.031,35 ]nonatriacontane-5,26-dione

Catalogue No.:PA 05 1811000
CAS :
NA
Molecular Formula : C₄₀H₆₁NO₁₂
Molecular Weight : 747.92

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7,11:10,14:13,16:21,24:27,31-Pentaepoxy-2H-cyclohentriaconta[b]furan-5,18(3H,4H)-dione, 2-[(2S)-3-amino-2-hydroxypropyl]octacosahydro-12,15-dihydroxy-3-methoxy-29-methyl-23,30-bis(methylene)-, (2R,3R,3aS,7R,10S,11R,12S,13S,14S,15S,16R,21S,24S,27S,29R,31R,32aS)

7,11:10,14:13,16:21,24:27,31-Pentaepoxy-2H-cyclohentriaconta[b]furan-5,18(3H,4H)-dione, 2-[(2S)-3-amino-2-hydroxypropyl]octacosahydro-12,15-dihydroxy-3-methoxy-29-methyl-23,30-bis(methylene)-, (2R,3R,3aS,7R,10S,11R,12S,13S,14S,15S,16R,21S,24S,27S,29R,31R,32aS)

Catalogue No.:PA 05 1811001
CAS :
1534341-96-2
Molecular Formula : C₄₀H₆₁NO₁₂
Molecular Weight : 747.92

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(1R,2S,3S,4S,5S,6R,11S,14S,17S,19R,21R,23S,25R,26R,27S,31R,34S)-25-[(2S)-3-Amino-2-hydroxypropyl]-2,5-dihydroxy-26-methoxy-19-methyl-13,20-dimethylidene-24,35,36,37,38,39-hexaoxaheptacyclo[29.3.1.13,6.14,34.111,14.117,21.023,27]nonatriacontane-8,29-dione

(1R,2S,3S,4S,5S,6R,11S,14S,17S,19R,21R,23S,25R,26R,27S,31R,34S)-25-[(2S)-3-Amino-2-hydroxypropyl]-2,5-dihydroxy-26-methoxy-19-methyl-13,20-dimethylidene-24,35,36,37,38,39-hexaoxaheptacyclo[29.3.1.13,6.14,34.111,14.117,21.023,27]nonatriacontane-8,29-dione

Catalogue No.:PA 05 1811002
CAS :
NA
Molecular Formula : C₄₀H₆₁NO₁₂
Molecular Weight : 747.92

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Eribulin Impurity 1

Catalogue No.:PA 05 1811003
CAS :
NA
Molecular Formula : C₄₀H₆₁NO₁₂
Molecular Weight : 747.92

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(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2R)-3-Amino-2-hydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2R)-3-Amino-2-hydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

Catalogue No.:PA 05 1811004
CAS :
1190091-21-4
Molecular Formula : C₄₀H₅₉NO₁₁
Molecular Weight : 729.91

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(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2S)-2,3-Dihydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2?,3?:5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2S)-2,3-Dihydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2?,3?:5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

Catalogue No.:PA 05 1811005
CAS :
253128-15-3
Molecular Formula : C₄₀H₅₈O₁₂
Molecular Weight : 730.89

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Eribulin Mesylate and its Impurities

Eribulin Mesylate

441045-17-6

(1R,3S,8S,11S,14S,16R,18R,20S,22R,23R,24S,28R,31S,33S,34R,35S,37S)-22-[(2S)-3-Amino-2-hydroxypropyl]-34,37-dihydroxy-23-methoxy-16-methyl-10,17-dimethylidene2,21,32,36,38,39-hexaoxaheptacyclo[26.6.2.13,33.18,11.114,18.020,24.031,35 ]nonatriacontane-5,26-dione

NA

7,11:10,14:13,16:21,24:27,31-Pentaepoxy-2H-cyclohentriaconta[b]furan-5,18(3H,4H)-dione, 2-[(2S)-3-amino-2-hydroxypropyl]octacosahydro-12,15-dihydroxy-3-methoxy-29-methyl-23,30-bis(methylene)-, (2R,3R,3aS,7R,10S,11R,12S,13S,14S,15S,16R,21S,24S,27S,29R,31R,32aS)

1534341-96-2

(1R,2S,3S,4S,5S,6R,11S,14S,17S,19R,21R,23S,25R,26R,27S,31R,34S)-25-[(2S)-3-Amino-2-hydroxypropyl]-2,5-dihydroxy-26-methoxy-19-methyl-13,20-dimethylidene-24,35,36,37,38,39-hexaoxaheptacyclo[29.3.1.13,6.14,34.111,14.117,21.023,27]nonatriacontane-8,29-dione

NA

Eribulin Impurity 1

NA

(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2R)-3-Amino-2-hydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

1190091-21-4

(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2S)-2,3-Dihydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2?,3?:5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

253128-15-3

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Eribulin Mesylate and its Impurities

Eribulin Mesylate

441045-17-6

(1R,3S,8S,11S,14S,16R,18R,20S,22R,23R,24S,28R,31S,33S,34R,35S,37S)-22-[(2S)-3-Amino-2-hydroxypropyl]-34,37-dihydroxy-23-methoxy-16-methyl-10,17-dimethylidene2,21,32,36,38,39-hexaoxaheptacyclo[26.6.2.13,33.18,11.114,18.020,24.031,35 ]nonatriacontane-5,26-dione

NA

7,11:10,14:13,16:21,24:27,31-Pentaepoxy-2H-cyclohentriaconta[b]furan-5,18(3H,4H)-dione, 2-[(2S)-3-amino-2-hydroxypropyl]octacosahydro-12,15-dihydroxy-3-methoxy-29-methyl-23,30-bis(methylene)-, (2R,3R,3aS,7R,10S,11R,12S,13S,14S,15S,16R,21S,24S,27S,29R,31R,32aS)

1534341-96-2

(1R,2S,3S,4S,5S,6R,11S,14S,17S,19R,21R,23S,25R,26R,27S,31R,34S)-25-[(2S)-3-Amino-2-hydroxypropyl]-2,5-dihydroxy-26-methoxy-19-methyl-13,20-dimethylidene-24,35,36,37,38,39-hexaoxaheptacyclo[29.3.1.13,6.14,34.111,14.117,21.023,27]nonatriacontane-8,29-dione

NA

Eribulin Impurity 1

NA

(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2R)-3-Amino-2-hydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

1190091-21-4

(2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-2-[(2S)-2,3-Dihydroxypropyl]-3-methoxy-26-methyl-20,27-dimethylidenehexacosahydro-11,15:18,21:24,28-triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2?,3?:5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one

253128-15-3

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