Clozapine-impurities | Pharmaffiliates

clozapine

Clozapine is an atypical antipsychotic drug primarily used in people who are unresponsive to or intolerant to other antipsychotics.. Reference standards of Clozapine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below

stdClass Object
(
    [pname] => Clozapine - API Standards 
    [catalogue_number] => PA 03 72000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 326.83
    [form] => C18H19ClN4
    [cas] => 5786-21-0
    [pslug] => 5786-21-0-clozapine-api-pa0372000
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PA 03 72000

Clozapine - API Standards


  • Catalogue No.:PA 03 72000

  • CAS :

    5786-21-0

  • Molecular Formula : C18H19ClN4

  • Molecular Weight : 326.83

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stdClass Object
(
    [pname] => Clozapine - Impurity A
    [catalogue_number] => PA 03 72010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 244.68
    [form] => C13H9ClN2O
    [cas] => 50892-62-1
    [pslug] => 50892-62-1-clozapine-impurity-a-pa0372010
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PA 03 72010

Clozapine - Impurity A


  • Catalogue No.:PA 03 72010

  • CAS :

    50892-62-1

  • Molecular Formula : C13H9ClN2O

  • Molecular Weight : 244.68

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stdClass Object
(
    [pname] => Clozapine - Impurity B
    [catalogue_number] => PA 03 72020
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 539.46
    [form] => C30H24Cl2N6
    [cas] => 263366-81-0
    [pslug] => 263366-81-0-clozapine-impurity-b-pa0372020
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    [offers_product_code] => PA 03 72020
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PA 03 72020

Clozapine - Impurity B


  • Catalogue No.:PA 03 72020

  • CAS :

    263366-81-0

  • Molecular Formula : C30H24Cl2N6

  • Molecular Weight : 539.46

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stdClass Object
(
    [pname] => Clozapine - Impurity C (Freebase)
    [catalogue_number] => PA 03 72030
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 312.8
    [form] => C17H17ClN4
    [cas] => 6104-71-8
    [pslug] => 6104-71-8-clozapine-impurity-c-freebase-pa0372030
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    [offers_product_code] => PA 03 72030
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PA 03 72030

Clozapine - Impurity C (Freebase)


  • Catalogue No.:PA 03 72030

  • CAS :

    6104-71-8

  • Molecular Formula : C17H17ClN4

  • Molecular Weight : 312.8

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stdClass Object
(
    [pname] => Clozapine - Impurity D (Freebase)
    [catalogue_number] => PA 03 72040
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 344.84
    [form] => C18H21ClN4O
    [cas] => 65514-71-8
    [pslug] => 65514-71-8-clozapine-impurity-d-freebase-pa0372040
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    [offers_product_code] => PA 03 72040
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PA 03 72040

Clozapine - Impurity D (Freebase)


  • Catalogue No.:PA 03 72040

  • CAS :

    65514-71-8

  • Molecular Formula : C18H21ClN4O

  • Molecular Weight : 344.84

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stdClass Object
(
    [pname] => Clozapine N-Oxide
    [catalogue_number] => PA 03 72550
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 342.83
    [form] => C18H19ClN4O
    [cas] => 34233-69-7
    [pslug] => 34233-69-7-clozapine-n-oxide-pa0372550
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    [offers_product_code] => PA 03 72550
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PA 03 72550

Clozapine N-Oxide


  • Catalogue No.:PA 03 72550

  • CAS :

    34233-69-7

  • Molecular Formula : C18H19ClN4O

  • Molecular Weight : 342.83

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stdClass Object
(
    [pname] => 2-((2-Amino-4-chlorophenyl)amino)benzoic Acid
    [catalogue_number] => PA 03 72570
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 262.69
    [form] => C13H11ClN2O2
    [cas] => 67990-66-3
    [pslug] => 67990-66-3-2-2-amino-4-chlorophenyl-amino-benzoic-acid-pa0372570
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PA 03 72570

2-((2-Amino-4-chlorophenyl)amino)benzoic Acid


  • Catalogue No.:PA 03 72570

  • CAS :

