Atogepant-impurities | Pharmaffiliates

Atogepant

Atogepant is under investigation in clinical trial NCT03855137 (Efficacy, Safety, and Tolerability of Atogepant for the Prevention of Chronic Migraine). Reference standards of Atogepant API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Atogepant - API Standards 
    [catalogue_number] => PA 01 3310000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 603.53
    [form] => C29H23F6N5O3
    [cas] => 1374248-81-3
    [pslug] => 1374248-81-3-atogepant-api-pa013310000
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PA 01 3310000

Atogepant - API Standards


  • Catalogue No.:PA 01 3310000

  • CAS :

    1374248-81-3

  • Molecular Formula : C29H23F6N5O3

  • Molecular Weight : 603.53

stdClass Object
(
    [pname] => Tert-butyl ((5S,6R)-6-methyl-2-oxo-5-(2,3,6-trifluorophenyl)piperidin-3-yl)carbamate
    [catalogue_number] => PA 01 3311000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 358.36
    [form] => C17H21F3N2O3
    [cas] => 1456803-42-1
    [pslug] => 1456803-42-1-tert-butyl-5s-6r-6-methyl-2-oxo-5-2-3-6-trifluorophenyl-piperidin-3-yl-carbamate-pa013311000
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PA 01 3311000

Tert-butyl ((5S,6R)-6-methyl-2-oxo-5-(2,3,6-trifluorophenyl)piperidin-3-yl)carbamate


  • Catalogue No.:PA 01 3311000

  • CAS :

    1456803-42-1

  • Molecular Formula : C17H21F3N2O3

  • Molecular Weight : 358.36

stdClass Object
(
    [pname] => Isopropyl 2-((tert-butoxycarbonyl)amino)-5-oxo-4-(2,3,6-trifluorophenyl)hexanoate
    [catalogue_number] => PA 01 3311001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 417.43
    [form] => C20H26F3NO5
    [cas] => 1488326-89-1
    [pslug] => 1488326-89-1-isopropyl-2-tert-butoxycarbonyl-amino-5-oxo-4-2-3-6-trifluorophenyl-hexanoate-pa013311001
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PA 01 3311001

Isopropyl 2-((tert-butoxycarbonyl)amino)-5-oxo-4-(2,3,6-trifluorophenyl)hexanoate


  • Catalogue No.:PA 01 3311001

  • CAS :

    1488326-89-1

  • Molecular Formula : C20H26F3NO5

  • Molecular Weight : 417.43

stdClass Object
(
    [pname] => rel-(3′R)-1′,2′,5,7-Tetrahydro-N-[(3R,5R,6S)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-2′-oxospiro[6H-cyclopenta[b]pyridine-6,3′-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide
    [catalogue_number] => PA 01 3311002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 603.53
    [form] => C29H23F6N5O3
    [cas] => 2733814-47-4
    [pslug] => 2733814-47-4-rel-3r-1-2-5-7-tetrahydro-n-3r-5r-6s-6-methyl-2-oxo-1-2-2-2-trifluoroethyl-5-2-3-6-trifluorophenyl-3-piperidinyl-2-oxospiro-6h-cyclopenta-b-pyridine-6-3-3h-pyrrolo-2-3-b-pyridine-3-carboxamide-pa013311002
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PA 01 3311002

rel-(3′R)-1′,2′,5,7-Tetrahydro-N-[(3R,5R,6S)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)-3-piperidinyl]-2′-oxospiro[6H-cyclopenta[b]pyridine-6,3′-[3H]pyrrolo[2,3-b]pyridine]-3-carboxamide


  • Catalogue No.:PA 01 3311002

  • CAS :

    2733814-47-4

  • Molecular Formula : C29H23F6N5O3

  • Molecular Weight : 603.53

stdClass Object
(
    [pname] => N-((3S,5S,6R)-6-Methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)acetamide
    [catalogue_number] => PA 01 3311003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 382.31
    [form] => C16H16F6N2O2
    [cas] => NA
    [pslug] => n-3s-5s-6r-6-methyl-2-oxo-1-2-2-2-trifluoroethyl-5-2-3-6-trifluorophenyl-piperidin-3-yl-acetamide-pa013311003
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PA 01 3311003

N-((3S,5S,6R)-6-Methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)acetamide


  • Catalogue No.:PA 01 3311003

  • CAS :

