Dacomitinib (trade name Vizimpro) is a drug candidate under development by Pfizer for the treatment of non-small-cell lung carcinoma (NSCLC). It is a selective and irreversible inhibitor of EGFR. Reference standards of Dacomitinib API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
stdClass Object ( [pname] => Dacomitinib - API Standards [catalogue_number] => PA 04 2190000 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 469.95 [form] => C24H25ClFN5O2 [cas] => 1110813-31-4 [pslug] => 1110813-31-4-dacomitinib-api-pa042190000 [latest_product] => 0 [linkproducts] => 1 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 2190000
CAS :
Molecular Formula : C24H25ClFN5O2
Molecular Weight : 469.95
stdClass Object ( [pname] => 1-(4-((3-Chloro-4-fluorocyclohexyl)amino)-7-methoxyquinazolin-6-yl)-5-hydroxypyrrolidin-2-one [catalogue_number] => PA 04 2191000 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 402.81 [form] => C19H16ClFN4O3 [cas] => 2190490-31-2 [pslug] => 2190490-31-2-1-4-3-chloro-4-fluorocyclohexyl-amino-7-methoxyquinazolin-6-yl-5-hydroxypyrrolidin-2-one-pa042191000 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 2191000
Molecular Formula : C19H16ClFN4O3
Molecular Weight : 402.81
stdClass Object ( [pname] => Dacomitinib Desmethyl Impurity [catalogue_number] => PA 04 2191001 [category_ids] => ,75,76,78,70,82, [chemical_name] => [weight] => 455.92 [form] => C23H23ClFN5O2 [cas] => 2468202-15-3 [pslug] => 2468202-15-3-dacomitinib-desmethyl-impurity-pa042191001 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 2191001
Molecular Formula : C23H23ClFN5O2
Molecular Weight : 455.92
stdClass Object ( [pname] => Dacomitinib Z-Isomer [catalogue_number] => PA 04 2191002 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 469.95 [form] => C24H25ClFN5O2 [cas] => NA [pslug] => dacomitinib-z-isomer-pa042191002 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 2191002
stdClass Object ( [pname] => (E)-N-(4-((3-Chloro-4-fluorophenyl)(nitroso)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)but-2-enamide [catalogue_number] => PA 04 2191003 [category_ids] => ,78,75,70,76,82,162, [chemical_name] => [weight] => 498.94 [form] => C24H24ClFN6O3 [cas] => NA [pslug] => e-n-4-3-chloro-4-fluorophenyl-nitroso-amino-7-methoxyquinazolin-6-yl-4-piperidin-1-yl-but-2-enamide-pa042191003 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 2191003
Molecular Formula : C24H24ClFN6O3
Molecular Weight : 498.94
stdClass Object ( [pname] => 3-((3-Chloro-4-fluorophenyl)amino)-N-(4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-4-(piperidin-1-yl)butanamide [catalogue_number] => PA 04 2191004 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 615.51 [form] => C30H30Cl2F2N6O2 [cas] => NA [pslug] => 3-3-chloro-4-fluorophenyl-amino-n-4-3-chloro-4-fluorophenyl-amino-7-methoxyquinazolin-6-yl-4-piperidin-1-yl-butanamide-pa042191004 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 2191004
Molecular Formula : C30H30Cl2F2N6O2
Molecular Weight : 615.51
stdClass Object ( [pname] => N-(4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)-3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)amino)-4-(piperidin-1-yl)butanamide [catalogue_number] => PA 04 2191005 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 788.68 [form] => C39H37Cl2F2N9O3 [cas] => NA [pslug] => n-4-3-chloro-4-fluorophenyl-amino-7-methoxyquinazolin-6-yl-3-4-3-chloro-4-fluorophenyl-amino-7-methoxyquinazolin-6-yl-amino-4-piperidin-1-yl-butanamide-pa042191005 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 2191005
Molecular Formula : C39H37Cl2F2N9O3
Molecular Weight : 788.68
stdClass Object ( [pname] => N4-(3-Chloro-4-fluorophenyl)-7-methoxyquinazoline-4,6-diamine [catalogue_number] => PA 04 2191006 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 318.74 [form] => C15H12ClFN4O [cas] => 179552-75-1 [pslug] => 179552-75-1-n4-3-chloro-4-fluorophenyl-7-methoxyquinazoline-4-6-diamine-pa042191006 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 2191006
Molecular Formula : C15H12ClFN4O
Molecular Weight : 318.74
stdClass Object ( [pname] => (2E)-4-(1-Piperidinyl)-2-butenoic Acid Hydrochloride [catalogue_number] => PA 04 2191007 [category_ids] => ,78,75,70,76,82, [chemical_name] => [weight] => 205.68 [form] => C9H16ClNO2 [cas] => 197892-69-6 [pslug] => 197892-69-6-2e-4-1-piperidinyl-2-butenoic-acid-hydrochloride-pa042191007 [latest_product] => 0 [linkproducts] => 0 [offers_id] => [offers_name] => [offers_status] => [offers_start_date] => [offers_end_date] => [pageview] => [offers_slug] => [offers_product_id] => [offers_product_code] => [offers_master_id] => [offer_percentage] => [offers_product_main_cat] => )
Catalogue No.:PA 04 2191007
Molecular Formula : C9H16ClNO2
Molecular Weight : 205.68
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