Name: PF-06380101
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA PEP 002530
Chemical name:	PF-06380101
CAS Number:	1436391-86-4
Category:	peptides,Antibody Drug Conjugate
Synonyms:	L-Valinamide, 2-methylalanyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; 2-Methylalanyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[[(1S)-2-phenyl-1-(2-thiazolyl)ethyl]amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-L-valinamide; Auristatin 0101; PF 101;
Molecular form:	C₃₉H₆₂N₆O₆S
Appearance:	Solid
Mol. Weight:	743.02
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	PF-06380101 (Aur0101), an auristatin microtubule inhibitor, is a cytotoxic Dolastatin 10 analogue. PF-06380101 (Aur0101) shows excellent potencies in tumor cell proliferation assays and differential ADME properties when compared to other synthetic auristatin analogues that are used in the preparation of ADCs

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PF-06380101

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