lapatinib ditosylate hydrate

Pharmaceutical standards - Lapatinib Ditosylate Hydrate is used in combination therapy for HER2-positive breast cancer. It is used for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress HER2. Reference standards of Lapatinib Ditosylate Hydrate API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Lapatinib Ditosylate Hydrate
    [catalogue_number] => PA 39 05000
    [category_ids] => ,80,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 943.48
    [form] => C43H44ClFN4O11S3
    [cas] => 388082-78-8
    [pslug] => 388082-78-8-lapatinib-ditosylate-hydrate-api-pa3905000
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PA 39 05000
PA 39 05000

Lapatinib Ditosylate Hydrate

  • Catalogue No.:PA 39 05000

  • CAS :

    388082-78-8

  • Molecular Formula : C43H44ClFN4O11S3

  • Molecular Weight : 943.48

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stdClass Object
(
    [pname] => O-De(3-fluorobenzyl) Lapatinib
    [catalogue_number] => PA 39 05510
    [category_ids] => ,80,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 472.94
    [form] => C22H21ClN4O4S
    [cas] => 1268997-70-1
    [pslug] => 1268997-70-1-o-de-3-fluorobenzyl-lapatinib-pa3905510
    [latest_product] => 0
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PA 39 05510
PA 39 05510

O-De(3-fluorobenzyl) Lapatinib

  • Catalogue No.:PA 39 05510

  • CAS :

    1268997-70-1

  • Molecular Formula : C22H21ClN4O4S

  • Molecular Weight : 472.94

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stdClass Object
(
    [pname] => N-De[2-(methylsulfonyl)ethyl] Lapatinib
    [catalogue_number] => PA 39 05520
    [category_ids] => ,80,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 474.91
    [form] => C26H20ClFN4O2
    [cas] => 697299-82-4
    [pslug] => 697299-82-4-n-de-2-methylsulfonyl-ethyl-lapatinib-pa3905520
    [latest_product] => 0
    [linkproducts] => 0
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PA 39 05520
PA 39 05520

N-De[2-(methylsulfonyl)ethyl] Lapatinib

  • Catalogue No.:PA 39 05520

  • CAS :

    697299-82-4

  • Molecular Formula : C26H20ClFN4O2

  • Molecular Weight : 474.91

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stdClass Object
(
    [pname] => 5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carboxylic Acid
    [catalogue_number] => PA 39 05530
    [category_ids] => ,80,71,76,75,78,70,82,88,
    [chemical_name] => 
    [weight] => 489.88
    [form] => C26H17ClFN3O4
    [cas] => 1152131-73-1
    [pslug] => 1152131-73-1-5-4-3-chloro-4-3-fluorobenzyl-oxy-phenyl-amino-quinazolin-6-yl-furan-2-carboxylic-acid-pa3905530
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PA 39 05530
PA 39 05530

5-(4-((3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carboxylic Acid

  • Catalogue No.:PA 39 05530

  • CAS :

    1152131-73-1

  • Molecular Formula : C26H17ClFN3O4

  • Molecular Weight : 489.88

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stdClass Object
(
    [pname] => Des(sulfonylethyl)amino Hydroxy Lapatinib
    [catalogue_number] => PA 39 05540
    [category_ids] => ,80,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 475.9
    [form] => C26H19ClFN3O3
    [cas] => 320337-48-2
    [pslug] => 320337-48-2-des-sulfonylethyl-amino-hydroxy-lapatinib-pa3905540
    [latest_product] => 0
    [linkproducts] => 0
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PA 39 05540
PA 39 05540

Des(sulfonylethyl)amino Hydroxy Lapatinib

  • Catalogue No.:PA 39 05540

  • CAS :

    320337-48-2

  • Molecular Formula : C26H19ClFN3O3

  • Molecular Weight : 475.9

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Details 
stdClass Object
(
    [pname] => 5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde
    [catalogue_number] => PA 39 05550
    [category_ids] => ,70,78,70,82,
    [chemical_name] => 
    [weight] => 473.89
    [form] => C26H17ClFN3O3
    [cas] => 231278-84-5
    [pslug] => 231278-84-5-5-4-3-chloro-4-3-fluorophenyl-methoxy-phenyl-amino-6-quinazolinyl-2-furancarboxaldehyde-pa3905550
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PA 39 05550
PA 39 05550

