DBCO-C6-acid

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Catalogue number:	PA 27 0031436
Chemical name:	DBCO-C6-acid
CAS Number:	1425485-72-8
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	Dibenz[b,f]azocine-5(6H)-hexanoic acid, 11,12-didehydro-ε-oxo-; 11,12-Didehydro-ε-oxodibenz[b,f]azocine-5(6H)-hexanoic acid;
Molecular form:	C₂₁H₁₉NO₃
Appearance:	Solid
Mol. Weight:	333.39
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	DBCO-C6-acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). DBCO-C6-acid can be used in the synthesis of carmaphycin analogues[1]. DBCO- C6- acid is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups