Roflumilast-impurities | Pharmaffiliates

roflumilast

Roflumilast is used in the prevention of lung attacks in severe COPD. It is a long-acting inhibitor of the enzyme phosphodiesterase-4 (PDE-4).Reference standards of Roflumilast API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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(
    [pname] => Roflumilast - API Standards
    [catalogue_number] => PA 18 15000
    [category_ids] => ,81,78,70,82,
    [chemical_name] => 
    [weight] => 403.21
    [form] => C17H14Cl2F2N2O3
    [cas] => 162401-32-3
    [pslug] => 162401-32-3-roflumilast-api-standards-pa1815000
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    [offers_product_code] => PA 18 15000
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PA 18 15000

Roflumilast - API Standards


  • Catalogue No.:PA 18 15000

  • CAS :

    162401-32-3

  • Molecular Formula : C17H14Cl2F2N2O3

  • Molecular Weight : 403.21

20 % OFF
stdClass Object
(
    [pname] => Roflumilast N-Oxide
    [catalogue_number] => PA 18 15530
    [category_ids] => 82,81,78,76,75,71,70
    [chemical_name] => 
    [weight] => 419.21
    [form] => C17H14Cl2F2N2O4
    [cas] => 292135-78-5
    [pslug] => 292135-78-5-roflumilast-n-oxide-pa1815530
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    [offers_product_code] => PA 18 15530
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PA 18 15530

Roflumilast N-Oxide


  • Catalogue No.:PA 18 15530

  • CAS :

    292135-78-5

  • Molecular Formula : C17H14Cl2F2N2O4

  • Molecular Weight : 419.21

20 % OFF
stdClass Object
(
    [pname] => 5-Dechloro Roflumilast
    [catalogue_number] => PA 18 15510
    [category_ids] => ,71,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 368.76
    [form] => C17H15ClF2N2O3
    [cas] => 1391053-75-0
    [pslug] => 1391053-75-0-5-dechloro-roflumilast-pa1815510
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PA 18 15510

5-Dechloro Roflumilast


  • Catalogue No.:PA 18 15510

  • CAS :

    1391053-75-0

  • Molecular Formula : C17H15ClF2N2O3

  • Molecular Weight : 368.76

stdClass Object
(
    [pname] => 3-O-Decyclopropyl Roflumilast
    [catalogue_number] => PA 18 15520
    [category_ids] => 81,80,71,70,75,78,82
    [chemical_name] => 
    [weight] => 349.12
    [form] => C13H8Cl2F2N2O3
    [cas] => 1391052-76-8
    [pslug] => 1391052-76-8-3-o-decyclopropyl-roflumilast-pa1815520
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PA 18 15520

3-O-Decyclopropyl Roflumilast


  • Catalogue No.:PA 18 15520

  • CAS :

    1391052-76-8

  • Molecular Formula : C13H8Cl2F2N2O3

  • Molecular Weight : 349.12

stdClass Object
(
    [pname] => 4-Amino-3,5-dichloropyridine
    [catalogue_number] => PA 18 15550
    [category_ids] => 79,82,78,70,71,80
    [chemical_name] => 
    [weight] => 163
    [form] => C5H4Cl2N2
    [cas] => 22889-78-7
    [pslug] => 22889-78-7-4-amino-3-5-dichloropyridine-pa1815550
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PA 18 15550

4-Amino-3,5-dichloropyridine


  • Catalogue No.:PA 18 15550

  • CAS :

    22889-78-7

  • Molecular Formula : C5H4Cl2N2

  • Molecular Weight : 163

stdClass Object
(
    [pname] => 3-(Cyclobutoxy-N-(3,5-dichloropyridin-4-yl))-4-(difluoromethoxy)benzamide
    [catalogue_number] => PA 18 15560
    [category_ids] => 81,82,78,70
    [chemical_name] => 
    [weight] => 403.21
    [form] => C17H14Cl2F2N2O3
    [cas] => 2368178-28-1
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PA 18 15560

3-(Cyclobutoxy-N-(3,5-dichloropyridin-4-yl))-4-(difluoromethoxy)benzamide


  • Catalogue No.:PA 18 15560

  • CAS :

    2368178-28-1

  • Molecular Formula : C17H14Cl2F2N2O3

  • Molecular Weight : 403.21

stdClass Object
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    [pname] => 3,4-Di(cyclopropylmethoxy) Roflumilast
    [catalogue_number] => PA 18 15570
    [category_ids] => ,80,71,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 407.29
    [form] => C20H20Cl2N2O3
    [cas] => 1391052-24-6
    [pslug] => 1391052-24-6-3-4-di-cyclopropylmethoxy-roflumilast-pa1815570
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PA 18 15570

