Name: Romidepsin-d8
Brand: Pharmaffliates
Rating: 4.00 (5 reviews)

Catalogue number:	PA STI 077990
Chemical name:	Romidepsin-d8
CAS Number:	NA
Category:	heterocycles,enzyme inhibitors,stable isotopes,pharmaceutical standards,intermediates,Fine Chemicals
Synonyms:	Cyclo[(2Z)-2-amino-2-butenoyl-L-valyl-(3S,4E)-3-hydroxy-7-mercapto-4-heptenoyl-D-valyl-D-cysteinyl]-d8 Cyclic (35)-Disulfide; [S-(E)]-N-(3-Hydroxy-7-mercapto-1-oxo-4-heptenyl)-D-valyl-D-cysteinyl-(Z)-2,3-didehydro-2-aminobutanoyl-L-valine (4-1)-Lactone-d8 Cyclic (12)-Disulfide; Antibiotic FR 901228-d8; Chromadax-d8; FK 228-d8; FR 901228-d8; NSC 630176-d8;
Molecular form:	C₂₄H₂₈D₈N₄O₆S₂
Appearance:	NA
Mol. Weight:	548.75
Storage:	2-8°C Refrigerator
Shipping Conditions:	Ambient
Applications:	Labelled Romidepsin. Romidepsin is a histone deacetylase inhibitor that can alter chromatin structure and gene transcription leading to multiple changes in cellular protein production. This may result in cell cycle arrest and tumor growth inhibition. Romidepsin has shown anti-proliferative activity in vitro against multiple mouse and human tumor cell lines and in vivo in human tumor xenograft models. Romidepsin can be administered with a second agent, such as a cytotoxic agent, a steroidal agent, a proteasome inhibitor, or a kinase inhibitor.

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Romidepsin-d8

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