5-[4-[[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-6-quinazolinyl]-2-furancarboxaldehyde

  • Catalogue No.:PA 39 05550

  • CAS :

    231278-84-5

  • Molecular Formula : C26H17ClFN3O3

  • Molecular Weight : 473.89

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Details 
stdClass Object
(
    [pname] => N-(3-Chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
    [catalogue_number] => PA 39 0051000
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 581.06
    [form] => C29H26ClFN4O4S
    [cas] => 1393112-45-2
    [pslug] => 1393112-45-2-n-3-chloro-4-2-fluorobenzyl-oxy-phenyl-6-5-2-methylsulfonyl-ethyl-amino-methyl-furan-2-yl-quinazolin-4-amine-pa390051000
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PA 39 0051000
PA 39 0051000

N-(3-Chloro-4-((2-fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine

  • Catalogue No.:PA 39 0051000

  • CAS :

    1393112-45-2

  • Molecular Formula : C29H26ClFN4O4S

  • Molecular Weight : 581.06

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Details 
stdClass Object
(
    [pname] => N-(4-(4-Fluorobenzyloxy)-3-chlorophenyl)-6-(5-((2-(methylsulfonyl)ethylamino) methyl)furan-2-yl)quinazolin-4-amine
    [catalogue_number] => PA 39 0051001
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 581.06
    [form] => C29H26ClFN4O4S
    [cas] => 1026818-86-9
    [pslug] => 1026818-86-9-n-4-4-fluorobenzyloxy-3-chlorophenyl-6-5-2-methylsulfonyl-ethylamino-methyl-furan-2-yl-quinazolin-4-amine-pa390051001
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PA 39 0051001
PA 39 0051001

N-(4-(4-Fluorobenzyloxy)-3-chlorophenyl)-6-(5-((2-(methylsulfonyl)ethylamino) methyl)furan-2-yl)quinazolin-4-amine

  • Catalogue No.:PA 39 0051001

  • CAS :

    1026818-86-9

  • Molecular Formula : C29H26ClFN4O4S

  • Molecular Weight : 581.06

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Details 
stdClass Object
(
    [pname] => 3-Chloro-4-(3-fluorobenzyloxy)aniline
    [catalogue_number] => PA 39 0051002
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 251.69
    [form] => C13H11ClFNO
    [cas] => 202197-26-0
    [pslug] => 202197-26-0-3-chloro-4-3-fluorobenzyloxy-aniline-pa390051002
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PA 39 0051002
PA 39 0051002

3-Chloro-4-(3-fluorobenzyloxy)aniline

  • Catalogue No.:PA 39 0051002

  • CAS :

    202197-26-0

  • Molecular Formula : C13H11ClFNO

  • Molecular Weight : 251.69

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stdClass Object
(
    [pname] => Deschloro Lapatinib
    [catalogue_number] => PA 39 0051004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 546.62
    [form] => C29H27FN4O4S
    [cas] => 633370-23-7
    [pslug] => 633370-23-7-deschloro-lapatinib-pa390051004
    [latest_product] => 1
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PA 39 0051004
PA 39 0051004

Deschloro Lapatinib

pharmaffiliates

  • Catalogue No.:PA 39 0051004

  • CAS :

    633370-23-7

  • Molecular Formula : C29H27FN4O4S

  • Molecular Weight : 546.62

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stdClass Object
(
    [pname] => N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine
    [catalogue_number] => PA 39 0051005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 505.72
    [form] => C21H14ClFIN3O
    [cas] => 231278-20-9
    [pslug] => 231278-20-9-n-3-chloro-4-3-fluorophenyl-methoxy-phenyl-6-iodo-4-quinazolinamine-pa390051005
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PA 39 0051005
PA 39 0051005

N-[3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-iodo-4-quinazolinamine

  • Catalogue No.:PA 39 0051005

  • CAS :

    231278-20-9

  • Molecular Formula : C21H14ClFIN3O

  • Molecular Weight : 505.72

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stdClass Object
(
    [pname] => N-(4-((3-Fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate)
    [catalogue_number] => PA 39 0051006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 891.01
    [form] => C43H43FN4O10S3
    [cas] => NA
    [pslug] => n-4-3-fluorobenzyl-oxy-phenyl-6-5-2-methylsulfonyl-ethyl-amino-methyl-furan-2-yl-quinazolin-4-amine-bis-4-methylbenzenesulfonate-pa390051006
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PA 39 0051006
PA 39 0051006

