Neratinib is used as an adjuvant therapy in people with early stage breast cancer in which HER2 is overexpressed, after the person receives treatment with trastuzumab. It is a tyrosine kinase inhibitor anticancer drug. Reference standards of Neratinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Neratinib - API Standards [catalogue_number] => PA 14 74000 [category_ids] => ,79,80,71,81,78,70,82, [chemical_name] => [weight] => 557.04 [form] => C30H29ClN6O3 [cas] => 698387-09-6 [pslug] => 698387-09-6-neratinib-api-pa1474000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 74000
CAS :
Molecular Formula : C30H29ClN6O3
Molecular Weight : 557.04
stdClass Object ( [pname] => Neratinib-d6 [catalogue_number] => PA STI 067320 [category_ids] => ,79,80,71,98,78,70,82, [chemical_name] => [weight] => 563.08 [form] => C30H23D6ClN6O3 [cas] => 1259519-18-0 [pslug] => 1259519-18-0-neratinib-d6-pasti067320 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 067320
Molecular Formula : C30H23D6ClN6O3
Molecular Weight : 563.08
stdClass Object ( [pname] => (E)-4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-6-(4-(dimethylamino)but-2-enamido)-7-ethoxyquinoline-3-carboxylic Acid [catalogue_number] => PA 14 74520 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 576.05 [form] => C30H30ClN5O5 [cas] => NA [pslug] => e-4-3-chloro-4-pyridin-2-ylmethoxy-phenyl-amino-6-4-dimethylamino-but-2-enamido-7-ethoxyquinoline-3-carboxylic-acid-pa1474520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 74520
Molecular Formula : C30H30ClN5O5
Molecular Weight : 576.05
stdClass Object ( [pname] => N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)acetamide [catalogue_number] => PA 14 74530 [category_ids] => ,70,78,82, [chemical_name] => [weight] => 473.92 [form] => C25H20ClN5O3 [cas] => 2748212-19-1 [pslug] => 2748212-19-1-n-4-3-chloro-4-pyridin-2-ylmethoxy-phenyl-amino-3-cyano-7-methoxyquinolin-6-yl-acetamide-pa1474530 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 74530
Molecular Formula : C25H20ClN5O3
Molecular Weight : 473.92
stdClass Object ( [pname] => (E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(methylamino)but-2-enamide [catalogue_number] => PA 14 74540 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 543.02 [form] => C29H27ClN6O3 [cas] => 915788-27-1 [pslug] => 915788-27-1-e-n-4-3-chloro-4-pyridin-2-ylmethoxy-phenyl-amino-3-cyano-7-ethoxyquinolin-6-yl-4-methylamino-but-2-enamide-pa1474540 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 74540
Molecular Formula : C29H27ClN6O3
Molecular Weight : 543.02
stdClass Object ( [pname] => (E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-methoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide [catalogue_number] => PA 14 74550 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 543.02 [form] => C29H27ClN6O3 [cas] => NA [pslug] => e-n-4-3-chloro-4-pyridin-2-ylmethoxy-phenyl-amino-3-cyano-7-methoxyquinolin-6-yl-4-dimethylamino-but-2-enamide-pa1474550 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 74550
stdClass Object ( [pname] => (E)-N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-hydroxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide [catalogue_number] => PA 14 74560 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 529 [form] => C28H25ClN6O3 [cas] => NA [pslug] => e-n-4-3-chloro-4-pyridin-2-ylmethoxy-phenyl-amino-3-cyano-7-hydroxyquinolin-6-yl-4-dimethylamino-but-2-enamide-pa1474560 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 74560
Molecular Formula : C28H25ClN6O3
Molecular Weight : 529
stdClass Object ( [pname] => (E)-N-(4-((3-Chloro-4-hydroxyphenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)-4-(dimethylamino)but-2-enamide [catalogue_number] => PA 14 74570 [category_ids] => ,70,78,82, [chemical_name] => [weight] => 465.94 [form] => C24H24ClN5O3 [cas] => 1895881-83-0 [pslug] => 1895881-83-0-e-n-4-3-chloro-4-hydroxyphenyl-amino-3-cyano-7-ethoxyquinolin-6-yl-4-dimethylamino-but-2-enamide-pa1474570 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 74570
Molecular Formula : C24H24ClN5O3
Molecular Weight : 465.94
stdClass Object ( [pname] => N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)formamide [catalogue_number] => PA 14 0741001 [category_ids] => ,71,81,78,70,82, [chemical_name] => [weight] => 473.92 [form] => C25H20ClN5O3 [cas] => 1144516-20-0 [pslug] => 1144516-20-0-n-4-3-chloro-4-pyridin-2-ylmethoxy-phenyl-amino-3-cyano-7-ethoxyquinolin-6-yl-formamide-pa140741001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0741001
stdClass Object ( [pname] => 6-Amino-4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-7-ethoxyquinoline-3-carbonitrile [catalogue_number] => PA 14 0741002 [category_ids] => ,71,81,78,70,82, [chemical_name] => [weight] => 445.91 [form] => C24H20ClN5O2 [cas] => 848139-78-6 [pslug] => 848139-78-6-6-amino-4-3-chloro-4-pyridin-2-ylmethoxy-phenyl-amino-7-ethoxyquinoline-3-carbonitrile-pa140741002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0741002
Molecular Formula : C24H20ClN5O2
Molecular Weight : 445.91
stdClass Object ( [pname] => Neratinib pyridine N-oxide (M3) [catalogue_number] => PA 14 0741003 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 573.05 [form] => C30H29ClN6O4 [cas] => 1376619-94-1 [pslug] => 1376619-94-1-neratinib-pyridine-n-oxide-m3-pa140741003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0741003
Molecular Formula : C30H29ClN6O4
Molecular Weight : 573.05
stdClass Object ( [pname] => Neratinib dimethylamine N-oxide (M7) [catalogue_number] => PA 14 0741004 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 573.05 [form] => C30H29ClN6O4 [cas] => 1376615-55-2 [pslug] => 1376615-55-2-neratinib-dimethylamine-n-oxide-m7-pa140741004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0741004
stdClass Object ( [pname] => N-(4-((3-Chloro-4-(pyridin-2-ylmethoxy)phenyl)amino)-3-cyano-7-ethoxyquinolin-6-yl)acetamide [catalogue_number] => PA 14 0741005 [category_ids] => ,78,70,82, [chemical_name] => [weight] => 487.94 [form] => C26H22ClN5O3 [cas] => 915941-95-6 [pslug] => 915941-95-6-n-4-3-chloro-4-pyridin-2-ylmethoxy-phenyl-amino-3-cyano-7-ethoxyquinolin-6-yl-acetamide-pa140741005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0741005
Molecular Formula : C26H22ClN5O3
Molecular Weight : 487.94
stdClass Object ( [pname] => N-Nitroso Neratinib [catalogue_number] => PA 14 0741006 [category_ids] => ,79,80,71,81,78,70,82, [chemical_name] => [weight] => 586.05 [form] => C30H28ClN7O4 [cas] => NA [pslug] => n-nitroso-neratinib-pa140741006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 14 0741006
Molecular Formula : C30H28ClN7O4
Molecular Weight : 586.05
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