A second-generation protease inhibitor, it is used for the treatment of HIV infections. It is administered along with ritonavir or cobicistat, to decrease metabolism and increase concentration.. Reference standards of Darunavir API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
stdClass Object ( [pname] => [(1S,2R)-1-Benzyl-2-hydroxy-3-[isobutyl-[(4-aminophenyl)sulfonyl]amino] propyl]carbamic Acid tert-Butyl Ester [catalogue_number] => PA 04 06510 [category_ids] => ,69,70,88, [chemical_name] => [weight] => 491.64 [form] => C25H37N3O5S [cas] => 183004-94-6 [pslug] => 183004-94-6-1s-2r-1-benzyl-2-hydroxy-3-isobutyl-4-aminophenyl-sulfonyl-amino-propyl-carbamic-acid-tert-butyl-ester-pa0406510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06510
CAS :
Molecular Formula : C25H37N3O5S
Molecular Weight : 491.64
stdClass Object ( [pname] => Darunavir Urea Impurity [catalogue_number] => PA 04 06580 [category_ids] => ,80,79,78,82,70,88, [chemical_name] => [weight] => 417.52 [form] => C21H27N3O4S [cas] => 2514705-71-4 [pslug] => 2514705-71-4-darunavir-urea-impurity-pa0406580 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06580
Molecular Formula : C21H27N3O4S
Molecular Weight : 417.52
stdClass Object ( [pname] => Darunavir Amine Dimer Impurity [catalogue_number] => PA 04 06590 [category_ids] => ,80,79,78,82,70,88,71, [chemical_name] => [weight] => 965.19 [form] => C48H64N6O11S2 [cas] => NA [pslug] => darunavir-amine-dimer-impurity-pa0406590 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06590
Molecular Formula : C48H64N6O11S2
Molecular Weight : 965.19
stdClass Object ( [pname] => Darunavir Furan Dimer Impurity [catalogue_number] => PA 04 06600 [category_ids] => ,80,79,78,82,70,88,71, [chemical_name] => [weight] => 703.8 [form] => C34H45N3O11S [cas] => NA [pslug] => darunavir-furan-dimer-impurity-pa0406600 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06600
Molecular Formula : C34H45N3O11S
Molecular Weight : 703.8
stdClass Object ( [pname] => Benzyl (2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydrxy-1-phenylbutan-2-yl)ureido)-N-isobutylsulfonamido)-3-hydroxy-1-phenylbutan-2-ylcarbamate [catalogue_number] => PA 04 06610 [category_ids] => ,80,79,78,82,70,88,71, [chemical_name] => [weight] => 867.09 [form] => C43H58N6O9S2 [cas] => NA [pslug] => benzyl-2s-3r-4-4-3-2s-3r-4-4-amino-n-isobutylphenylsulfonamido-3-hydrxy-1-phenylbutan-2-yl-ureido-n-isobutylsulfonamido-3-hydroxy-1-phenylbutan-2-ylcarbamate-pa0406610 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06610
Molecular Formula : C43H58N6O9S2
Molecular Weight : 867.09
stdClass Object ( [pname] => [(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenylmethyl)propyl]-Carbamic Acid Phenylmethyl Ester [catalogue_number] => PA 04 06620 [category_ids] => ,80,79,78,82,70,88, [chemical_name] => [weight] => 525.66 [form] => C28H35N3O5S [cas] => 159005-61-5 [pslug] => 159005-61-5-1s-2r-3-4-aminophenyl-sulfonyl-2-methylpropyl-amino-2-hydroxy-1-phenylmethyl-propyl-carbamic-acid-phenylmethyl-ester-pa0406620 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06620
Molecular Formula : C28H35N3O5S
Molecular Weight : 525.66
stdClass Object ( [pname] => ((2S,3R)-4-(4-(((((3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl)oxy)carbonyl)amino)-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamic Acid Phenylmethyl Ester [catalogue_number] => PA 04 06630 [category_ids] => ,80,79,78,82,70,88, [chemical_name] => [weight] => 681.8 [form] => C35H43N3O9S [cas] => NA [pslug] => 2s-3r-4-4-3r-3as-6ar-hexahydrofuro-2-3-b-furan-3-yl-oxy-carbonyl-amino-n-isobutylphenylsulfonamido-3-hydroxy-1-phenylbutan-2-yl-carbamic-acid-phenylmethyl-ester-pa0406630 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06630
Molecular Formula : C35H43N3O9S
Molecular Weight : 681.8