N-(4-((3-Fluorobenzyl)oxy)phenyl)-6-(5-(((2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine bis(4-methylbenzenesulfonate)

pharmaffiliates

  • Catalogue No.:PA 39 0051006

  • CAS :

    NA

  • Molecular Formula : C43H43FN4O10S3

  • Molecular Weight : 891.01

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stdClass Object
(
    [pname] => 4-((3-Fluorobenzyl)oxy)aniline
    [catalogue_number] => PAI 39 005001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 217.24
    [form] => C13H12FNO
    [cas] => 202197-25-9
    [pslug] => 202197-25-9-4-3-fluorobenzyl-oxy-aniline-pai39005001
    [latest_product] => 0
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PAI 39 005001
PAI 39 005001

4-((3-Fluorobenzyl)oxy)aniline

  • Catalogue No.:PAI 39 005001

  • CAS :

    202197-25-9

  • Molecular Formula : C13H12FNO

  • Molecular Weight : 217.24

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stdClass Object
(
    [pname] => 4-((3-Fluorobenzyl)oxy)aniline Hydrochloride
    [catalogue_number] => PAI 39 005002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 253.7
    [form] => C13H13ClFNO
    [cas] => 57181-87-0
    [pslug] => 57181-87-0-4-3-fluorobenzyl-oxy-aniline-hydrochloride-pai39005002
    [latest_product] => 0
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PAI 39 005002
PAI 39 005002

4-((3-Fluorobenzyl)oxy)aniline Hydrochloride

  • Catalogue No.:PAI 39 005002

  • CAS :

    57181-87-0

  • Molecular Formula : C13H13ClFNO

  • Molecular Weight : 253.7

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stdClass Object
(
    [pname] => N-(4-((3-Fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine
    [catalogue_number] => PAI 39 005003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 471.27
    [form] => C21H15FIN3O
    [cas] => 231278-25-4
    [pslug] => 231278-25-4-n-4-3-fluorobenzyl-oxy-phenyl-6-iodoquinazolin-4-amine-pai39005003
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PAI 39 005003
PAI 39 005003

N-(4-((3-Fluorobenzyl)oxy)phenyl)-6-iodoquinazolin-4-amine

  • Catalogue No.:PAI 39 005003

  • CAS :

    231278-25-4

  • Molecular Formula : C21H15FIN3O

  • Molecular Weight : 471.27

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Details 
stdClass Object
(
    [pname] => 5-(4-((4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde
    [catalogue_number] => PAI 39 005004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 439.45
    [form] => C26H18FN3O3
    [cas] => 746591-42-4
    [pslug] => 746591-42-4-5-4-4-3-fluorobenzyl-oxy-phenyl-amino-quinazolin-6-yl-furan-2-carbaldehyde-pai39005004
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PAI 39 005004
PAI 39 005004

5-(4-((4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-carbaldehyde

  • Catalogue No.:PAI 39 005004

  • CAS :

    746591-42-4

  • Molecular Formula : C26H18FN3O3

  • Molecular Weight : 439.45

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Details 
stdClass Object
(
    [pname] => N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-((((5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-yl)methyl)(2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine
    [catalogue_number] => PA 39 0051008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 1038.95
    [form] => C55H43Cl2F2N7O6S
    [cas] => 2172855-57-9
    [pslug] => 2172855-57-9-n-3-chloro-4-3-fluorobenzyl-oxy-phenyl-6-5-5-4-3-chloro-4-3-fluorobenzyl-oxy-phenyl-amino-quinazolin-6-yl-furan-2-yl-methyl-2-methylsulfonyl-ethyl-amino-methyl-furan-2-yl-quinazolin-4-amine-pa390051008
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PA 39 0051008
PA 39 0051008

N-(3-Chloro-4-((3-fluorobenzyl)oxy)phenyl)-6-(5-((((5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-yl)methyl)(2-(methylsulfonyl)ethyl)amino)methyl)furan-2-yl)quinazolin-4-amine

  • Catalogue No.:PA 39 0051008

  • CAS :

    2172855-57-9

  • Molecular Formula : C55H43Cl2F2N7O6S

  • Molecular Weight : 1038.95

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