3,4-Di(cyclopropylmethoxy) Roflumilast


  • Catalogue No.:PA 18 15570

  • CAS :

    1391052-24-6

  • Molecular Formula : C20H20Cl2N2O3

  • Molecular Weight : 407.29

stdClass Object
(
    [pname] => 4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast
    [catalogue_number] => PA 18 15580
    [category_ids] => ,80,71,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 403.21
    [form] => C17H14Cl2F2N2O3
    [cas] => 162401-43-6
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PA 18 15580

4-(Cyclopropylmethoxy)-3-(difluoromethoxy) Roflumilast


  • Catalogue No.:PA 18 15580

  • CAS :

    162401-43-6

  • Molecular Formula : C17H14Cl2F2N2O3

  • Molecular Weight : 403.21

stdClass Object
(
    [pname] => 3,4-bis(Difluoromethoxy) Roflumilast
    [catalogue_number] => PA 18 15590
    [category_ids] => ,80,71,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 399.12
    [form] => C14H8Cl2F4N2O3
    [cas] => 162401-30-1
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PA 18 15590

3,4-bis(Difluoromethoxy) Roflumilast


  • Catalogue No.:PA 18 15590

  • CAS :

    162401-30-1

  • Molecular Formula : C14H8Cl2F4N2O3

  • Molecular Weight : 399.12

stdClass Object
(
    [pname] => N-(3,5-Dichloro-4-pyridinyl)-3,4-Dihydroxybenzamide
    [catalogue_number] => PA 18 15600
    [category_ids] => ,81,78,70,82,
    [chemical_name] => 
    [weight] => 299.11
    [form] => C12H8Cl2N2O3
    [cas] => 1412448-29-3
    [pslug] => 1412448-29-3-n-3-5-dichloro-4-pyridinyl-3-4-dihydroxybenzamide-pa1815600
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PA 18 15600

N-(3,5-Dichloro-4-pyridinyl)-3,4-Dihydroxybenzamide


  • Catalogue No.:PA 18 15600

  • CAS :

    1412448-29-3

  • Molecular Formula : C12H8Cl2N2O3

  • Molecular Weight : 299.11

stdClass Object
(
    [pname] => 3-Cyclobutyl-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
    [catalogue_number] => PA 18 15610
    [category_ids] => ,80,71,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 387.21
    [form] => C17H14Cl2F2N2O2
    [cas] => NA
    [pslug] => 3-cyclobutyl-n-3-5-dichloropyridin-4-yl-4-difluoromethoxy-benzamide-pa1815610
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PA 18 15610

3-Cyclobutyl-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide


  • Catalogue No.:PA 18 15610

  • CAS :

    NA

  • Molecular Formula : C17H14Cl2F2N2O2

  • Molecular Weight : 387.21

stdClass Object
(
    [pname] => 3-(But-3-en-1-yloxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide
    [catalogue_number] => PA 18 15620
    [category_ids] => 82,81,80,78,75,71,70
    [chemical_name] => 
    [weight] => 403.21
    [form] => C17H14Cl2F2N2O3
    [cas] => 2368178-29-2
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PA 18 15620

3-(But-3-en-1-yloxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide


  • Catalogue No.:PA 18 15620

  • CAS :

    2368178-29-2

  • Molecular Formula : C17H14Cl2F2N2O3

  • Molecular Weight : 403.21

stdClass Object
(
    [pname] => 3,4-Di(cyclopropylmethoxy)-benzoic Acid
    [catalogue_number] => PA 18 15630
    [category_ids] => 82,78,70,71,80
    [chemical_name] => 
    [weight] => 262.3
    [form] => C15H18O4
    [cas] => 1369851-30-8
    [pslug] => 1369851-30-8-3-4-di-cyclopropylmethoxy-benzoic-acid-pa1815630
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PA 18 15630

3,4-Di(cyclopropylmethoxy)-benzoic Acid


  • Catalogue No.:PA 18 15630

  • CAS :