    67990-66-3

  • Molecular Formula : C13H11ClN2O2

  • Molecular Weight : 262.69

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stdClass Object
(
    [pname] => 4-(8-Chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-1-piperazinecarboxylic Acid-d8 1,1-Dimethylethyl Ester
    [catalogue_number] => PA STI 019920
    [category_ids] => ,78,70,82,98,
    [chemical_name] => 
    [weight] => 420.96
    [form] => C22H17D8ClN4O2
    [cas] => 2733718-84-6
    [pslug] => 2733718-84-6-4-8-chloro-5h-dibenzo-b-e-1-4-diazepin-11-yl-1-piperazinecarboxylic-acid-d8-1-1-dimethylethyl-ester-pasti019920
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PA STI 019920

4-(8-Chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)-1-piperazinecarboxylic Acid-d8 1,1-Dimethylethyl Ester


  • Catalogue No.:PA STI 019920

  • CAS :

    2733718-84-6

  • Molecular Formula : C22H17D8ClN4O2

  • Molecular Weight : 420.96

stdClass Object
(
    [pname] => Clozapine-d8
    [catalogue_number] => PA STI 022360
    [category_ids] => ,78,70,82,98,
    [chemical_name] => 
    [weight] => 334.87
    [form] => C18H11D8ClN4
    [cas] => 1185053-50-2
    [pslug] => 1185053-50-2-clozapine-d8-pasti022360
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PA STI 022360

Clozapine-d8


  • Catalogue No.:PA STI 022360

  • CAS :

    1185053-50-2

  • Molecular Formula : C18H11D8ClN4

  • Molecular Weight : 334.87

stdClass Object
(
    [pname] => Clozapine-d3
    [catalogue_number] => PA STI 022370
    [category_ids] => ,79,80,78,70,82,98,
    [chemical_name] => 
    [weight] => 329.84
    [form] => C18H16D3ClN4
    [cas] => 1215691-72-7
    [pslug] => 1215691-72-7-clozapine-d3-pasti022370
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PA STI 022370

Clozapine-d3


  • Catalogue No.:PA STI 022370

  • CAS :

    1215691-72-7

  • Molecular Formula : C18H16D3ClN4

  • Molecular Weight : 329.84

stdClass Object
(
    [pname] => 2-[(4-Chloro-2-nitrophenyl)amino]benzoic Acid
    [catalogue_number] => PA 03 72540
    [category_ids] => ,80,78,70,82,
    [chemical_name] => 
    [weight] => 292.68
    [form] => C13H9ClN2O4
    [cas] => 60091-87-4
    [pslug] => 60091-87-4-2-4-chloro-2-nitrophenyl-amino-benzoic-acid-pa0372540
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PA 03 72540

2-[(4-Chloro-2-nitrophenyl)amino]benzoic Acid


  • Catalogue No.:PA 03 72540

  • CAS :

    60091-87-4

  • Molecular Formula : C13H9ClN2O4

  • Molecular Weight : 292.68

stdClass Object
(
    [pname] => 11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
    [catalogue_number] => PA 03 72560
    [category_ids] => 82,78,70
    [chemical_name] => 
    [weight] => 292.39
    [form] => C18H20N4
    [cas] => 1977-07-7
    [pslug] => 1977-07-7-11-4-methylpiperazin-1-yl-5H-dibenzo-b-e-1-4-diazepine-pa0372560
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PA 03 72560

11-(4-Methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine


  • Catalogue No.:PA 03 72560

  • CAS :

    1977-07-7

  • Molecular Formula : C18H20N4

  • Molecular Weight : 292.39

stdClass Object
(
    [pname] => Clozapine Resolution Mixture
    [catalogue_number] => PA 03 0721000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
    [pslug] => clozapine-resolution-mixture-pa030721000
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PA 03 0721000

Clozapine Resolution Mixture


  • Catalogue No.:PA 03 0721000

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] => 2-((4-Chloro-2-nitrophenyl)amino)benzoyl chloride
    [catalogue_number] => PA 03 0721001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 311.12
    [form] => C13H8Cl2N2O3
    [cas] => 69414-55-7
    [pslug] => 69414-55-7-2-4-chloro-2-nitrophenyl-amino-benzoyl-chloride-pa030721001
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PA 03 0721001

2-((4-Chloro-2-nitrophenyl)amino)benzoyl chloride


  • Catalogue No.:PA 03 0721001

  • CAS :

    69414-55-7

  • Molecular Formula : C13H8Cl2N2O3

  • Molecular Weight : 311.12

stdClass Object
(
    [pname] => N-Acetyl clozapine
    [catalogue_number] => PA 03 0721002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 368.87
    [form] => C20H21ClN4O
    [cas] => 1025951-76-1
    [pslug] => 1025951-76-1-n-acetyl-clozapine-pa030721002
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PA 03 0721002

