Fosaprepitant Dimeglumine-impurities | Pharmaffiliates

fosaprepitant dimeglumine

Fosaprepitant Dimeglumine is aids in the prevention of acute and delayed nausea and vomiting associated with chemotherapy treatment. It is an intravenously administered antiemetic drug. It is a prodrug of Aprepitant. Reference standards of Fosaprepitant Dimeglumine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Fosaprepitant Dimeglumine - API Standards 
    [catalogue_number] => PA 06 94000
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    [weight] => 1004.83
    [form] => C37H56F7N6O16P
    [cas] => 265121-04-8
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PA 06 94000

Fosaprepitant Dimeglumine - API Standards


  • Catalogue No.:PA 06 94000

  • CAS :

    265121-04-8

  • Molecular Formula : C37H56F7N6O16P

  • Molecular Weight : 1004.83

stdClass Object
(
    [pname] => Aprepitant
    [catalogue_number] => PA 06 94510
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 534.43
    [form] => C23H21F7N4O3
    [cas] => 170729-80-3
    [pslug] => 170729-80-3-aprepitant-pa0694510
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PA 06 94510

Aprepitant


  • Catalogue No.:PA 06 94510

  • CAS :

    170729-80-3

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

stdClass Object
(
    [pname] => N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant
    [catalogue_number] => PA 06 94520
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 566.47
    [form] => C24H25F7N4O4
    [cas] => 219821-37-1
    [pslug] => 219821-37-1-n-destriazolonomethyl-n-methylcarboxyacetamidohydrazono-aprepitant-pa0694520
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PA 06 94520

N-(Destriazolonomethyl) N-(Methylcarboxyacetamidohydrazono) Aprepitant


  • Catalogue No.:PA 06 94520

  • CAS :

    219821-37-1

  • Molecular Formula : C24H25F7N4O4

  • Molecular Weight : 566.47

stdClass Object
(
    [pname] => Fosaprepitant Dimeglumine Dibenzylester Impurity
    [catalogue_number] => PA 06 94530
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 794.65
    [form] => C37H34F7N4O6P
    [cas] => 265121-01-5
    [pslug] => 265121-01-5-fosaprepitant-dimeglumine-dibenzylester-impurity-pa0694530
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PA 06 94530

Fosaprepitant Dimeglumine Dibenzylester Impurity


  • Catalogue No.:PA 06 94530

  • CAS :

    265121-01-5

  • Molecular Formula : C37H34F7N4O6P

  • Molecular Weight : 794.65

stdClass Object
(
    [pname] => Fosaprepitant (R,R,R)-Isomer
    [catalogue_number] => PA 06 94540
    [category_ids] => 82,78,71,70,69
    [chemical_name] => 
    [weight] => 1004.83
    [form] => C37H56F7N6O16P
    [cas] => 1523569-90-5
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PA 06 94540

Fosaprepitant (R,R,R)-Isomer


  • Catalogue No.:PA 06 94540

  • CAS :

    1523569-90-5

  • Molecular Formula : C37H56F7N6O16P

  • Molecular Weight : 1004.83

stdClass Object
(
    [pname] => Fosaprepitant Desfluoro Impurity
    [catalogue_number] => PA 06 94550
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 596.42
    [form] => C23H23F6N4O6P
    [cas] => NA
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PA 06 94550

Fosaprepitant Desfluoro Impurity


  • Catalogue No.:PA 06 94550

  • CAS :

    NA

  • Molecular Formula : C23H23F6N4O6P

  • Molecular Weight : 596.42

stdClass Object
(
    [pname] => Fosaprepitant Enantiomer
    [catalogue_number] => PA 06 94560
    [category_ids] => 69,70,71,78,82
    [chemical_name] => 
    [weight] => 614.41
    [form] => C23H22F7N4O6P
    [cas] => 1523569-86-9
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PA 06 94560

Fosaprepitant Enantiomer


  • Catalogue No.:PA 06 94560

  • CAS :

    1523569-86-9

  • Molecular Formula : C23H22F7N4O6P

  • Molecular Weight : 614.41

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(
    [pname] => 3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one
    [catalogue_number] => PA 06 94570
    [category_ids] => 82,78,71,70,69
    [chemical_name] => 
    [weight] => 534.43
    [form] => C23H21F7N4O3
    [cas] => NA
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PA 06 94570

3-(((2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-1H-1,2,4-triazol-5(4H)-one


  • Catalogue No.:PA 06 94570

  • CAS :

    NA

  • Molecular Formula : C23H21F7N4O3

  • Molecular Weight : 534.43

stdClass Object
(
    [pname] => (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)
    [catalogue_number] => PA 06 94580
    [category_ids] => ,69,71,78,70,82,
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    [weight] => 1004.83
    [form] => C37H56F7N6O16P
    [cas] => NA
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PA 06 94580

(2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)


  • Catalogue No.:PA 06 94580

  • CAS :

