Vonoprazan

Vonoprazan is used in form of the fumarate for the treatment of gastroduodenal ulcer and reflux esophagitis. It is a first-in-class potassium-competitive acid blocker.Reference standards of Vonoprazan API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Vonoprazan
    [catalogue_number] => PA 22 47000
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 345.39
    [form] => C17H16FN3O2S
    [cas] => 881681-00-1
    [pslug] => 881681-00-1-vonoprazan-api-pa2247000
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PA 22 47000

Vonoprazan

  • Catalogue No.:PA 22 47000

  • CAS :

    881681-00-1

  • Molecular Formula : C17H16FN3O2S

  • Molecular Weight : 345.39

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stdClass Object
(
    [pname] =>  (5-(2-Fluorophenyl)-1H-pyrrol-3-yl)methanol
    [catalogue_number] => PA 22 0471030
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 191.21
    [form] => C11H10FNO
    [cas] => 881674-58-4
    [pslug] => 881674-58-4-5-2-fluorophenyl-1h-pyrrol-3-yl-methanol-pa220471030
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PA 22 0471030

 (5-(2-Fluorophenyl)-1H-pyrrol-3-yl)methanol

  • Catalogue No.:PA 22 0471030

  • CAS :

    881674-58-4

  • Molecular Formula : C11H10FNO

  • Molecular Weight : 191.21

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stdClass Object
(
    [pname] => 5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbonitrile
    [catalogue_number] => PA 22 0471031
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 327.33
    [form] => C16H10FN3O2S
    [cas] => 1807642-39-2
    [pslug] => 1807642-39-2-5-2-fluorophenyl-1-pyridin-3-ylsulfonyl-1h-pyrrole-3-carbonitrile-pa220471031
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PA 22 0471031

5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carbonitrile

  • Catalogue No.:PA 22 0471031

  • CAS :

    1807642-39-2

  • Molecular Formula : C16H10FN3O2S

  • Molecular Weight : 327.33

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stdClass Object
(
    [pname] => Vonoprazan N-Methyl Asparmic Acid Impurity
    [catalogue_number] => PA 22 0471032
    [category_ids] => ,79,80,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 461.46
    [form] => C21H20FN3O6S
    [cas] => 2170020-79-6
    [pslug] => 2170020-79-6-vonoprazan-n-methyl-asparmic-acid-impurity-pa220471032
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PA 22 0471032

Vonoprazan N-Methyl Asparmic Acid Impurity

  • Catalogue No.:PA 22 0471032

  • CAS :

    2170020-79-6

  • Molecular Formula : C21H20FN3O6S

  • Molecular Weight : 461.46

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stdClass Object
(
    [pname] => N-((5-(2-Fluorophenyl)-1-((6-hydroxy-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide
    [catalogue_number] => PA 22 0471035
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 394.42
    [form] => C17H19FN4O4S
    [cas] => NA
    [pslug] => n-5-2-fluorophenyl-1-6-hydroxy-1-4-5-6-tetrahydropyridin-3-yl-sulfonyl-1h-pyrrol-3-yl-methyl-n-methylnitrous-amide-pa220471035
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PA 22 0471035

N-((5-(2-Fluorophenyl)-1-((6-hydroxy-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide

  • Catalogue No.:PA 22 0471035

  • CAS :

    NA

  • Molecular Formula : C17H19FN4O4S

  • Molecular Weight : 394.42

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stdClass Object
(
    [pname] => 5-((2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)-1-nitroso-1,2,3,4-tetrahydropyridin-2-ol
    [catalogue_number] => PA 22 0471036
    [category_ids] => ,70,78,79,80,82,88,89,162,
    [chemical_name] => 
    [weight] => 394.42
    [form] => C17H19FN4O4S
    [cas] => NA
    [pslug] => 5-2-2-fluorophenyl-4-methylamino-methyl-1h-pyrrol-1-yl-sulfonyl-1-nitroso-1-2-3-4-tetrahydropyridin-2-ol-pa220471036
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PA 22 0471036

5-((2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)-1-nitroso-1,2,3,4-tetrahydropyridin-2-ol

  • Catalogue No.:PA 22 0471036

  • CAS :

