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Catalogue number: PA PEP 002523
Chemical name: NHS-MMAF

CAS Number:

1404073-19-3

Category: peptides,Antibody Drug Conjugate
Synonyms:

((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-((6-((2,5-dioxopyrrolidin-1-yl)oxy)-6-oxohexyl)(methyl)amino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine; L-Phenylalanine, N-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-; N-[6-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-N-methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine;

Molecular form: C49H78N6O12
Appearance: Solid
Mol. Weight: 943.19
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: NHS-MMAF is a modified MMAF extracted from patent WO2012143499, intermediat 219. MMAF is a potent tubulin polymerization inhibitor and is used as a antitumor agent

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