Catalogue number: | PA STI 067180 |
Chemical name: | trans-Ned-19-d8 |
CAS Number: |
NA |
Category: | aromatics,heterocycles,indole derivatives,enzyme inhibitors,stable isotopes,fluorescent labels and indicators,pharmaceutical standards,intermediates,Fine Chemicals |
Synonyms: | (1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-(piperazinyl-d8)]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid; |
Molecular form: | C30H23D8FN4O3 |
Appearance: | NA |
Mol. Weight: | 522.64 |
Storage: | 2-8°C Refrigerator |
Shipping Conditions: | Ambient |
Applications: | Labelled trans-Ned-19, a cell permeable and potent nicotinic acid adenine dinucleotide phosphate (NAADP) antagonist. trans-Ned-19 inhibits NAADP-mediated Ca2+ release (IC50 = 6 nM) and also inhibits [32P]NAADP binding (IC50 = 0.4 nM). trans-Ned-19 can be used as a chemical proble since it fluorescentey labels NAADP receptors in intact cells. |
trans-Ned-19-d8
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