efinaconazole
Pharmaceutical standards
- Efinaconazole acts as a 14α-demethylase inhibitor. which indicated in the treatment of fungal infection of the nail, known as onychomycosis.. Reference standards of Efinaconazole API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below
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[catalogue_number] => PA 05 79000
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Catalogue No.:PA 05 79000
Molecular Formula : C18H22F2N4O
Molecular Weight : 348.39
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Catalogue No.:PA 05 79510
Molecular Formula : C18H22F2N4O
Molecular Weight : 348.39
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(2R,3R)-2-(2,4-difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 79520
Molecular Formula : C12H13F2N3O2
Molecular Weight : 269.25
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(2S,3S)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 79530
Molecular Formula : C12H13F2N3O2
Molecular Weight : 269.25
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(2R,3S)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 79540
Molecular Formula : C12H13F2N3O2
Molecular Weight : 269.25
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(2S,3R)-2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 79550
Molecular Formula : C12H13F2N3O2
Molecular Weight : 269.25
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Catalogue No.:PA 05 79560
Molecular Formula : C18H22F2N4O
Molecular Weight : 348.39
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Catalogue No.:PA 05 79570
Molecular Formula : C18H22F2N4O
Molecular Weight : 348.39
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(2R,3R)-2-(2,4-Difluorophenyl)-1-(4H-1,2,4-triazol-4-yl)butane-2,3-diol
Catalogue No.:PA 05 79740
Molecular Formula : C12H13F2N3O2
Molecular Weight : 269.25
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Efinaconazole(2R,3R)Regiamer
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(2R,3R)-2-(2-Fluoro-4-(4-methylenepiperidin-1-yl)phenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Catalogue No.:PA 05 79760
Molecular Formula : C24H32FN5O
Molecular Weight : 425.55
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(2R,3R)-3-((1H-1,2,4-Triazol-1-yl)methyl)-6-fluoro-3-hydroxy-2-methyl-4'-methylenespiro[indoline-1,1'-piperidin]-1-ium Fluoride
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(2R,3R)-3-(2,4-Difluorophenyl)-3,4-epoxybutan-2-ol
Catalogue No.:PA 05 79780
Molecular Formula : C10H10F2O2
Molecular Weight : 200.18
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(S,E)-3-(2,4-Difluorophenyl)-4-(1H-1,2,4-triazol-1-yl)but-3-en-2-ol
Catalogue No.:PA 05 79790
Molecular Formula : C12H11F2N3O
Molecular Weight : 251.24
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(2S)-1-(2,4-Difluorophenyl)-2-((tetrahydro-2H-pyran-2-yl)oxy)propan-1-one
Catalogue No.:PA 05 79800
Molecular Formula : C14H16F2O3
Molecular Weight : 270.28
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(2R,3R)-2-(2,4-Difluorophenyl)-3-(3-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
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2-((1-((S)-2-(2,4-Difluorophenyl)oxiran-2-yl)vinyl)oxy)tetrahydro-2H-pyran
Catalogue No.:PA 05 79820
Molecular Formula : C15H16F2O3
Molecular Weight : 282.29
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Des-4-methylenepiperidine Efinaconazole
Catalogue No.:PA 05 0791000
Molecular Formula : C12H13F2N3O2
Molecular Weight : 269.25
stdClass Object
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(2S,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile
Catalogue No.:PA 05 0791001
Molecular Formula : C13H12F2N4O
Molecular Weight : 278.26
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[weight] => 296.28
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(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanamide
Catalogue No.:PA 05 0791002
Molecular Formula : C13H14F2N4O2
Molecular Weight : 296.28
stdClass Object
