Zanubrutinib, sold under the brand name Brukinsa, is for the treatment of adult patients with mantle cell lymphoma (MCL) who have received at least one prior therapy. Reference standards of Zanubrutinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => (S)-7-(1-Acryloylpiperidin-4-yl)-4-nitroso-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide [catalogue_number] => PA 26 0391000 [category_ids] => ,70,75,76,78,82,162, [chemical_name] => [weight] => 500.56 [form] => C27H28N6O4 [cas] => NA [pslug] => s-7-1-acryloylpiperidin-4-yl-4-nitroso-2-4-phenoxyphenyl-4-5-6-7-tetrahydropyrazolo-1-5-a-pyrimidine-3-carboxamide-pa260391000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391000
CAS :
Molecular Formula : C27H28N6O4
Molecular Weight : 500.56
stdClass Object ( [pname] => Zanubrutinib - API Standards [catalogue_number] => PA 26 0390000 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 471.56 [form] => C27H29N5O3 [cas] => 1691249-45-2 [pslug] => 1691249-45-2-zanubrutinib-api-pa260390000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0390000
Molecular Formula : C27H29N5O3
Molecular Weight : 471.56
stdClass Object ( [pname] => Zanubrutinib R-Isomer [catalogue_number] => PA 26 0391001 [category_ids] => ,75,78,82, [chemical_name] => [weight] => 471.56 [form] => C27H29N5O3 [cas] => 1691249-44-1 [pslug] => 1691249-44-1-zanubrutinib-r-isomer-pa260391001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391001
stdClass Object ( [pname] => (S)-7-(1-(3-Chloropropanoyl)piperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide [catalogue_number] => PA 26 0391002 [category_ids] => ,75,78,70,82, [chemical_name] => [weight] => 508.02 [form] => C27H30ClN5O3 [cas] => 1633351-79-7 [pslug] => 1633351-79-7-s-7-1-3-chloropropanoyl-piperidin-4-yl-2-4-phenoxyphenyl-4-5-6-7-tetrahydropyrazolo-1-5-a-pyrimidine-3-carboxamide-pa260391002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391002
Molecular Formula : C27H30ClN5O3
Molecular Weight : 508.02
stdClass Object ( [pname] => (S)-7-(1-Acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carbonitrile [catalogue_number] => PA 26 0391003 [category_ids] => ,75,78,70,82, [chemical_name] => [weight] => 453.55 [form] => C27H27N5O2 [cas] => 2432022-47-2 [pslug] => 2432022-47-2-s-7-1-acryloylpiperidin-4-yl-2-4-phenoxyphenyl-4-5-6-7-tetrahydropyrazolo-1-5-a-pyrimidine-3-carbonitrile-pa260391003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391003
Molecular Formula : C27H27N5O2
Molecular Weight : 453.55
stdClass Object ( [pname] => 5-Amino-3-(4-phenoxyphenyl)-1H-pyrazole-4-carbonitrile [catalogue_number] => PA 26 0391004 [category_ids] => ,75,76,78,82, [chemical_name] => [weight] => 276.3 [form] => C16H12N4O [cas] => NA [pslug] => 5-amino-3-4-phenoxyphenyl-1h-pyrazole-4-carbonitrile-pa260391004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391004
Molecular Formula : C16H12N4O
Molecular Weight : 276.3
stdClass Object ( [pname] => 3-(4-(3-Carbamoyl-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidin-7-yl)piperidin-1-yl)propanoic Acid [catalogue_number] => PA 26 0391005 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 489.58 [form] => C27H31N5O4 [cas] => NA [pslug] => 3-4-3-carbamoyl-2-4-phenoxyphenyl-4-5-6-7-tetrahydropyrazolo-1-5-a-pyrimidin-7-yl-piperidin-1-yl-propanoic-acid-pa260391005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391005
Molecular Formula : C27H31N5O4
Molecular Weight : 489.58
stdClass Object ( [pname] => 2-(4-Phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine [catalogue_number] => PA 26 0391006 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 374.49 [form] => C23H26N4O [cas] => NA [pslug] => 2-4-phenoxyphenyl-7-piperidin-4-yl-4-5-6-7-tetrahydropyrazolo-1-5-a-pyrimidine-pa260391006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391006
Molecular Formula : C23H26N4O
Molecular Weight : 374.49
stdClass Object ( [pname] => 4-Acryloyl-7-(1-acryloylpiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide [catalogue_number] => PA 26 0391007 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 525.61 [form] => C30H31N5O4 [cas] => NA [pslug] => 4-acryloyl-7-1-acryloylpiperidin-4-yl-2-4-phenoxyphenyl-4-5-6-7-tetrahydropyrazolo-1-5-a-pyrimidine-3-carboxamide-pa260391007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391007
Molecular Formula : C30H31N5O4
Molecular Weight : 525.61
stdClass Object ( [pname] => (S)-4-Nitroso-2-(4-phenoxyphenyl)-7-(piperidin-4-yl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide [catalogue_number] => PA 26 0391008 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 446.51 [form] => C24H26N6O3 [cas] => NA [pslug] => s-4-nitroso-2-4-phenoxyphenyl-7-piperidin-4-yl-4-5-6-7-tetrahydropyrazolo-1-5-a-pyrimidine-3-carboxamide-pa260391008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391008
Molecular Formula : C24H26N6O3
Molecular Weight : 446.51
stdClass Object ( [pname] => (S)-7-(1-Nitrosopiperidin-4-yl)-2-(4-phenoxyphenyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidine-3-carboxamide [catalogue_number] => PA 26 0391009 [category_ids] => ,70,75,76,78,82, [chemical_name] => [weight] => 446.51 [form] => C24H26N6O3 [cas] => NA [pslug] => s-7-1-nitrosopiperidin-4-yl-2-4-phenoxyphenyl-4-5-6-7-tetrahydropyrazolo-1-5-a-pyrimidine-3-carboxamide-pa260391009 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 26 0391009
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