Sacubitril-impurities | Pharmaffiliates

sacubitril

An antihypertensive drug, Sacubitril is used in combination with valsartan for the treatment of heart ailments. A prodrug of sacubitrilat which is an inhibitor of enzyme neprilysin, which aids the degradation of blood pressure-lowering peptides, atrial and brain natriuretic peptide.Reference standards of Sacubitril API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-isopropoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate
    [catalogue_number] => PA 19 0661076
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 889.11
    [form] => C50H60CaN2O10
    [cas] => 2984580-05-2
    [pslug] => 2984580-05-2-calcium-4-2s-4r-1-1-1-biphenyl-4-yl-5-isopropoxy-4-methyl-5-oxopentan-2-yl-amino-4-oxobutanoate-pa190661076
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PA 19 0661076

Calcium 4-(((2S,4R)-1-([1,1'-biphenyl]-4-yl)-5-isopropoxy-4-methyl-5-oxopentan-2-yl)amino)-4-oxobutanoate


  • Catalogue No.:PA 19 0661076

  • CAS :

    2984580-05-2

  • Molecular Formula : C50H60CaN2O10

  • Molecular Weight : 889.11

stdClass Object
(
    [pname] => rel-4-((3R,5S)-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl)-4-oxobutanoic Acid
    [catalogue_number] => PA 19 0661077
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 365.43
    [form] => C22H23NO4
    [cas] => 2216746-87-9
    [pslug] => 2216746-87-9-rel-4-3r-5s-5-1-1-biphenyl-4-ylmethyl-3-methyl-2-oxopyrrolidin-1-yl-4-oxobutanoic-acid-pa190661077
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PA 19 0661077

rel-4-((3R,5S)-5-([1,1'-Biphenyl]-4-ylmethyl)-3-methyl-2-oxopyrrolidin-1-yl)-4-oxobutanoic Acid


  • Catalogue No.:PA 19 0661077

  • CAS :

    2216746-87-9

  • Molecular Formula : C22H23NO4

  • Molecular Weight : 365.43

stdClass Object
(
    [pname] => Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate
    [catalogue_number] => PA 19 0661078
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 439.55
    [form] => C26H33NO5
    [cas] => 2376611-98-0
    [pslug] => 2376611-98-0-ethyl-2r-4s-5-1-1-biphenyl-4-yl-4-4-ethoxy-4-oxobutanamido-2-methylpentanoate-pa190661078
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PA 19 0661078

Ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-(4-ethoxy-4-oxobutanamido)-2-methylpentanoate


  • Catalogue No.:PA 19 0661078

  • CAS :

    2376611-98-0

  • Molecular Formula : C26H33NO5

  • Molecular Weight : 439.55