Name: NODA-GA-NHS ester
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 27 0031478
Chemical name:	NODA-GA-NHS ester
CAS Number:	1407166-70-4
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	2,2'-(7-(1-carboxy-4-((2,5-dioxopyrrolidin-1-yl)oxy)-4-oxobutyl)-1,4,7-triazonane-1,4-diyl)diacetic acid; 1H-1,4,7-Triazonine-1,4,7-triacetic acid, α1-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]hexahydro-; Nodaga-nhs; NODAGA NHS ester;
Molecular form:	C₁₉H₂₈N₄O₁₀
Appearance:	NA
Mol. Weight:	472.45
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	NODAGA-NHS (NODA-GA-NHS ester) is a [64]Cu chelator and the dissociated form of DOTA-trastuzumab in vivo. NODAGA-NHS was added in 0.1 M borate buffer at a ratio of 5/20/100 and was able to effectively bind trastuzumab (10 mg/mL) (4°C, 20 h). The copper content of the [64]Cu-NODAGA-trastuzumab was up to 80%. After blood was drawn from the caudal vein of mice, [64]Cu-NODAGA-trastuzumab was injected and showed good tumor uptake in mice expressing HER2 tumors, showing good PET imaging tracking ability

Enquire for NODA-GA-NHS ester

NODA-GA-NHS ester

CAS Number: