Ensifentrine

Ensifentrine, sold under the brand name Ohtuvayre, is a medication used for the treatment of chronic obstructive pulmonary disease. A drug used to treat a chronic inflammatory lung disease in adults that causes obstructed airflow. Reference standards of Ensifentrine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Ensifentrine
    [catalogue_number] => PA 05 2270000
    [category_ids] => 82,78,70
    [chemical_name] => 
    [weight] => 477.57
    [form] => C26H31N5O4
    [cas] => 1884461-72-6
    [pslug] => 1884461-72-6-ensifentrine-api-standards-pa052270000
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PA 05 2270000

Ensifentrine


  • Catalogue No.:PA 05 2270000

  • CAS :

    1884461-72-6

  • Molecular Formula : C26H31N5O4

  • Molecular Weight : 477.57

stdClass Object
(
    [pname] => 2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one
    [catalogue_number] => PA 05 2271000
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 391.47
    [form] => C23H25N3O3
    [cas] => 76536-66-8
    [pslug] => 76536-66-8-2-mesitylamino-9-10-dimethoxy-6-7-dihydro-4h-pyrimido-6-1-a-isoquinolin-4-one-pa052271000
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PA 05 2271000

2-(Mesitylamino)-9,10-dimethoxy-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one


  • Catalogue No.:PA 05 2271000

  • CAS :

    76536-66-8

  • Molecular Formula : C23H25N3O3

  • Molecular Weight : 391.47

stdClass Object
(
    [pname] => Ensifentrine-D6
    [catalogue_number] => PA STI 089850
    [category_ids] => ,98,70,78,82,
    [chemical_name] => 
    [weight] => 483.6
    [form] => C26H25D6N5O4
    [cas] => NA
    [pslug] => ensifentrine-d6-pasti089850
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PA STI 089850

Ensifentrine-D6


  • Catalogue No.:PA STI 089850

  • CAS :

    NA

  • Molecular Formula : C26H25D6N5O4

  • Molecular Weight : 483.6

stdClass Object
(
    [pname] => 9-Hydroxy Ensifentrine Impurity
    [catalogue_number] => PA 05 2271001
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 463.54
    [form] => C25H29N5O4
    [cas] => 3067475-18-4
    [pslug] => 3067475-18-4-9-hydroxy-ensifentrine-impurity-pa052271001
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PA 05 2271001

9-Hydroxy Ensifentrine Impurity


  • Catalogue No.:PA 05 2271001

  • CAS :

    3067475-18-4

  • Molecular Formula : C25H29N5O4

  • Molecular Weight : 463.54

stdClass Object
(
    [pname] => 10-Hydroxy Ensifentrine Impurity
    [catalogue_number] => PA 05 2271002
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 463.54
    [form] => C25H29N5O4
    [cas] => 3067475-19-5
    [pslug] => 3067475-19-5-10-hydroxy-ensifentrine-impurity-pa052271002
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PA 05 2271002

10-Hydroxy Ensifentrine Impurity


  • Catalogue No.:PA 05 2271002

  • CAS :

    3067475-19-5

  • Molecular Formula : C25H29N5O4

  • Molecular Weight : 463.54

stdClass Object
(
    [pname] => 1-(3,4-Dimethoxyphenethyl)pyrimidine-2,4,6(1H,3H,5H)-trione
    [catalogue_number] => PA 05 2271003
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 292.29
    [form] => C14H16N2O5
    [cas] => 75535-95-4
    [pslug] => 75535-95-4-1-3-4-dimethoxyphenethyl-pyrimidine-2-4-6-1h-3h-5h-trione-pa052271003
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PA 05 2271003

1-(3,4-Dimethoxyphenethyl)pyrimidine-2,4,6(1H,3H,5H)-trione


  • Catalogue No.:PA 05 2271003

  • CAS :

    75535-95-4

  • Molecular Formula : C14H16N2O5

  • Molecular Weight : 292.29

stdClass Object
(
    [pname] => Ensifentrine Isoindole-1,3-dione Impurity
    [catalogue_number] => PA 05 2271004
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 564.64
    [form] => C33H32N4O5
    [cas] => 3046226-90-5
    [pslug] => 3046226-90-5-ensifentrine-isoindole-1-3-dione-impurity-pa052271004
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PA 05 2271004

Ensifentrine Isoindole-1,3-dione Impurity


  • Catalogue No.:PA 05 2271004

  • CAS :

    3046226-90-5

  • Molecular Formula : C33H32N4O5

  • Molecular Weight : 564.64

stdClass Object
(
    [pname] => N-Nitroso Ensifentrine
    [catalogue_number] => PA 05 2271005
    [category_ids] => ,70,78,82,162,
    [chemical_name] => 
    [weight] => 506.56
    [form] => C26H30N6O5
    [cas] => NA
    [pslug] => n-nitroso-ensifentrine-pa052271005
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PA 05 2271005

N-Nitroso Ensifentrine


  • Catalogue No.:PA 05 2271005

  • CAS :

    NA

  • Molecular Formula : C26H30N6O5

  • Molecular Weight : 506.56

stdClass Object
(
    [pname] => Ensifentrine Dimer Impurity
    [catalogue_number] => PA 05 2271006
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 895.07
    [form] => C51H58N8O7
    [cas] => 3067475-16-2
    [pslug] => 3067475-16-2-ensifentrine-dimer-impurity-pa052271006
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PA 05 2271006

Ensifentrine Dimer Impurity


  • Catalogue No.:PA 05 2271006

  • CAS :

    3067475-16-2

  • Molecular Formula : C51H58N8O7

  • Molecular Weight : 895.07

stdClass Object
(
    [pname] => (E/Z)-Ensifentrine
    [catalogue_number] => PA 05 2271007
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 477.57
    [form] => C26H31N5O4
    [cas] => 298680-25-8
    [pslug] => 298680-25-8-e-z-ensifentrine-pa052271007
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PA 05 2271007

(E/Z)-Ensifentrine


  • Catalogue No.:PA 05 2271007

  • CAS :

    298680-25-8

  • Molecular Formula : C26H31N5O4

  • Molecular Weight : 477.57

stdClass Object
(
    [pname] => 1-(4-Hydroxy-3-methoxyphenethyl)pyrimidine-2,4,6(1H,3H,5H)-trione
    [catalogue_number] => PA 05 2271008
    [category_ids] => ,70,78,82,
    [chemical_name] => 
    [weight] => 278.26
    [form] => C13H14N2O5
    [cas] => NA
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PA 05 2271008

1-(4-Hydroxy-3-methoxyphenethyl)pyrimidine-2,4,6(1H,3H,5H)-trione


  • Catalogue No.:PA 05 2271008

  • CAS :

    NA

  • Molecular Formula : C13H14N2O5

  • Molecular Weight : 278.26

stdClass Object
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    [pname] => 1-(3-Hydroxy-4-methoxyphenethyl)pyrimidine-2,4,6(1H,3H,5H)-trione
    [catalogue_number] => PA 05 2271009
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    [chemical_name] => 
    [weight] => 278.26
    [form] => C13H14N2O5
    [cas] => NA
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PA 05 2271009

1-(3-Hydroxy-4-methoxyphenethyl)pyrimidine-2,4,6(1H,3H,5H)-trione


  • Catalogue No.:PA 05 2271009

  • CAS :

    NA

  • Molecular Formula : C13H14N2O5

  • Molecular Weight : 278.26

stdClass Object
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    [pname] => (E)-3-(2-Aminoethyl)-2-(mesitylimino)-9,10-dimethoxy-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one
    [catalogue_number] => PA 05 2271010
    [category_ids] => ,82,78,70,
    [chemical_name] => 
    [weight] => 434.54
    [form] => C25H30N4O3
    [cas] => 3046226-91-6
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PA 05 2271010

(E)-3-(2-Aminoethyl)-2-(mesitylimino)-9,10-dimethoxy-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one


  • Catalogue No.:PA 05 2271010

  • CAS :

    3046226-91-6

  • Molecular Formula : C25H30N4O3

  • Molecular Weight : 434.54

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    [pname] => (E)-1-(2-(10-Hydroxy-2-(mesitylimino)-9-methoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea
    [catalogue_number] => PA 05 2271011
    [category_ids] => ,82,78,70,
    [chemical_name] => 
    [weight] => 463.54
    [form] => C25H29N5O4
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PA 05 2271011