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[pname] => 1-(((2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
[catalogue_number] => PA 05 0791003
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[chemical_name] =>
[weight] => 251.24
[form] => C12H11F2N3O
[cas] => 127000-90-2
[pslug] => 127000-90-2-1-2r-3s-2-2-4-difluorophenyl-3-methyloxiran-2-yl-methyl-1h-1-2-4-triazole-pa050791003
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1-(((2R,3S)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
Catalogue No.:PA 05 0791003
Molecular Formula : C12H11F2N3O
Molecular Weight : 251.24
stdClass Object
(
[pname] => Efinaconazole 4-Desfluoro Impurity
[catalogue_number] => PA 05 0791004
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[chemical_name] =>
[weight] => 330.41
[form] => C18H23FN4O
[cas] => NA
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Efinaconazole 4-Desfluoro Impurity
Catalogue No.:PA 05 0791004
Molecular Formula : C18H23FN4O
Molecular Weight : 330.41
stdClass Object
(
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[chemical_name] =>
[weight] => 233.27
[form] => C12H15N3O2
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(2R,3R)-2-Phenyl-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 0791005
Molecular Formula : C12H15N3O2
Molecular Weight : 233.27
stdClass Object
(
[pname] => (2S,3S)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile
[catalogue_number] => PA 05 0791006
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[weight] => 278.26
[form] => C13H12F2N4O
[cas] => 2001051-99-4
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(2S,3S)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile
Catalogue No.:PA 05 0791006
Molecular Formula : C13H12F2N4O
Molecular Weight : 278.26
stdClass Object
(
[pname] => (2R,3R)-2-(4-Fluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
[catalogue_number] => PA 05 0791007
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[chemical_name] =>
[weight] => 330.41
[form] => C18H23FN4O
[cas] => 2055038-64-5
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(2R,3R)-2-(4-Fluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Catalogue No.:PA 05 0791007
Molecular Formula : C18H23FN4O
Molecular Weight : 330.41
stdClass Object
(
[pname] => Efinaconazole-N-oxide
[catalogue_number] => PA 05 0791008
[category_ids] => ,69,78,70,82,
[chemical_name] =>
[weight] => 364.4
[form] => C18H22F2N4O2
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stdClass Object
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[pname] => (R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one
[catalogue_number] => PA 05 0791009
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[chemical_name] =>
[weight] => 186.16
[form] => C9H8F2O2
[cas] => 126918-16-9
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(R)-1-(2,4-Difluorophenyl)-2-hydroxypropan-1-one
Catalogue No.:PA 05 0791009
Molecular Formula : C9H8F2O2
Molecular Weight : 186.16
stdClass Object
(
[pname] => 1-(4-Bromo-3-fluorophenyl)-1H-1,2,4-triazole
[catalogue_number] => PA 05 0791010
[category_ids] => ,78,70,82,
[chemical_name] =>
[weight] => 242.05
[form] => C8H5BrFN3
[cas] => 1783748-37-7
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1-(4-Bromo-3-fluorophenyl)-1H-1,2,4-triazole
Catalogue No.:PA 05 0791010
Molecular Formula : C8H5BrFN3
Molecular Weight : 242.05
stdClass Object
(
[pname] => 1-(2-Bromo-5-fluorophenyl)-1H-1,2,4-triazole
[catalogue_number] => PA 05 0791011
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[chemical_name] =>
[weight] => 242.05
[form] => C8H5BrFN3
[cas] => 909274-76-6
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1-(2-Bromo-5-fluorophenyl)-1H-1,2,4-triazole
Catalogue No.:PA 05 0791011
Molecular Formula : C8H5BrFN3
Molecular Weight : 242.05
stdClass Object
(
[pname] => 2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
[catalogue_number] => PA 05 0791012
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[chemical_name] =>
[weight] => 269.25
[form] => C12H13F2N3O2