stdClass Object ( [pname] => (+)-Darunavir [catalogue_number] => PA 04 06640 [category_ids] => ,80,79,78,82,70,88, [chemical_name] => [weight] => 547.66 [form] => C27H37N3O7S [cas] => 1399859-60-9 [pslug] => 1399859-60-9-darunavir-pa0406640 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06640
Molecular Formula : C27H37N3O7S
Molecular Weight : 547.66
stdClass Object ( [pname] => Darunavir Carbamic Acid Impurity [catalogue_number] => PA 04 06660 [category_ids] => ,80,71,78,70,82,79,88, [chemical_name] => [weight] => 435.54 [form] => C21H29N3O5S [cas] => 1526916-56-2 [pslug] => 1526916-56-2-darunavir-carbamic-acid-impurity-pa0406660 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06660
Molecular Formula : C21H29N3O5S
Molecular Weight : 435.54
stdClass Object ( [pname] => [(1S,2R)-3-[[(4-Aminophenyl)sulfonyl](2-methylpropyl)amino]-2-hydroxy-1-(phenyl-methyl)propyl]carabamic Acid Methyl Ester [catalogue_number] => PA 04 06680 [category_ids] => ,75,88,70,82, [chemical_name] => [weight] => 449.56 [form] => C22H31N3O5S [cas] => 1526916-57-3 [pslug] => 1526916-57-3-1s-2r-3-4-aminophenyl-sulfonyl-2-methylpropyl-amino-2-hydroxy-1-phenyl-methyl-propyl-carabamic-acid-methyl-ester-pa0406680 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06680
Molecular Formula : C22H31N3O5S
Molecular Weight : 449.56
stdClass Object ( [pname] => (3R,3aS,6aR)-Hexahydrofuro[2,3-b]furan-3-yl ((2S,3R)-4-(4-(3-((2S,3R)-4-(4-amino-N-isobutylphenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)-1-isobutylureido)phenylsulfonamido)-3-hydroxy-1-phenylbutan-2-yl)carbamate [catalogue_number] => PA 04 06690 [category_ids] => ,75,88,70,82, [chemical_name] => [weight] => 965.19 [form] => C48H64N6O11S2 [cas] => NA [pslug] => 3r-3as-6ar-hexahydrofuro-2-3-b-furan-3-yl-2s-3r-4-4-3-2s-3r-4-4-amino-n-isobutylphenylsulfonamido-3-hydroxy-1-phenylbutan-2-yl-1-isobutylureido-phenylsulfonamido-3-hydroxy-1-phenylbutan-2-yl-carbamate-pa0406690 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06690
stdClass Object ( [pname] => 4-Amino-N-((2S,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide [catalogue_number] => PA 04 06730 [category_ids] => ,79,80,78,70,82,88,75, [chemical_name] => [weight] => 391.53 [form] => C20H29N3O3S [cas] => 192800-79-6 [pslug] => 192800-79-6-4-amino-n-2s-3s-3-amino-2-hydroxy-4-phenylbutyl-n-isobutylbenzenesulfonamide-pa0406730 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06730
Molecular Formula : C20H29N3O3S
Molecular Weight : 391.53
stdClass Object ( [pname] => 4-Amino-N-((2S,3R)-3-amino-2-hydroxy-4-phenylbutyl)-N-isobutylbenzenesulfonamide [catalogue_number] => PA 04 06740 [category_ids] => ,79,80,78,70,82,88,75, [chemical_name] => [weight] => 391.53 [form] => C20H29N3O3S [cas] => 1402142-62-4 [pslug] => 1402142-62-4-4-amino-n-2s-3r-3-amino-2-hydroxy-4-phenylbutyl-n-isobutylbenzenesulfonamide-pa0406740 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06740
stdClass Object ( [pname] => 4-Amino-N-((2R,3S)-3-amino-2-hydroxy-4-phenylbutyl)-N-(isobutyl-d9)benzenesulfonamide [catalogue_number] => PA STI 005160 [category_ids] => ,79,80,76,75,78,70,82,88,98, [chemical_name] => [weight] => 400.58 [form] => C20H20D9N3O3S [cas] => 1146967-60-3 [pslug] => 1146967-60-3-4-amino-n-2r-3s-3-amino-2-hydroxy-4-phenylbutyl-n-isobutyl-d9-benzenesulfonamide-pasti005160 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 005160
Molecular Formula : C20H20D9N3O3S
Molecular Weight : 400.58
stdClass Object ( [pname] => 2,5-Dioxopyrrolidin-1-yl ((3R,3aR,6aS)-hexahydrofuro[2,3-b]furan-3-yl) Carbonate [catalogue_number] => PA 04 06820 [category_ids] => ,69,70,88, [chemical_name] => [weight] => 271.23 [form] => C11H13NO7 [cas] => 799241-86-4 [pslug] => 799241-86-4-2-5-dioxopyrrolidin-1-yl-3r-3ar-6as-hexahydrofuro-2-3-b-furan-3-yl-carbonate-pa0406820 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 06820
Molecular Formula : C11H13NO7
Molecular Weight : 271.23
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