N-Acetyl clozapine


  • Catalogue No.:PA 03 0721002

  • CAS :

    1025951-76-1

  • Molecular Formula : C20H21ClN4O

  • Molecular Weight : 368.87

stdClass Object
(
    [pname] => 8-Chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine
    [catalogue_number] => PA 03 0721003
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 341.8
    [form] => C17H16ClN5O
    [cas] => NA
    [pslug] => 8-chloro-11-4-nitrosopiperazin-1-yl-5h-dibenzo-b-e-1-4-diazepine-pa030721003
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PA 03 0721003

8-Chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine


  • Catalogue No.:PA 03 0721003

  • CAS :

    NA

  • Molecular Formula : C17H16ClN5O

  • Molecular Weight : 341.8

stdClass Object
(
    [pname] => N-Nitroso Clozapine
    [catalogue_number] => PA 03 0721004
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 355.83
    [form] => C18H18ClN5O
    [cas] => 156632-03-0
    [pslug] => 156632-03-0-n-nitroso-clozapine-pa030721004
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PA 03 0721004

N-Nitroso Clozapine


  • Catalogue No.:PA 03 0721004

  • CAS :

    156632-03-0

  • Molecular Formula : C18H18ClN5O

  • Molecular Weight : 355.83

stdClass Object
(
    [pname] => 8-Chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 2,2,2-Trifluoroacetate
    [catalogue_number] => PA 03 0721005
    [category_ids] => ,70,75,78,82,162,
    [chemical_name] => 
    [weight] => 455.82
    [form] => C19H17ClF3N5O3
    [cas] => NA
    [pslug] => 8-chloro-11-4-nitrosopiperazin-1-yl-5h-dibenzo-b-e-1-4-diazepine-2-2-2-trifluoroacetate-pa030721005
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PA 03 0721005

8-Chloro-11-(4-nitrosopiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine 2,2,2-Trifluoroacetate


  • Catalogue No.:PA 03 0721005

  • CAS :

    NA

  • Molecular Formula : C19H17ClF3N5O3

  • Molecular Weight : 455.82

stdClass Object
(
    [pname] => (3aR,11aS)-5-(6-(4-Acryloylpiperazin-1-yl)pyridin-2-yl)-6-fluoro-10-methyl-1-(6-methyl-4-(trifluoromethyl)pyridin-2-yl)-1,3a,4,5,10,11a-hexahydro-2H-benzo[b]pyrrolo[2,3-f][1,4]diazocine-2,11(3H)-dione
    [catalogue_number] => PA 03 0721006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 637.64
    [form] => C32H31F4N7O3
    [cas] => 2924015-21-2
    [pslug] => 2924015-21-2-3ar-11as-5-6-4-acryloylpiperazin-1-yl-pyridin-2-yl-6-fluoro-10-methyl-1-6-methyl-4-trifluoromethyl-pyridin-2-yl-1-3a-4-5-10-11a-hexahydro-2h-benzo-b-pyrrolo-2-3-f-1-4-diazocine-2-11-3h-dione-pa030721006
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PA 03 0721006

(3aR,11aS)-5-(6-(4-Acryloylpiperazin-1-yl)pyridin-2-yl)-6-fluoro-10-methyl-1-(6-methyl-4-(trifluoromethyl)pyridin-2-yl)-1,3a,4,5,10,11a-hexahydro-2H-benzo[b]pyrrolo[2,3-f][1,4]diazocine-2,11(3H)-dione


  • Catalogue No.:PA 03 0721006

  • CAS :

    2924015-21-2

  • Molecular Formula : C32H31F4N7O3

  • Molecular Weight : 637.64

stdClass Object
(
    [pname] => (3aR,11aS)-5-((2-(4-Acryloylpiperazin-1-yl)oxazol-4-yl)methyl)-6-fluoro-10-methyl-1-(6-methyl-4-(trifluoromethyl)pyridin-2-yl)-1,3a,4,5,10,11a-hexahydro-2H-benzo[b]pyrrolo[2,3-f][1,4]diazocine-2,11(3H)-dione
    [catalogue_number] => PA 03 0721007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 641.63
    [form] => C31H31F4N7O4
    [cas] => 2924016-00-0
    [pslug] => 2924016-00-0-3ar-11as-5-2-4-acryloylpiperazin-1-yl-oxazol-4-yl-methyl-6-fluoro-10-methyl-1-6-methyl-4-trifluoromethyl-pyridin-2-yl-1-3a-4-5-10-11a-hexahydro-2h-benzo-b-pyrrolo-2-3-f-1-4-diazocine-2-11-3h-dione-pa030721007
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PA 03 0721007