[cas] => 161346-23-2
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2-(2,4-Difluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 0791012
Molecular Formula : C12H13F2N3O2
Molecular Weight : 269.25
stdClass Object
(
[pname] => (2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
[catalogue_number] => PA 05 0791013
[category_ids] => ,80,69,78,70,82,
[chemical_name] =>
[weight] => 347.34
[form] => C13H15F2N3O4S
[cas] => 133775-26-5
[pslug] => 133775-26-5-2r-3r-3-2-4-difluorophenyl-3-hydroxy-4-1h-1-2-4-triazol-1-yl-butan-2-yl-methanesulfonate-pa050791013
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(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl methanesulfonate
Catalogue No.:PA 05 0791013
Molecular Formula : C13H15F2N3O4S
Molecular Weight : 347.34
stdClass Object
(
[pname] => (2R,3R)-2-(2,4-Difluorophenyl)-3-(4-(hydroxymethyl)piperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
[catalogue_number] => PA 05 0791014
[category_ids] => ,80,69,78,82,
[chemical_name] =>
[weight] => 366.41
[form] => C18H24F2N4O2
[cas] => NA
[pslug] => 2r-3r-2-2-4-difluorophenyl-3-4-hydroxymethyl-piperidin-1-yl-1-1h-1-2-4-triazol-1-yl-butan-2-ol-pa050791014
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(2R,3R)-2-(2,4-Difluorophenyl)-3-(4-(hydroxymethyl)piperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Catalogue No.:PA 05 0791014
Molecular Formula : C18H24F2N4O2
Molecular Weight : 366.41
stdClass Object
(
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[catalogue_number] => PA 05 0791015
[category_ids] => ,80,69,78,82,
[chemical_name] =>
[weight] => 251.26
[form] => C12H14FN3O2
[cas] => 150803-08-0
[pslug] => 150803-08-0-2r-3r-2-4-fluorophenyl-1-1h-1-2-4-triazol-1-yl-butane-2-3-diol-pa050791015
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(2R,3R)-2-(4-Fluorophenyl)-1-(1H-1,2,4-triazol-1-yl)butane-2,3-diol
Catalogue No.:PA 05 0791015
Molecular Formula : C12H14FN3O2
Molecular Weight : 251.26
stdClass Object
(
[pname] => (2R,3R)-2-(2,4-Difluorophenyl)-3-(1-oxa-6-azaspiro[2.5]octan-6-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
[catalogue_number] => PA 05 0791016
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[chemical_name] =>
[weight] => 364.4
[form] => C18H22F2N4O2
[cas] => NA
[pslug] => 2r-3r-2-2-4-difluorophenyl-3-1-oxa-6-azaspiro-2-5-octan-6-yl-1-1h-1-2-4-triazol-1-yl-butan-2-ol-pa050791016
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(2R,3R)-2-(2,4-Difluorophenyl)-3-(1-oxa-6-azaspiro[2.5]octan-6-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
stdClass Object
(
[pname] => (R)-2-Hydroxy-1-morpholinopropan-1-one
[catalogue_number] => PA 05 0791017
[category_ids] => ,80,69,78,70,82,
[chemical_name] =>
[weight] => 159.19
[form] => C7H13NO3
[cas] => 135206-87-0
[pslug] => 135206-87-0-r-2-hydroxy-1-morpholinopropan-1-one-pa050791017
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(R)-2-Hydroxy-1-morpholinopropan-1-one
Catalogue No.:PA 05 0791017
Molecular Formula : C7H13NO3
Molecular Weight : 159.19
stdClass Object
(
[pname] => Mixture of (2R,3S) & (2S,3R) Efinaconazole
[catalogue_number] => PA 05 0791018
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[chemical_name] =>
[weight] => 348.4
[form] => C18H22F2N4O
[cas] => 188904-85-0
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Mixture of (2R,3S) & (2S,3R) Efinaconazole
stdClass Object
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[pname] => (2R,3R)-3-(4-Methylenepiperidin-1-yl)-2-phenyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
[catalogue_number] => PA 05 0791019
[category_ids] => ,80,69,78,70,82,
[chemical_name] =>
[weight] => 312.42
[form] => C18H24N4O
[cas] => 2055038-65-6
[pslug] => 2055038-65-6-2r-3r-3-4-methylenepiperidin-1-yl-2-phenyl-1-1h-1-2-4-triazol-1-yl-butan-2-ol-pa050791019
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(2R,3R)-3-(4-Methylenepiperidin-1-yl)-2-phenyl-1-(1H-1,2,4-triazol-1-yl)butan-2-ol
Catalogue No.:PA 05 0791019
Molecular Formula : C18H24N4O
Molecular Weight : 312.42
