Edoxaban-impurities | Pharmaffiliates

edoxaban

Edoxaban is a member of the Novel Oral Anti-Coagulants class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor.. Reference standards of Edoxaban API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => tert-Butyl ((1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)carbamate
    [catalogue_number] => PA 05 0821085
    [category_ids] => ,69,71,78,70,
    [chemical_name] => 
    [weight] => 285.39
    [form] => C14H27N3O3
    [cas] => 2408468-95-9
    [pslug] => 2408468-95-9-tert-butyl-1s-2r-4s-2-amino-4-dimethylcarbamoyl-cyclohexyl-carbamate-pa050821085
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PA 05 0821085

tert-Butyl ((1S,2R,4S)-2-amino-4-(dimethylcarbamoyl)cyclohexyl)carbamate


  • Catalogue No.:PA 05 0821085

  • CAS :

    2408468-95-9

  • Molecular Formula : C14H27N3O3

  • Molecular Weight : 285.39

stdClass Object
(
    [pname] => Ethyl 2-((4,5-dichloropyridin-2-yl)amino)-2-oxoacetate
    [catalogue_number] => PA 05 0821086
    [category_ids] => ,79,80,69,71,78,70,82,
    [chemical_name] => 
    [weight] => 263.07
    [form] => C9H8Cl2N2O3
    [cas] => 2250242-53-4
    [pslug] => 2250242-53-4-ethyl-2-4-5-dichloropyridin-2-yl-amino-2-oxoacetate-pa050821086
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PA 05 0821086

Ethyl 2-((4,5-dichloropyridin-2-yl)amino)-2-oxoacetate


  • Catalogue No.:PA 05 0821086

  • CAS :

    2250242-53-4

  • Molecular Formula : C9H8Cl2N2O3

  • Molecular Weight : 263.07

stdClass Object
(
    [pname] => N,N'-((1S,2R,4S)-4-(Dimethylcarbamoyl)cyclohexane-1,2-diyl)bis(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide)
    [catalogue_number] => PA 05 0821087
    [category_ids] => ,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 545.72
    [form] => C25H35N7O3S2
    [cas] => 2803419-53-4
    [pslug] => 2803419-53-4-n-n-1s-2r-4s-4-dimethylcarbamoyl-cyclohexane-1-2-diyl-bis-5-methyl-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-2-carboxamide-pa050821087
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PA 05 0821087

N,N'-((1S,2R,4S)-4-(Dimethylcarbamoyl)cyclohexane-1,2-diyl)bis(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide)


  • Catalogue No.:PA 05 0821087

  • CAS :

    2803419-53-4

  • Molecular Formula : C25H35N7O3S2

  • Molecular Weight : 545.72

stdClass Object
(
    [pname] => Ethyl 2-oxo-2-(pyridin-2-ylamino)acetate Hydrochloride
    [catalogue_number] => PA 05 0821088
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 230.65
    [form] => C9H11ClN2O3
    [cas] => NA
    [pslug] => ethyl-2-oxo-2-pyridin-2-ylamino-acetate-hydrochloride-pa050821088
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PA 05 0821088

Ethyl 2-oxo-2-(pyridin-2-ylamino)acetate Hydrochloride


  • Catalogue No.:PA 05 0821088

  • CAS :

    NA

  • Molecular Formula : C9H11ClN2O3

  • Molecular Weight : 230.65

stdClass Object
(
    [pname] => N1-(5-Bromopyridin-2-yl)-N2-((1R,2S,4R)-4-(dimethylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
    [catalogue_number] => PA 05 0821089
    [category_ids] => ,79,80,69,71,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 607.48
    [form] => C23H27BrN8O5S
    [cas] => NA
    [pslug] => n1-5-bromopyridin-2-yl-n2-1r-2s-4r-4-dimethylcarbamoyl-2-5-nitroso-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-2-carboxamido-cyclohexyl-oxalamide-pa050821089
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PA 05 0821089

N1-(5-Bromopyridin-2-yl)-N2-((1R,2S,4R)-4-(dimethylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide


  • Catalogue No.:PA 05 0821089

  • CAS :

    NA

  • Molecular Formula : C23H27BrN8O5S

  • Molecular Weight : 607.48

stdClass Object
(
    [pname] => Methyl (1S,3R,4S)-4-(2-((5-chloropyridin-2-yl)amino)-2-oxoacetamido)-3-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylate
    [catalogue_number] => PA 05 0821090
    [category_ids] => ,79,80,69,71,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 549.99
    [form] => C22H24ClN7O6S
    [cas] => NA
    [pslug] => methyl-1s-3r-4s-4-2-5-chloropyridin-2-yl-amino-2-oxoacetamido-3-5-nitroso-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-2-carboxamido-cyclohexane-1-carboxylate-pa050821090
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PA 05 0821090

Methyl (1S,3R,4S)-4-(2-((5-chloropyridin-2-yl)amino)-2-oxoacetamido)-3-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexane-1-carboxylate