    NA

  • Molecular Formula : C37H56F7N6O16P

  • Molecular Weight : 1004.83

stdClass Object
(
    [pname] => Fosaprepitant Dimeglumine Desfluoro Impurity
    [catalogue_number] => PA 06 94590
    [category_ids] => 82,78,71,70,69
    [chemical_name] => 
    [weight] => 986.84
    [form] => C37H57F6N6O16P
    [cas] => NA
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PA 06 94590

Fosaprepitant Dimeglumine Desfluoro Impurity


  • Catalogue No.:PA 06 94590

  • CAS :

    NA

  • Molecular Formula : C37H57F6N6O16P

  • Molecular Weight : 986.84

stdClass Object
(
    [pname] => (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)
    [catalogue_number] => PA 06 94600
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    [weight] => 1004.83
    [form] => C37H56F7N6O16P
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PA 06 94600

(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2R,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)


  • Catalogue No.:PA 06 94600

  • CAS :

    NA

  • Molecular Formula : C37H56F7N6O16P

  • Molecular Weight : 1004.83

stdClass Object
(
    [pname] => Methyl (E)-2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate
    [catalogue_number] => PA 06 94610
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 566.48
    [form] => C24H25F7N4O4
    [cas] => NA
    [pslug] => methyl-e-2-1-amino-2-2r-3s-2-r-1-3-5-bis-trifluoromethyl-phenyl-ethoxy-3-4-fluorophenyl-morpholino-ethylidene-hydrazine-1-carboxylate-pa0694610
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PA 06 94610

Methyl (E)-2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate


  • Catalogue No.:PA 06 94610

  • CAS :

    NA

  • Molecular Formula : C24H25F7N4O4

  • Molecular Weight : 566.48

stdClass Object
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    [pname] => (1’S,2R,3S)-Fosaprepitant Dimeglumine
    [catalogue_number] => PA 06 94620
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    [weight] => 1004.84
    [form] => C37H56F7N6O16P
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PA 06 94620

(1’S,2R,3S)-Fosaprepitant Dimeglumine


  • Catalogue No.:PA 06 94620

  • CAS :

    NA

  • Molecular Formula : C37H56F7N6O16P

  • Molecular Weight : 1004.84

stdClass Object
(
    [pname] => (4-Benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(p-tolyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
    [catalogue_number] => PA 06 94630
    [category_ids] => ,78,70,82,
    [chemical_name] => 
    [weight] => 700.58
    [form] => C31H31F6N4O6P
    [cas] => NA
    [pslug] => 4-benzyl-3-2r-3s-2-r-1-3-5-bis-trifluoromethyl-phenyl-ethoxy-3-p-tolyl-morpholino-methyl-5-oxo-4-5-dihydro-1h-1-2-4-triazol-1-yl-phosphonic-acid-pa0694630
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PA 06 94630

(4-Benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(p-tolyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid


  • Catalogue No.:PA 06 94630

  • CAS :

    NA

  • Molecular Formula : C31H31F6N4O6P

  • Molecular Weight : 700.58

stdClass Object
(
    [pname] => Fosaprepitant N-oxide
    [catalogue_number] => PA 06 94640
    [category_ids] => ,80,69,78,70,82,72,
    [chemical_name] => 
    [weight] => 630.41
    [form] => C23H22F7N4O7P
    [cas] => NA
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PA 06 94640

Fosaprepitant N-oxide


  • Catalogue No.:PA 06 94640

  • CAS :

    NA

  • Molecular Formula : C23H22F7N4O7P

  • Molecular Weight : 630.41

stdClass Object
(
    [pname] => Methyl (Z)-2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate
    [catalogue_number] => PA 06 94650
    [category_ids] => ,78,82,70,
    [chemical_name] => 
    [weight] => 566.48
    [form] => C24H25F7N4O4
    [cas] => 1803189-49-2
    [pslug] => 1803189-49-2-methyl-z-2-1-amino-2-2r-3s-2-r-1-3-5-bis-trifluoromethyl-phenyl-ethoxy-3-4-fluorophenyl-morpholino-ethylidene-hydrazine-1-carboxylate-pa0694650
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PA 06 94650

Methyl (Z)-2-(1-amino-2-((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)ethylidene)hydrazine-1-carboxylate


  • Catalogue No.:PA 06 94650

  • CAS :

    1803189-49-2

  • Molecular Formula : C24H25F7N4O4

  • Molecular Weight : 566.48

stdClass Object
(
    [pname] => (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)
    [catalogue_number] => PA 06 0941000
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    [weight] => 1004.84
    [form] => C37H56F7N6O16P
    [cas] => 1523569-87-0
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PA 06 0941000

(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2S,3R)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)


  • Catalogue No.:PA 06 0941000

  • CAS :

