Seco-DUBA

In House Impurity

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Catalogue number:	PA 04 3141000
Chemical name:	Seco-DUBA
CAS Number:	1227961-59-2
Category:	pharmaceutical standards,intermediates,Fine Chemicals,Antibody Drug Conjugate
Synonyms:	(S)-N-(2-(1-(chloromethyl)-5-hydroxy-9-methyl-2,3-dihydro-1H-naphtho[2,1-b]pyrrole-3-carbonyl)imidazo[1,2-a]pyridin-6-yl)-4-hydroxybenzamide; Benzamide, N-[2-[[(1S)-1-(chloromethyl)-1,2-dihydro-5-hydroxy-9-methyl-3H-benz[e]indol-3-yl]carbonyl]imidazo[1,2-a]pyridin-6-yl]-4-hydroxy-; N-[2-[[(1S)-1-(Chloromethyl)-1,2-dihydro-5-hydroxy-9-methyl-3H-benz[e]indol-3-yl]carbonyl]imidazo[1,2-a]pyridin-6-yl]-4-hydroxybenzamide; Seco-duocarmycin;
Molecular form:	C₂₉H₂₃ClN₄O₄
Appearance:	Solid
Mol. Weight:	526.98
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Seco-DUBA is a duocarmycin (DUBA) prodrug containing two hydroxyl groups, which can each be used for coupling to an antibody via a linker. Seco-DUBA can be used in the synthesis of antibody-drug conjugates (ADCs)