(E)-1-(2-(10-Hydroxy-2-(mesitylimino)-9-methoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea


  • Catalogue No.:PA 05 2271011

  • CAS :

    NA

  • Molecular Formula : C25H29N5O4

  • Molecular Weight : 463.54

stdClass Object
(
    [pname] => (E)-1-(2-(9-Hydroxy-2-(mesitylimino)-10-methoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea
    [catalogue_number] => PA 05 2271012
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    [chemical_name] => 
    [weight] => 463.54
    [form] => C25H29N5O4
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PA 05 2271012

(E)-1-(2-(9-Hydroxy-2-(mesitylimino)-10-methoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea


  • Catalogue No.:PA 05 2271012

  • CAS :

    NA

  • Molecular Formula : C25H29N5O4

  • Molecular Weight : 463.54

stdClass Object
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    [catalogue_number] => PA 05 2271013
    [category_ids] => ,82,78,70,
    [chemical_name] => 
    [weight] => 391.47
    [form] => C23H25N3O3
    [cas] => 3082769-57-8
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PA 05 2271013

(E)-2-(Mesitylimino)-9,10-dimethoxy-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one


  • Catalogue No.:PA 05 2271013

  • CAS :

    3082769-57-8

  • Molecular Formula : C23H25N3O3

  • Molecular Weight : 391.47

stdClass Object
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    [pname] => Ensifentrine Biuret Impurity
    [catalogue_number] => PA 05 2271014
    [category_ids] => ,82,78,70,
    [chemical_name] => 
    [weight] => 520.59
    [form] => C27H32N6O5
    [cas] => NA
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PA 05 2271014

Ensifentrine Biuret Impurity


  • Catalogue No.:PA 05 2271014

  • CAS :

    NA

  • Molecular Formula : C27H32N6O5

  • Molecular Weight : 520.59

stdClass Object
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    [pname] => 1,3-Bis(2-((E)-2-(mesitylimino)-9,10-dimethoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea
    [catalogue_number] => PA 05 2271015
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    [chemical_name] => 
    [weight] => 895.07
    [form] => C51H58N8O7
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PA 05 2271015

1,3-Bis(2-((E)-2-(mesitylimino)-9,10-dimethoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)urea


  • Catalogue No.:PA 05 2271015

  • CAS :

    NA

  • Molecular Formula : C51H58N8O7

  • Molecular Weight : 895.07

stdClass Object
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    [pname] => 3-(2-Aminoethyl)-2-(mesitylimino)-9,10-dimethoxy-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one
    [catalogue_number] => PA 05 2271016
    [category_ids] => ,82,78,70,
    [chemical_name] => 
    [weight] => 434.54
    [form] => C25H30N4O3
    [cas] => 298680-39-4
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PA 05 2271016

3-(2-Aminoethyl)-2-(mesitylimino)-9,10-dimethoxy-2,3,6,7-tetrahydro-4H-pyrimido[6,1-a]isoquinolin-4-one


  • Catalogue No.:PA 05 2271016

  • CAS :

    298680-39-4

  • Molecular Formula : C25H30N4O3

  • Molecular Weight : 434.54

stdClass Object
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    [pname] => 2-(2-(2-(Mesitylimino)-9,10-dimethoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)isoindoline-1,3-dione
    [catalogue_number] => PA 05 2271017
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    [weight] => 564.64
    [form] => C33H32N4O5
    [cas] => 298680-38-3
    [pslug] => 298680-38-3-2-2-2-mesitylimino-9-10-dimethoxy-4-oxo-6-7-dihydro-2h-pyrimido-6-1-a-isoquinolin-3-4h-yl-ethyl-isoindoline-1-3-dione-pa052271017
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PA 05 2271017

2-(2-(2-(Mesitylimino)-9,10-dimethoxy-4-oxo-6,7-dihydro-2H-pyrimido[6,1-a]isoquinolin-3(4H)-yl)ethyl)isoindoline-1,3-dione


  • Catalogue No.:PA 05 2271017

  • CAS :

    298680-38-3

  • Molecular Formula : C33H32N4O5

  • Molecular Weight : 564.64