    1369851-30-8

  • Molecular Formula : C15H18O4

  • Molecular Weight : 262.3

stdClass Object
(
    [pname] => Roflumilast-d4
    [catalogue_number] => PA STI 078300
    [category_ids] => ,81,98,78,70,82,
    [chemical_name] => 
    [weight] => 407.23
    [form] => C17H11D3Cl2F2N2O3
    [cas] => 1398065-69-4
    [pslug] => 1398065-69-4-roflumilast-d4-pasti078300
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PA STI 078300

Roflumilast-d4


  • Catalogue No.:PA STI 078300

  • CAS :

    1398065-69-4

  • Molecular Formula : C17H11D3Cl2F2N2O3

  • Molecular Weight : 407.23

stdClass Object
(
    [pname] => Roflumilast-d4 N-Oxide
    [catalogue_number] => PA STI 078310
    [category_ids] => ,71,98,76,75,81,78,70,82,
    [chemical_name] => 
    [weight] => 423.23
    [form] => C17H10D4Cl2F2N2O4
    [cas] => 1794760-31-8
    [pslug] => 1794760-31-8-roflumilast-d4-n-oxide-pasti078310
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PA STI 078310

Roflumilast-d4 N-Oxide


  • Catalogue No.:PA STI 078310

  • CAS :

    1794760-31-8

  • Molecular Formula : C17H10D4Cl2F2N2O4

  • Molecular Weight : 423.23

stdClass Object
(
    [pname] => 2,3-Dichloropyridin-4-amine
    [catalogue_number] => PA 18 15670
    [category_ids] => ,82,75,78,70,82,
    [chemical_name] => 
    [weight] => 163
    [form] => C5H4Cl2N2
    [cas] => 184416-83-9
    [pslug] => 184416-83-9-2-3-dichloropyridin-4-amine-pa1815670
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PA 18 15670

2,3-Dichloropyridin-4-amine


  • Catalogue No.:PA 18 15670

  • CAS :

    184416-83-9

  • Molecular Formula : C5H4Cl2N2

  • Molecular Weight : 163

stdClass Object
(
    [pname] => 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide
    [catalogue_number] => PA 18 0151000
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 353.2
    [form] => C16H14Cl2N2O3
    [cas] => 475271-62-6
    [pslug] => 475271-62-6-3-cyclopropylmethoxy-n-3-5-dichloropyridin-4-yl-4-hydroxybenzamide-pa180151000
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PA 18 0151000

3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-hydroxybenzamide


  • Catalogue No.:PA 18 0151000

  • CAS :

    475271-62-6

  • Molecular Formula : C16H14Cl2N2O3

  • Molecular Weight : 353.2

stdClass Object
(
    [pname] => N-(3-Bromo-5-chloropyridin-4-yl)-3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamide
    [catalogue_number] => PA 18 0151001
    [category_ids] => 76,78,82,70,75
    [chemical_name] => 
    [weight] => 447.66
    [form] => C17H14BrClF2N2O3
    [cas] => 3031785-18-6
    [pslug] => 3031785-18-6-n-3-bromo-5-chloropyridin-4-yl-3-cyclopropylmethoxy-4-difluoromethoxy-benzamide-pa180151001
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PA 18 0151001

N-(3-Bromo-5-chloropyridin-4-yl)-3-(cyclopropylmethoxy)-4-(difluoromethoxy)benzamide


  • Catalogue No.:PA 18 0151001

  • CAS :

    3031785-18-6

  • Molecular Formula : C17H14BrClF2N2O3

  • Molecular Weight : 447.66

stdClass Object
(
    [pname] => 5-((3,5-Dichloropyridin-4-yl)carbamoyl)-2-(difluoromethoxy)phenyl dimethylcarbamate
    [catalogue_number] => PA 18 0151002
    [category_ids] => 76,70,75,78,82
    [chemical_name] => 
    [weight] => 420.19
    [form] => C16H13Cl2F2N3O4
    [cas] => 2048860-65-5
    [pslug] => 2048860-65-5-5-3-5-dichloropyridin-4-yl-carbamoyl-2-difluoromethoxy-phenyl-dimethylcarbamate-pa180151002
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PA 18 0151002

5-((3,5-Dichloropyridin-4-yl)carbamoyl)-2-(difluoromethoxy)phenyl dimethylcarbamate


  • Catalogue No.:PA 18 0151002

  • CAS :

    2048860-65-5

  • Molecular Formula : C16H13Cl2F2N3O4

  • Molecular Weight : 420.19

stdClass Object
(
    [pname] =>  4-(Difluoromethoxy)-3-Hydroxybenzoic Acid
    [catalogue_number] => PA 18 0151003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 204.13
    [form] => C8H6F2O4
    [cas] => 913985-07-6
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PA 18 0151003

