Name: 4-((6-Amino-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile
Brand: Pharmaffliates
Rating: 3.50 (5 reviews)

Catalogue number:	PA 05 0951001
Chemical name:	4-((6-Amino-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile
CAS Number:	939431-68-2
Category:	impurities,metabolites,intermediates,pharmaceutical standards,Fine Chemicals
Synonyms:	Etravirine Impurity D (As per 35.1 EP Monograph); 4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile; Benzonitrile, 4-[[6-amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethyl-;
Molecular form:	C₂₀H₁₆N₆O
Appearance:	NA
Mol. Weight:	356.39
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	4-[[6-Amino-2-[(4-cyanophenyl)amino]-4-pyrimidinyl]oxy]-3,5-dimethylbenzonitrile is an impurity of Etravirine, which is a novel HIV reverse transcriptase inhibitor useful in treatment of HIV infection. It can be used as a novel HIV-1 NNRTIs by using its hydrophobic channel and tolerant regions of NNIBP. It can also be used to synthesize etravirine, a non-nucleoside reverse transcriptase inhibitor.

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4-((6-Amino-2-((4-cyanophenyl)amino)pyrimidin-4-yl)oxy)-3,5-dimethylbenzonitrile

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