astemizole and its Impurities
Astemizole is rapidly absorbed from the gastrointestinal tract and competitively binds to histamine H1 receptor sites in the gastrointestinal tract, uterus, blood vessels, and bronchial muscle. It is a histamine H1-receptor antagonist. It has anticholinergic and antipruritic effects.. Reference standards of Astemizole API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