 4-(Difluoromethoxy)-3-Hydroxybenzoic Acid


  • Catalogue No.:PA 18 0151003

  • CAS :

    913985-07-6

  • Molecular Formula : C8H6F2O4

  • Molecular Weight : 204.13

stdClass Object
(
    [pname] => Roflumilast KSM-II Bromo Compound
    [catalogue_number] => PA 18 0151004
    [category_ids] => ,81,78,70,82,
    [chemical_name] => 
    [weight] => 207.46
    [form] => C5H4BrClN2
    [cas] => 159783-78-5
    [pslug] => 159783-78-5-roflumilast-ksm-ii-bromo-compound-pa180151004
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PA 18 0151004

Roflumilast KSM-II Bromo Compound


  • Catalogue No.:PA 18 0151004

  • CAS :

    159783-78-5

  • Molecular Formula : C5H4BrClN2

  • Molecular Weight : 207.46

stdClass Object
(
    [pname] => Roflumilast Dimer
    [catalogue_number] => PA 18 0151005
    [category_ids] => ,81,78,70,82,
    [chemical_name] => 
    [weight] => 643.41
    [form] => C29H24Cl2F4N2O6
    [cas] => 1352122-37-2
    [pslug] => 1352122-37-2-roflumilast-dimer-pa180151005
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PA 18 0151005

Roflumilast Dimer


  • Catalogue No.:PA 18 0151005

  • CAS :

    1352122-37-2

  • Molecular Formula : C29H24Cl2F4N2O6

  • Molecular Weight : 643.41

stdClass Object
(
    [pname] => 3-(Cyclopropylmethoxy)-4-hydroxybenzaldehyde
    [catalogue_number] => PA 18 0151006
    [category_ids] => ,81,78,70,82,
    [chemical_name] => 
    [weight] => 192.21
    [form] => C11H12O3
    [cas] => 25934-52-5
    [pslug] => 25934-52-5-3-cyclopropylmethoxy-4-hydroxybenzaldehyde-pa180151006
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PA 18 0151006

3-(Cyclopropylmethoxy)-4-hydroxybenzaldehyde


  • Catalogue No.:PA 18 0151006

  • CAS :

    25934-52-5

  • Molecular Formula : C11H12O3

  • Molecular Weight : 192.21

stdClass Object
(
    [pname] => 3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde
    [catalogue_number] => PA 18 0151007
    [category_ids] => ,81,78,70,82,
    [chemical_name] => 
    [weight] => 242.22
    [form] => C12H12F2O3
    [cas] => 151103-09-2
    [pslug] => 151103-09-2-3-cyclopropylmethoxy-4-difluoromethoxy-benzaldehyde-pa180151007
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PA 18 0151007

3-(Cyclopropylmethoxy)-4-(difluoromethoxy)benzaldehyde


  • Catalogue No.:PA 18 0151007

  • CAS :

    151103-09-2

  • Molecular Formula : C12H12F2O3

  • Molecular Weight : 242.22

stdClass Object
(
    [pname] => 3-(Cyclopropylmethoxy)-4-hydroxybenzoic Acid
    [catalogue_number] => PA 18 0151008
    [category_ids] => ,81,78,70,82,
    [chemical_name] => 
    [weight] => 208.21
    [form] => C11H12O4
    [cas] => 1243391-44-7
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PA 18 0151008

3-(Cyclopropylmethoxy)-4-hydroxybenzoic Acid


  • Catalogue No.:PA 18 0151008

  • CAS :

    1243391-44-7

  • Molecular Formula : C11H12O4

  • Molecular Weight : 208.21

stdClass Object
(
    [pname] => N-(3,5-Dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide
    [catalogue_number] => PA 18 0151009
    [category_ids] => ,81,78,70,82,
    [chemical_name] => 
    [weight] => 363.14
    [form] => C14H10Cl2F2N2O3
    [cas] => 162401-29-8
    [pslug] => 162401-29-8-n-3-5-dichloropyridin-4-yl-4-difluoromethoxy-3-methoxybenzamide-pa180151009
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PA 18 0151009

N-(3,5-Dichloropyridin-4-yl)-4-(difluoromethoxy)-3-methoxybenzamide


  • Catalogue No.:PA 18 0151009

  • CAS :

    162401-29-8

  • Molecular Formula : C14H10Cl2F2N2O3

  • Molecular Weight : 363.14