    1523569-87-0

  • Molecular Formula : C37H56F7N6O16P

  • Molecular Weight : 1004.84

stdClass Object
(
    [pname] => (3-(((2S,3R)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
    [catalogue_number] => PA 06 0941001
    [category_ids] => ,78,75,70,76,82,
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PA 06 0941001

(3-(((2S,3R)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid


  • Catalogue No.:PA 06 0941001

  • CAS :

    1185503-00-7

  • Molecular Formula : C23H22F7N4O6P

  • Molecular Weight : 614.41

stdClass Object
(
    [pname] => (3-(((2R,3S)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
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PA 06 0941002

(3-(((2R,3S)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid


  • Catalogue No.:PA 06 0941002

  • CAS :

    NA

  • Molecular Formula : C23H22F7N4O6P

  • Molecular Weight : 614.41

stdClass Object
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    [pname] => (1’S,2R,3R)-Fosaprepitant Dimeglumine
    [catalogue_number] => PA 06 0941003
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    [chemical_name] => 
    [weight] => 1004.84
    [form] => C37H56F7N6O16P
    [cas] => 1523569-88-1
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PA 06 0941003

(1’S,2R,3R)-Fosaprepitant Dimeglumine


  • Catalogue No.:PA 06 0941003

  • CAS :

    1523569-88-1

  • Molecular Formula : C37H56F7N6O16P

  • Molecular Weight : 1004.84

stdClass Object
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    [pname] => (3-(((2R,3R)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
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PA 06 0941004

(3-(((2R,3R)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid


  • Catalogue No.:PA 06 0941004

  • CAS :

    1523569-89-2

  • Molecular Formula : C23H22F7N4O6P

  • Molecular Weight : 614.41

stdClass Object
(
    [pname] => (3-(((2S,3S)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
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PA 06 0941005

(3-(((2S,3S)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid


  • Catalogue No.:PA 06 0941005

  • CAS :

    NA

  • Molecular Formula : C23H22F7N4O6P

  • Molecular Weight : 614.41

stdClass Object
(
    [pname] => (2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)
    [catalogue_number] => PA 06 0941006
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    [weight] => 1004.84
    [form] => C37H56F7N6O16P
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PA 06 0941006

(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentaol hemi((3-(((2S,3S)-2-((S)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonate)


  • Catalogue No.:PA 06 0941006

  • CAS :

    NA

  • Molecular Formula : C37H56F7N6O16P

  • Molecular Weight : 1004.84

stdClass Object
(
    [pname] => (3-(((2R,3R)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
    [catalogue_number] => PA 06 0941007
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    [weight] => 614.41
    [form] => C23H22F7N4O6P
    [cas] => NA
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PA 06 0941007

(3-(((2R,3R)-2-((S)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid


  • Catalogue No.:PA 06 0941007

  • CAS :

    NA

  • Molecular Formula : C23H22F7N4O6P

  • Molecular Weight : 614.41

stdClass Object
(
    [pname] => (3-(((2S,3S)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid
    [catalogue_number] => PA 06 0941008
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    [weight] => 614.41
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PA 06 0941008

(3-(((2S,3S)-2-((R)-1-(3,5-bis(Trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic Acid


  • Catalogue No.:PA 06 0941008

  • CAS :

    172822-01-4

  • Molecular Formula : C23H22F7N4O6P

  • Molecular Weight : 614.41

stdClass Object
(
    [pname] => (4-Benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid
    [catalogue_number] => PA 06 0941009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 704.54
    [form] => C30H28F7N4O6P
    [cas] => 2035475-10-4
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PA 06 0941009

(4-Benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid


  • Catalogue No.:PA 06 0941009

  • CAS :

    2035475-10-4

  • Molecular Formula : C30H28F7N4O6P

  • Molecular Weight : 704.54

stdClass Object
(
    [pname] => (4-Benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid Dimeglumine Salt
    [catalogue_number] => PA 06 0941010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 1094.97
    [form] => C44H62F7N6O16P
    [cas] => 2035475-11-5
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PA 06 0941010

(4-Benzyl-3-(((2R,3S)-2-((R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)morpholino)methyl)-5-oxo-4,5-dihydro-1H-1,2,4-triazol-1-yl)phosphonic acid Dimeglumine Salt


  • Catalogue No.:PA 06 0941010

  • CAS :

    2035475-11-5

  • Molecular Formula : C44H62F7N6O16P

  • Molecular Weight : 1094.97

stdClass Object
(
    [pname] => Fosaprepitant Desfluoro Impurity Meglumine Salt
    [catalogue_number] => PA 06 0941011
    [category_ids] => ,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 791.64
    [form] => C30H40F6N5O11P
    [cas] => NA
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PA 06 0941011

Fosaprepitant Desfluoro Impurity Meglumine Salt


  • Catalogue No.:PA 06 0941011

  • CAS :

    NA

  • Molecular Formula : C30H40F6N5O11P

  • Molecular Weight : 791.64