trans-Ned-19-d8

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Catalogue number:	PA STI 067180
Chemical name:	trans-Ned-19-d8
CAS Number:	NA
Category:	aromatics,heterocycles,indole derivatives,enzyme inhibitors,stable isotopes,fluorescent labels and indicators,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-(piperazinyl-d8)]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;
Molecular form:	C₃₀H₂₃D₈FN₄O₃
Appearance:	NA
Mol. Weight:	522.64
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Labelled trans-Ned-19, a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells.