Ivacaftor is used for the treatment of cystic fibrosis in people having one of several specific mutations in the cystic fibrosis transmembrane conductance regulator protein. It is one of the most expensive drugs. Reference standards of Ivacaftor API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Ivacaftor [catalogue_number] => PA 09 40000 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 392.49 [form] => C24H28N2O3 [cas] => 873054-44-5 [pslug] => 873054-44-5-ivacaftor-api-pa0940000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 40000
CAS :
Molecular Formula : C24H28N2O3
Molecular Weight : 392.49
stdClass Object ( [pname] => 4-Oxo-1,4-dihydroquinoline-3-carboxylic Acid [catalogue_number] => PA 09 40510 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 189.17 [form] => C10H7NO3 [cas] => 13721-01-2 [pslug] => 13721-01-2-4-oxo-1-4-dihydroquinoline-3-carboxylic-acid-pa0940510 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 40510
Molecular Formula : C10H7NO3
Molecular Weight : 189.17
stdClass Object ( [pname] => 1,4-Dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester [catalogue_number] => PA 09 40520 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 217.22 [form] => C12H11NO3 [cas] => 52980-28-6 [pslug] => 52980-28-6-1-4-dihydro-4-oxo-3-quinolinecarboxylic-acid-ethyl-ester-pa0940520 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 40520
Molecular Formula : C12H11NO3
Molecular Weight : 217.22
stdClass Object ( [pname] => diethyl 2-((phenylamino)methylene)malonate [catalogue_number] => PA 09 0401000 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 263.29 [form] => C14H17NO4 [cas] => 54535-22-7 [pslug] => 54535-22-7-diethyl-2-phenylamino-methylene-malonate-pa090401000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401000
Molecular Formula : C14H17NO4
Molecular Weight : 263.29
stdClass Object ( [pname] => De-Alkylated Ivacaftor [catalogue_number] => PA 09 0401001 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 336.39 [form] => C20H20N2O3 [cas] => 873054-39-8 [pslug] => 873054-39-8-de-alkylated-ivacaftor-pa090401001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401001
Molecular Formula : C20H20N2O3
Molecular Weight : 336.39
stdClass Object ( [pname] => Ivacaftor D4 [catalogue_number] => PA STI 089107 [category_ids] => ,98,75,76,78,70,82, [chemical_name] => [weight] => 396.52 [form] => C24H24D4N2O3 [cas] => NA [pslug] => ivacaftor-d4-pasti089107 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 089107
Molecular Formula : C24H24D4N2O3
Molecular Weight : 396.52
stdClass Object ( [pname] => 4-Hydroxyquinoline-3-carboxylic Acid [catalogue_number] => PA 09 0401002 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 189.17 [form] => C10H7NO3 [cas] => 34785-11-0 [pslug] => 34785-11-0-4-hydroxyquinoline-3-carboxylic-acid-pa090401002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401002
stdClass Object ( [pname] => Ivacaftor D18 [catalogue_number] => PA STI 089190 [category_ids] => ,98,75,76,78,70,82, [chemical_name] => [weight] => 410.61 [form] => C24H10D18N2O3 [cas] => 1413431-05-6 [pslug] => 1413431-05-6-ivacaftor-d18-pasti089190 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA STI 089190
Molecular Formula : C24H10D18N2O3
Molecular Weight : 410.61
stdClass Object ( [pname] => 2,4-Di-tert-butyl-6-nitrophenol [catalogue_number] => PA 09 0401003 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 251.33 [form] => C14H21NO3 [cas] => 20039-94-5 [pslug] => 20039-94-5-2-4-di-tert-butyl-6-nitrophenol-pa090401003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401003
Molecular Formula : C14H21NO3
Molecular Weight : 251.33
stdClass Object ( [pname] => 4-(3-((2,4-Di-tert-butyl-5-hydroxyphenyl)carbamoyl)-4-oxoquinolin-1(4H)-yl)-4-oxobutanoic Acid [catalogue_number] => PA 09 0401004 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 492.57 [form] => C28H32N2O6 [cas] => NA [pslug] => 4-3-2-4-di-tert-butyl-5-hydroxyphenyl-carbamoyl-4-oxoquinolin-1-4h-yl-4-oxobutanoic-acid-pa090401004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401004
Molecular Formula : C28H32N2O6
Molecular Weight : 492.57
stdClass Object ( [pname] => 1-Nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylic Acid [catalogue_number] => PA 09 0401005 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 218.17 [form] => C10H6N2O4 [cas] => NA [pslug] => 1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxylic-acid-pa090401005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401005
Molecular Formula : C10H6N2O4
Molecular Weight : 218.17
stdClass Object ( [pname] => 2,4-Di-tert-butyl-5-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl 4-oxo-1,4-dihydroquinoline-3-carboxylate [catalogue_number] => PA 09 0401006 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 563.65 [form] => C34H33N3O5 [cas] => 2760759-55-3 [pslug] => 2760759-55-3-2-4-di-tert-butyl-5-4-oxo-1-4-dihydroquinoline-3-carboxamido-phenyl-4-oxo-1-4-dihydroquinoline-3-carboxylate-pa090401006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401006
Molecular Formula : C34H33N3O5
Molecular Weight : 563.65
stdClass Object ( [pname] => N-(4-(Tert-butyl)-3-hydroxyphenyl)-1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxamide [catalogue_number] => PA 09 0401007 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 365.39 [form] => C20H19N3O4 [cas] => NA [pslug] => n-4-tert-butyl-3-hydroxyphenyl-1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxamide-pa090401007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401007
Molecular Formula : C20H19N3O4
Molecular Weight : 365.39
stdClass Object ( [pname] => Ivacaftor Nitroso Impurity [catalogue_number] => PA 09 0401008 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 421.5 [form] => C24H27N3O4 [cas] => NA [pslug] => ivacaftor-nitroso-impurity-pa090401008 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401008
Molecular Formula : C24H27N3O4
Molecular Weight : 421.5
stdClass Object ( [pname] => 5-Amino-2,4-di-tert-butylphenyl methyl carbonate [catalogue_number] => PA 09 0401009 [category_ids] => ,80,78,82, [chemical_name] => [weight] => 279.38 [form] => C16H25NO3 [cas] => 1182822-31-6 [pslug] => 1182822-31-6-5-amino-2-4-di-tert-butylphenyl-methyl-carbonate-pa090401009 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401009
Molecular Formula : C16H25NO3
Molecular Weight : 279.38
stdClass Object ( [pname] => N-Nitroso Ivacaftor Ortho Isomer [catalogue_number] => PA 09 0401010 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 421.5 [form] => C24H27N3O4 [cas] => NA [pslug] => n-nitroso-ivacaftor-ortho-isomer-pa090401010 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401010
stdClass Object ( [pname] => Ethyl 1-nitroso-4-oxo-1,4-dihydroquinoline-3-carboxylate [catalogue_number] => PA 09 0401011 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 246.22 [form] => C12H10N2O4 [cas] => NA [pslug] => ethyl-1-nitroso-4-oxo-1-4-dihydroquinoline-3-carboxylate-pa090401011 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401011
Molecular Formula : C12H10N2O4
Molecular Weight : 246.22
stdClass Object ( [pname] => 2,4-Di-tert-butyl-6-nitrophenyl methyl carbonate [catalogue_number] => PA 09 0401012 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 309.36 [form] => C16H23NO5 [cas] => 873055-56-2 [pslug] => 873055-56-2-2-4-di-tert-butyl-6-nitrophenyl-methyl-carbonate-pa090401012 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401012
Molecular Formula : C16H23NO5
Molecular Weight : 309.36
stdClass Object ( [pname] => Diethyl 2-((nitroso(phenyl)amino)methylene)malonate [catalogue_number] => PA 09 0401013 [category_ids] => ,78,70,82,162, [chemical_name] => [weight] => 292.29 [form] => C14H16N2O5 [cas] => NA [pslug] => diethyl-2-nitroso-phenyl-amino-methylene-malonate-pa090401013 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401013
Molecular Formula : C14H16N2O5
Molecular Weight : 292.29
stdClass Object ( [pname] => N-(4,6-Di-tert-butyl-3-hydroxy-2-nitrosophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide [catalogue_number] => PA 09 0401014 [category_ids] => ,70,78,80,82,162, [chemical_name] => [weight] => 421.5 [form] => C24H27N3O4 [cas] => NA [pslug] => n-4-6-di-tert-butyl-3-hydroxy-2-nitrosophenyl-4-oxo-1-4-dihydroquinoline-3-carboxamide-pa090401014 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401014
stdClass Object ( [pname] => Ivacaftor Amine Impurity [catalogue_number] => PA 09 0401015 [category_ids] => ,80,78,70,82, [chemical_name] => [weight] => 392.5 [form] => C24H28N2O3 [cas] => 2760759-58-6 [pslug] => 2760759-58-6-ivacaftor-amine-impurity-pa090401015 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 09 0401015
Molecular Weight : 392.5
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