    NA

  • Molecular Formula : C17H19FN4O4S

  • Molecular Weight : 394.42

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Details 
stdClass Object
(
    [pname] => N-((5-(2-Fluorophenyl)-1-((6-hydroxy-1-nitroso-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide
    [catalogue_number] => PA 22 0471037
    [category_ids] => ,70,78,79,80,82,88,89,162,
    [chemical_name] => 
    [weight] => 423.42
    [form] => C17H18FN5O5S
    [cas] => NA
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PA 22 0471037

N-((5-(2-Fluorophenyl)-1-((6-hydroxy-1-nitroso-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide

  • Catalogue No.:PA 22 0471037

  • CAS :

    NA

  • Molecular Formula : C17H18FN5O5S

  • Molecular Weight : 423.42

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stdClass Object
(
    [pname] => N-((5-(2-Fluorophenyl)-1-((1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide
    [catalogue_number] => PA 22 0471038
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 378.42
    [form] => C17H19FN4O3S
    [cas] => NA
    [pslug] => n-5-2-fluorophenyl-1-1-4-5-6-tetrahydropyridin-3-yl-sulfonyl-1h-pyrrol-3-yl-methyl-n-methylnitrous-amide-pa220471038
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PA 22 0471038

N-((5-(2-Fluorophenyl)-1-((1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide

  • Catalogue No.:PA 22 0471038

  • CAS :

    NA

  • Molecular Formula : C17H19FN4O3S

  • Molecular Weight : 378.42

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Details 
stdClass Object
(
    [pname] => 1-(5-(2-Fluorophenyl)-1-((1-nitroso-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine
    [catalogue_number] => PA 22 0471039
    [category_ids] => ,70,78,79,80,82,88,89,162,
    [chemical_name] => 
    [weight] => 378.42
    [form] => C17H19FN4O3S
    [cas] => NA
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PA 22 0471039

1-(5-(2-Fluorophenyl)-1-((1-nitroso-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)-N-methylmethanamine

  • Catalogue No.:PA 22 0471039

  • CAS :

    NA

  • Molecular Formula : C17H19FN4O3S

  • Molecular Weight : 378.42

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stdClass Object
(
    [pname] => N-((5-(2-Fluorophenyl)-1-((1-nitroso-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide
    [catalogue_number] => PA 22 0471040
    [category_ids] => ,70,78,79,80,82,88,89,162,
    [chemical_name] => 
    [weight] => 407.42
    [form] => C17H18FN5O4S
    [cas] => NA
    [pslug] => n-5-2-fluorophenyl-1-1-nitroso-1-4-5-6-tetrahydropyridin-3-yl-sulfonyl-1h-pyrrol-3-yl-methyl-n-methylnitrous-amide-pa220471040
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PA 22 0471040

N-((5-(2-Fluorophenyl)-1-((1-nitroso-1,4,5,6-tetrahydropyridin-3-yl)sulfonyl)-1H-pyrrol-3-yl)methyl)-N-methylnitrous Amide

  • Catalogue No.:PA 22 0471040

  • CAS :

    NA

  • Molecular Formula : C17H18FN5O4S

  • Molecular Weight : 407.42

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stdClass Object
(
    [pname] => ((5-(2-Fluoro-4-hydroxyphenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)(methyl)sulfamic Acid
    [catalogue_number] => PA 22 0471048
    [category_ids] => ,78,70,82,88,
    [chemical_name] => 
    [weight] => 441.45
    [form] => C17H16FN3O6S2
    [cas] => 1883595-40-1
    [pslug] => 1883595-40-1-5-2-fluoro-4-hydroxyphenyl-1-pyridin-3-ylsulfonyl-1h-pyrrol-3-yl-methyl-methyl-sulfamic-acid-pa220471048
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PA 22 0471048

((5-(2-Fluoro-4-hydroxyphenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)(methyl)sulfamic Acid

  • Catalogue No.:PA 22 0471048

  • CAS :

    1883595-40-1

  • Molecular Formula : C17H16FN3O6S2

  • Molecular Weight : 441.45

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stdClass Object
(
    [pname] => N-Nitroso Vonoprazan-D4
    [catalogue_number] => PA STI 089728
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 378.41
    [form] => C17H11D4FN4O3S
    [cas] => NA
    [pslug] => n-nitroso-vonoprazan-d4-pasti089728
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PA STI 089728

