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Catalogue number: PA STI 080800
Chemical name: TAK-960-d3

CAS Number:

NA

Category: miscellaneous compounds,stable isotopes
Synonyms:

4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-2-fluoro-5-methoxy-N-(1-methyl-4-piperidinyl)benzamide-d3;

Molecular form: CH31D3F3N7O3
Appearance: NA
Mol. Weight: 564.62
Storage: 2-8°C Refrigerator
Shipping Conditions: Ambient
Applications: Isotope labelled TAK-960 is a potent and selective inhibitor of polo-like kinase 1 (PLK1), a serine/threonine protein kinase involved in key processes during mitosis. TAK-960 has shown activity in several tumor cell lines, including those that express multidrug-resistant protein 1 (MDR1). TAK-960 treatments has shown significant efficacy against multiple tumor xenografts and is a potential chemotherapeutic agent for patients with advanced tumors.

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