Name: DBCO-NHS ester 3
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA 27 0031409
Chemical name:	DBCO-NHS ester 3
CAS Number:	1393350-27-0
Category:	miscellaneous compounds,Antibody Drug Conjugate
Synonyms:	Dibenz[b,f]azocine-5(6H)-pentanoic acid, 11,12-didehydro-δ-oxo-, 2,5-dioxo-1-pyrrolidinyl ester; 2,5-Dioxo-1-pyrrolidinyl 11,12-didehydro-δ-oxodibenz[b,f]azocine-5(6H)-pentanoate; DIBAC-NHS Ester;
Molecular form:	C₂₄H₂₀N₂O₅
Appearance:	Solid
Mol. Weight:	416.43
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	DBCO-NHS ester 3 (Compound 12) is a cleavable linker that is used for making antibody-drug conjugate (ADC). DBCO-NHS ester 3 is a derivative of Dibenzylcyclooctyne (DBCO) obtained by activation of N-hydroxysuccinimide by the carboxylic acid moiety of both methyl-oxanorbornadiene (MeOND) and dibenzoazacyclooctyne (DIBAC)[1][2]. DBCO-NHS ester 3 is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups

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DBCO-NHS ester 3

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