Catalogue number: | PA 11 0031001 |
Chemical name: | (2R,4R)-trans-Ketoconazole |
CAS Number: |
142128-58-3 |
Category: | enzyme activators,enzyme inhibitors,impurities,metabolites,intermediates,pharmaceutical standards,Fine Chemicals |
Synonyms: | 1-Acetyl-4-[4-[[(2R,4R)-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; (2R-trans)-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine; 1-(4-(4-(((2R,4R)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethan-1-one; |
Molecular form: | C26H28Cl2N4O4 |
Appearance: | NA |
Mol. Weight: | 531.43 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | (2R,4R)-trans-Ketoconazole is an isomer of Ketoconazole (K186000). Ketoconazole inhibits cytochrome P-450 dependent steps in the biosynthesis of steroid hormones in vivo. It has antimetastatic and antineoplastic activity and is an orally active 5-lipoxygenase and thromboxane synthase inhibitor. |
(2R,4R)-trans-Ketoconazole
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