  • Catalogue No.:PA 05 0821090

  • CAS :

    NA

  • Molecular Formula : C22H24ClN7O6S

  • Molecular Weight : 549.99

stdClass Object
(
    [pname] => N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(methylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
    [catalogue_number] => PA 05 0821091
    [category_ids] => ,79,80,69,71,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 549
    [form] => C22H25ClN8O5S
    [cas] => NA
    [pslug] => n1-5-chloropyridin-2-yl-n2-1s-2r-4s-4-methylcarbamoyl-2-5-nitroso-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-2-carboxamido-cyclohexyl-oxalamide-pa050821091
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PA 05 0821091

N1-(5-Chloropyridin-2-yl)-N2-((1S,2R,4S)-4-(methylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide


  • Catalogue No.:PA 05 0821091

  • CAS :

    NA

  • Molecular Formula : C22H25ClN8O5S

  • Molecular Weight : 549

stdClass Object
(
    [pname] => 2-(((1S,2R,4S)-4-(Dimethylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic Acid
    [catalogue_number] => PA 05 0821092
    [category_ids] => ,79,80,69,71,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 452.49
    [form] => C18H24N6O6S
    [cas] => NA
    [pslug] => 2-1s-2r-4s-4-dimethylcarbamoyl-2-5-nitroso-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-2-carboxamido-cyclohexyl-amino-2-oxoacetic-acid-pa050821092
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PA 05 0821092

2-(((1S,2R,4S)-4-(Dimethylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)amino)-2-oxoacetic Acid


  • Catalogue No.:PA 05 0821092

  • CAS :

    NA

  • Molecular Formula : C18H24N6O6S

  • Molecular Weight : 452.49

stdClass Object
(
    [pname] => N1-(5-Chloropyridin-2-yl)-N2-((1S,2S,4R)-4-(dimethylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
    [catalogue_number] => PA 05 0821093
    [category_ids] => ,79,80,69,71,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 563.03
    [form] => C23H27ClN8O5S
    [cas] => NA
    [pslug] => n1-5-chloropyridin-2-yl-n2-1s-2s-4r-4-dimethylcarbamoyl-2-5-nitroso-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-2-carboxamido-cyclohexyl-oxalamide-pa050821093
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PA 05 0821093

N1-(5-Chloropyridin-2-yl)-N2-((1S,2S,4R)-4-(dimethylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide


  • Catalogue No.:PA 05 0821093

  • CAS :

    NA

  • Molecular Formula : C23H27ClN8O5S

  • Molecular Weight : 563.03

stdClass Object
(
    [pname] => N1-(5-Chloropyridin-2-yl)-N2-((1R,2S,4R)-4-(dimethylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide
    [catalogue_number] => PA 05 0821094
    [category_ids] => ,79,80,69,71,78,70,82,88,162,
    [chemical_name] => 
    [weight] => 563.03
    [form] => C23H27ClN8O5S
    [cas] => NA
    [pslug] => n1-5-chloropyridin-2-yl-n2-1r-2s-4r-4-dimethylcarbamoyl-2-5-nitroso-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-2-carboxamido-cyclohexyl-oxalamide-pa050821094
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PA 05 0821094

N1-(5-Chloropyridin-2-yl)-N2-((1R,2S,4R)-4-(dimethylcarbamoyl)-2-(5-nitroso-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)oxalamide


  • Catalogue No.:PA 05 0821094

  • CAS :

    NA

  • Molecular Formula : C23H27ClN8O5S

  • Molecular Weight : 563.03

stdClass Object
(
    [pname] => tert-Butyl ((1R,2S,5S)-5-(dimethylcarbamoyl)-2-(2-oxo-2-(pyridin-2-ylamino)acetamido)cyclohexyl)carbamate
    [catalogue_number] => PA 05 0821095
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 433.51
    [form] => C21H31N5O5
    [cas] => NA
    [pslug] => tert-butyl-1r-2s-5s-5-dimethylcarbamoyl-2-2-oxo-2-pyridin-2-ylamino-acetamido-cyclohexyl-carbamate-pa050821095
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PA 05 0821095

tert-Butyl ((1R,2S,5S)-5-(dimethylcarbamoyl)-2-(2-oxo-2-(pyridin-2-ylamino)acetamido)cyclohexyl)carbamate


  • Catalogue No.:PA 05 0821095

  • CAS :

    NA

  • Molecular Formula : C21H31N5O5

  • Molecular Weight : 433.51

stdClass Object
(
    [pname] => N1-((1S,2R,4S)-2-Acetamido-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide
    [catalogue_number] => PA 05 0821096
    [category_ids] => ,79,80,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 409.87
    [form] => C18H24ClN5O4
    [cas] => NA
    [pslug] => n1-1s-2r-4s-2-acetamido-4-dimethylcarbamoyl-cyclohexyl-n2-5-chloropyridin-2-yl-oxalamide-pa050821096
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PA 05 0821096