    NA

  • Molecular Formula : C16H16F6N2O2

  • Molecular Weight : 382.31

stdClass Object
(
    [pname] => (S)-2'-Oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylic Acid
    [catalogue_number] => PA 01 3311004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 281.27
    [form] => C15H11N3O3
    [cas] => 1375541-21-1
    [pslug] => 1375541-21-1-s-2-oxo-1-2-5-7-tetrahydrospiro-cyclopenta-b-pyridine-6-3-pyrrolo-2-3-b-pyridine-3-carboxylic-acid-pa013311004
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PA 01 3311004

(S)-2'-Oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylic Acid


  • Catalogue No.:PA 01 3311004

  • CAS :

    1375541-21-1

  • Molecular Formula : C15H11N3O3

  • Molecular Weight : 281.27

stdClass Object
(
    [pname] => (S)-2-Acetamido-N-((3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-3-phenylpropanamide
    [catalogue_number] => PA 01 3311005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 529.48
    [form] => C25H25F6N3O3
    [cas] => NA
    [pslug] => s-2-acetamido-n-3s-5s-6r-6-methyl-2-oxo-1-2-2-2-trifluoroethyl-5-2-3-6-trifluorophenyl-piperidin-3-yl-3-phenylpropanamide-pa013311005
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PA 01 3311005

(S)-2-Acetamido-N-((3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-3-phenylpropanamide


  • Catalogue No.:PA 01 3311005

  • CAS :

    NA

  • Molecular Formula : C25H25F6N3O3

  • Molecular Weight : 529.48

stdClass Object
(
    [pname] => (3S,5S,6R)-3-Amino-6-methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-2-one
    [catalogue_number] => PA 01 3311006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 340.27
    [form] => C14H14F6N2O
    [cas] => 1375794-72-1
    [pslug] => 1375794-72-1-3s-5s-6r-3-amino-6-methyl-1-2-2-2-trifluoroethyl-5-2-3-6-trifluorophenyl-piperidin-2-one-pa013311006
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PA 01 3311006

(3S,5S,6R)-3-Amino-6-methyl-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-2-one


  • Catalogue No.:PA 01 3311006

  • CAS :

    1375794-72-1

  • Molecular Formula : C14H14F6N2O

  • Molecular Weight : 340.27

stdClass Object
(
    [pname] => (S)-N-((3S,5S,6R)-6-Methyl-2-oxo-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
    [catalogue_number] => PA 01 3311007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 521.5
    [form] => C27H22F3N5O3
    [cas] => NA
    [pslug] => s-n-3s-5s-6r-6-methyl-2-oxo-5-2-3-6-trifluorophenyl-piperidin-3-yl-2-oxo-1-2-5-7-tetrahydrospiro-cyclopenta-b-pyridine-6-3-pyrrolo-2-3-b-pyridine-3-carboxamide-pa013311007
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PA 01 3311007

(S)-N-((3S,5S,6R)-6-Methyl-2-oxo-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide


  • Catalogue No.:PA 01 3311007

  • CAS :

    NA

  • Molecular Formula : C27H22F3N5O3

  • Molecular Weight : 521.5

stdClass Object
(
    [pname] => Methyl (S)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylate
    [catalogue_number] => PA 01 3311008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 295.3
    [form] => C16H13N3O3
    [cas] => NA
    [pslug] => methyl-s-2-oxo-1-2-5-7-tetrahydrospiro-cyclopenta-b-pyridine-6-3-pyrrolo-2-3-b-pyridine-3-carboxylate-pa013311008
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PA 01 3311008

Methyl (S)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxylate


  • Catalogue No.:PA 01 3311008

  • CAS :

    NA

  • Molecular Formula : C16H13N3O3

  • Molecular Weight : 295.3

stdClass Object
(
    [pname] => (S)-N-((3R,5S,6R)-6-Methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
    [catalogue_number] => PA 01 3311009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 603.53
    [form] => C29H23F6N5O3
    [cas] => NA
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PA 01 3311009

(S)-N-((3R,5S,6R)-6-Methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide


  • Catalogue No.:PA 01 3311009

  • CAS :

    NA

  • Molecular Formula : C29H23F6N5O3

  • Molecular Weight : 603.53

stdClass Object
(
    [pname] => (S)-N-((3S,5S,6S)-6-Methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
    [catalogue_number] => PA 01 3311010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 603.53
    [form] => C29H23F6N5O3
    [cas] => NA
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PA 01 3311010

(S)-N-((3S,5S,6S)-6-Methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl)-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide


  • Catalogue No.:PA 01 3311010

  • CAS :

    NA

  • Molecular Formula : C29H23F6N5O3

  • Molecular Weight : 603.53