(3aR,11aS)-5-((2-(4-Acryloylpiperazin-1-yl)oxazol-4-yl)methyl)-6-fluoro-10-methyl-1-(6-methyl-4-(trifluoromethyl)pyridin-2-yl)-1,3a,4,5,10,11a-hexahydro-2H-benzo[b]pyrrolo[2,3-f][1,4]diazocine-2,11(3H)-dione


  • Catalogue No.:PA 03 0721007

  • CAS :

    2924016-00-0

  • Molecular Formula : C31H31F4N7O4

  • Molecular Weight : 641.63

stdClass Object
(
    [pname] => 8-Chloro-5-nitroso-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one
    [catalogue_number] => PA 03 0721008
    [category_ids] => 162,82,78,76,75,70
    [chemical_name] => 
    [weight] => 273.68
    [form] => C13H8ClN3O2
    [cas] => 90353-66-5
    [pslug] => 90353-66-5-8-chloro-5-nitroso-5-10-dihydro-11h-dibenzo-b-e-1-4-diazepin-11-one-pa030721008
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PA 03 0721008

8-Chloro-5-nitroso-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one


  • Catalogue No.:PA 03 0721008

  • CAS :

    90353-66-5

  • Molecular Formula : C13H8ClN3O2

  • Molecular Weight : 273.68

stdClass Object
(
    [pname] => 8-Chloro-11-(4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazin-1-yl)-5-nitroso-5H-dibenzo[b,e][1,4]diazepine
    [catalogue_number] => PA 03 0721009
    [category_ids] => ,75,76,78,70,82,162,
    [chemical_name] => 
    [weight] => 568.46
    [form] => C30H23Cl2N7O
    [cas] => NA
    [pslug] => 8-chloro-11-4-8-chloro-5h-dibenzo-b-e-1-4-diazepin-11-yl-piperazin-1-yl-5-nitroso-5h-dibenzo-b-e-1-4-diazepine-pa030721009
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PA 03 0721009

8-Chloro-11-(4-(8-chloro-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazin-1-yl)-5-nitroso-5H-dibenzo[b,e][1,4]diazepine


  • Catalogue No.:PA 03 0721009

  • CAS :

    NA

  • Molecular Formula : C30H23Cl2N7O

  • Molecular Weight : 568.46

stdClass Object
(
    [pname] => N-(2-Amino-4-chlorophenyl)-N-(2-(4-methylpiperazine-1-carbonyl)phenyl)nitrous amide
    [catalogue_number] => PA 03 0721010
    [category_ids] => ,75,76,78,70,82,162,
    [chemical_name] => 
    [weight] => 373.84
    [form] => C18H20ClN5O2
    [cas] => NA
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PA 03 0721010

N-(2-Amino-4-chlorophenyl)-N-(2-(4-methylpiperazine-1-carbonyl)phenyl)nitrous amide


  • Catalogue No.:PA 03 0721010

  • CAS :

    NA

  • Molecular Formula : C18H20ClN5O2

  • Molecular Weight : 373.84

stdClass Object
(
    [pname] => 1,4-bis(8-Chloro-5-nitroso-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazine
    [catalogue_number] => PA 03 0721011
    [category_ids] => ,75,76,78,70,82,162,
    [chemical_name] => 
    [weight] => 597.46
    [form] => C30H22Cl2N8O2
    [cas] => NA
    [pslug] => 1-4-bis-8-chloro-5-nitroso-5h-dibenzo-b-e-1-4-diazepin-11-yl-piperazine-pa030721011
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PA 03 0721011

1,4-bis(8-Chloro-5-nitroso-5H-dibenzo[b,e][1,4]diazepin-11-yl)piperazine


  • Catalogue No.:PA 03 0721011

  • CAS :

    NA

  • Molecular Formula : C30H22Cl2N8O2

  • Molecular Weight : 597.46