Chlorobutanol Hemihydrate is formed by the reaction of chloroform and acetone in the presence of potassium or sodium hydroxide. It is a preservative, sedative, hypnotic and weak local anesthetic similar in nature to chloral hydrate.. Reference standards of Chlorobutanol Hemihydrate API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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