N1-((1S,2R,4S)-2-Acetamido-4-(dimethylcarbamoyl)cyclohexyl)-N2-(5-chloropyridin-2-yl)oxalamide


  • Catalogue No.:PA 05 0821096

  • CAS :

    NA

  • Molecular Formula : C18H24ClN5O4

  • Molecular Weight : 409.87

stdClass Object
(
    [pname] => rel-Ethyl (1R,3S,4S)-4-amino-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate
    [catalogue_number] => PA 05 0821097
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 286.37
    [form] => C14H26N2O4
    [cas] => 1356337-01-3
    [pslug] => 1356337-01-3-rel-ethyl-1r-3s-4s-4-amino-3-tert-butoxycarbonyl-amino-cyclohexane-1-carboxylate-pa050821097
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PA 05 0821097

rel-Ethyl (1R,3S,4S)-4-amino-3-((tert-butoxycarbonyl)amino)cyclohexane-1-carboxylate


  • Catalogue No.:PA 05 0821097

  • CAS :

    1356337-01-3

  • Molecular Formula : C14H26N2O4

  • Molecular Weight : 286.37

stdClass Object
(
    [pname] => Ent-Edoxaban Tosylate
    [catalogue_number] => PA 05 0821098
    [category_ids] => ,88,82,80,79,78,71,70,69,
    [chemical_name] => 
    [weight] => 720.26
    [form] =>  C31H38ClN7O7S2
    [cas] => 2605225-75-8
    [pslug] => 2605225-75-8-ent-edoxaban-tosylate-pa050821098
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PA 05 0821098

Ent-Edoxaban Tosylate


  • Catalogue No.:PA 05 0821098

  • CAS :

    2605225-75-8

  • Molecular Formula : C31H38ClN7O7S2

  • Molecular Weight : 720.26

stdClass Object
(
    [pname] => Edoxaban (RRR)-Isomer Tosylate Salt
    [catalogue_number] => PA 05 0821099
    [category_ids] => ,79,80,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 720.26
    [form] => C31H38ClN7O7S2
    [cas] => 2852734-46-2
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PA 05 0821099

Edoxaban (RRR)-Isomer Tosylate Salt


  • Catalogue No.:PA 05 0821099

  • CAS :

    2852734-46-2

  • Molecular Formula : C31H38ClN7O7S2

  • Molecular Weight : 720.26

stdClass Object
(
    [pname] => Edoxaban (SSS)-Isomer Tosylate Salt
    [catalogue_number] => PA 05 0821100
    [category_ids] => ,79,80,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 720.26
    [form] => C31H38ClN7O7S2
    [cas] => 2852734-44-0
    [pslug] => 2852734-44-0-edoxaban-sss-isomer-tosylate-salt-pa050821100
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PA 05 0821100

Edoxaban (SSS)-Isomer Tosylate Salt


  • Catalogue No.:PA 05 0821100

  • CAS :

    2852734-44-0

  • Molecular Formula : C31H38ClN7O7S2

  • Molecular Weight : 720.26

stdClass Object
(
    [pname] => Benzyl ((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)carbamate
    [catalogue_number] => PA 05 0821101
    [category_ids] => ,79,80,69,71,78,70,82,88,
    [chemical_name] => 
    [weight] => 499.63
    [form] => C25H33N5O4S
    [cas] => 2759920-22-2
    [pslug] => 2759920-22-2-benzyl-1s-2r-4s-4-dimethylcarbamoyl-2-5-methyl-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-2-carboxamido-cyclohexyl-carbamate-pa050821101
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PA 05 0821101

Benzyl ((1S,2R,4S)-4-(dimethylcarbamoyl)-2-(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamido)cyclohexyl)carbamate


  • Catalogue No.:PA 05 0821101

  • CAS :

    2759920-22-2

  • Molecular Formula : C25H33N5O4S

  • Molecular Weight : 499.63

stdClass Object
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    [pname] => 2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine
    [catalogue_number] => PA 05 0821102
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 233.13
    [form] => C7H9BrN2S
    [cas] => 143150-92-9
    [pslug] => 143150-92-9-2-bromo-5-methyl-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-pa050821102
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PA 05 0821102

2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine


  • Catalogue No.:PA 05 0821102

  • CAS :

    143150-92-9

  • Molecular Formula : C7H9BrN2S

  • Molecular Weight : 233.13

stdClass Object
(
    [pname] => 2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine Tosylate
    [catalogue_number] => PA 05 0821103
    [category_ids] => ,71,78,70,82,
    [chemical_name] => 
    [weight] => 405.33
    [form] => C14H17BrN2O3S2
    [cas] => 852291-42-0
    [pslug] => 852291-42-0-2-bromo-5-methyl-4-5-6-7-tetrahydrothiazolo-5-4-c-pyridine-tosylate-pa050821103
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PA 05 0821103

2-Bromo-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine Tosylate


  • Catalogue No.:PA 05 0821103

  • CAS :

    852291-42-0

  • Molecular Formula : C14H17BrN2O3S2

  • Molecular Weight : 405.33