N-Nitroso Vonoprazan-D4

  • Catalogue No.:PA STI 089728

  • CAS :

    NA

  • Molecular Formula : C17H11D4FN4O3S

  • Molecular Weight : 378.41

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stdClass Object
(
    [pname] => Ethyl 2-cyano-4-(2-fluorophenyl)-4-oxobutanoate
    [catalogue_number] => PA 22 0471056
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 249.24
    [form] => C13H12FNO3
    [cas] => 881673-98-9
    [pslug] => 881673-98-9-ethyl-2-cyano-4-2-fluorophenyl-4-oxobutanoate-pa220471056
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PA 22 0471056

Ethyl 2-cyano-4-(2-fluorophenyl)-4-oxobutanoate

  • Catalogue No.:PA 22 0471056

  • CAS :

    881673-98-9

  • Molecular Formula : C13H12FNO3

  • Molecular Weight : 249.24

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stdClass Object
(
    [pname] => Ethyl 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate
    [catalogue_number] => PA 22 0471057
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 267.68
    [form] => C13H11ClFNO2
    [cas] => 881674-01-7
    [pslug] => 881674-01-7-ethyl-2-chloro-5-2-fluorophenyl-1h-pyrrole-3-carboxylate-pa220471057
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PA 22 0471057

Ethyl 2-chloro-5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate

  • Catalogue No.:PA 22 0471057

  • CAS :

    881674-01-7

  • Molecular Formula : C13H11ClFNO2

  • Molecular Weight : 267.68

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Details 
stdClass Object
(
    [pname] => Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate
    [catalogue_number] => PA 22 0471058
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 233.24
    [form] => C13H12FNO2
    [cas] => 881674-06-2
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PA 22 0471058

Ethyl 5-(2-fluorophenyl)-1H-pyrrole-3-carboxylate

  • Catalogue No.:PA 22 0471058

  • CAS :

    881674-06-2

  • Molecular Formula : C13H12FNO2

  • Molecular Weight : 233.24

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Details 
stdClass Object
(
    [pname] => 5-(2-Fluorophenyl)-N-methyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxamide
    [catalogue_number] => PA 22 0471060
    [category_ids] => ,79,80,78,70,82,88,89,
    [chemical_name] => 
    [weight] => 359.38
    [form] => C17H14FN3O3S
    [cas] => 2054536-04-6
    [pslug] => 2054536-04-6-5-2-fluorophenyl-n-methyl-1-pyridin-3-ylsulfonyl-1h-pyrrole-3-carboxamide-pa220471060
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PA 22 0471060

5-(2-Fluorophenyl)-N-methyl-1-(pyridin-3-ylsulfonyl)-1H-pyrrole-3-carboxamide

  • Catalogue No.:PA 22 0471060

  • CAS :

    2054536-04-6

  • Molecular Formula : C17H14FN3O3S

  • Molecular Weight : 359.38

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stdClass Object
(
    [pname] => N-((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)ethanamine
    [catalogue_number] => PA 22 0471061
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 359.42
    [form] => C18H18FN3O2S
    [cas] => 2247546-53-6
    [pslug] => 2247546-53-6-n-5-2-fluorophenyl-1-pyridin-3-ylsulfonyl-1h-pyrrol-3-yl-methyl-ethanamine-pa220471061
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PA 22 0471061

N-((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)ethanamine

  • Catalogue No.:PA 22 0471061

  • CAS :

    2247546-53-6

  • Molecular Formula : C18H18FN3O2S

  • Molecular Weight : 359.42

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stdClass Object
(
    [pname] => N-((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)ethanamine Hydrochloride
    [catalogue_number] => PA 22 0471062
    [category_ids] => ,79,80,78,70,82,88,
    [chemical_name] => 
    [weight] => 395.88
    [form] => C18H19ClFN3O2S
    [cas] => NA
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)
PA 22 0471062

N-((5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl)methyl)ethanamine Hydrochloride

  • Catalogue No.:PA 22 0471062

  • CAS :

    NA

  • Molecular Formula : C18H19ClFN3O2S

  • Molecular Weight : 395.88

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CPHI INDIA- 28, 30 November