Lotilaner

Pharmaceutical standards - Lotilaner, sold under the brand name Xdemvy. It is an ectoparasiticide medication. It is an antiparasitic agent used to treat Demodex blepharitis. Reference standards of Lotilaner API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Lotilaner
    [catalogue_number] => PA 12 2130000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 596.75
    [form] => C20H14Cl3F6N3O3S
    [cas] => 1369852-71-0
    [pslug] => 1369852-71-0-lotilaner-api-standards-pa122130000
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PA 12 2130000
PA 12 2130000

Lotilaner


  • Catalogue No.:PA 12 2130000

  • CAS :

    1369852-71-0

  • Molecular Formula : C20H14Cl3F6N3O3S

  • Molecular Weight : 596.75

stdClass Object
(
    [pname] => Lotilaner R-Isomer
    [catalogue_number] => PA 12 2131000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 596.75
    [form] => C20H14Cl3F6N3O3S
    [cas] => 1369853-98-4
    [pslug] => 1369853-98-4-lotilaner-r-isomer-pa122131000
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PA 12 2131000
PA 12 2131000

Lotilaner R-Isomer


  • Catalogue No.:PA 12 2131000

  • CAS :

    1369853-98-4

  • Molecular Formula : C20H14Cl3F6N3O3S

  • Molecular Weight : 596.75

stdClass Object
(
    [pname] => (S)-3-Methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylic Acid
    [catalogue_number] => PA 12 2131001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 458.66
    [form] => C16H9Cl3F3NO3S
    [cas] => 1918956-01-0
    [pslug] => 1918956-01-0-s-3-methyl-5-5-3-4-5-trichlorophenyl-5-trifluoromethyl-4-5-dihydroisoxazol-3-yl-thiophene-2-carboxylic-acid-pa122131001
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PA 12 2131001
PA 12 2131001

(S)-3-Methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylic Acid


  • Catalogue No.:PA 12 2131001

  • CAS :

    1918956-01-0

  • Molecular Formula : C16H9Cl3F3NO3S

  • Molecular Weight : 458.66

stdClass Object
(
    [pname] => (S)-3-Methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxamide
    [catalogue_number] => PA 12 2131002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 457.67
    [form] => C16H10Cl3F3N2O2S
    [cas] => NA
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PA 12 2131002
PA 12 2131002

(S)-3-Methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxamide


  • Catalogue No.:PA 12 2131002

  • CAS :

    NA

  • Molecular Formula : C16H10Cl3F3N2O2S

  • Molecular Weight : 457.67

stdClass Object
(
    [pname] => (S)-3-(5-Bromo-4-methylthiophen-2-yl)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole
    [catalogue_number] => PA 12 2131003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 493.54
    [form] => C15H8BrCl3F3NOS
    [cas] => 1613733-75-7
    [pslug] => 1613733-75-7-s-3-5-bromo-4-methylthiophen-2-yl-5-3-4-5-trichlorophenyl-5-trifluoromethyl-4-5-dihydroisoxazole-pa122131003
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PA 12 2131003
PA 12 2131003

(S)-3-(5-Bromo-4-methylthiophen-2-yl)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole


  • Catalogue No.:PA 12 2131003

  • CAS :

    1613733-75-7

  • Molecular Formula : C15H8BrCl3F3NOS

  • Molecular Weight : 493.54

stdClass Object
(
    [pname] => (R)-3-(5-Bromo-4-methylthiophen-2-yl)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole
    [catalogue_number] => PA 12 2131004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 493.54
    [form] => C15H8BrCl3F3NOS
    [cas] => 1613733-77-9
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PA 12 2131004
PA 12 2131004

(R)-3-(5-Bromo-4-methylthiophen-2-yl)-5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazole


  • Catalogue No.:PA 12 2131004

  • CAS :

    1613733-77-9

  • Molecular Formula : C15H8BrCl3F3NOS

  • Molecular Weight : 493.54

stdClass Object
(
    [pname] => Methyl (S)-3-methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylate
    [catalogue_number] => PA 12 2131005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 472.68
    [form] => C17H11Cl3F3NO3S
    [cas] => 2758907-90-1
    [pslug] => 2758907-90-1-methyl-s-3-methyl-5-5-3-4-5-trichlorophenyl-5-trifluoromethyl-4-5-dihydroisoxazol-3-yl-thiophene-2-carboxylate-pa122131005
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PA 12 2131005
PA 12 2131005

Methyl (S)-3-methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylate


  • Catalogue No.:PA 12 2131005

  • CAS :

    2758907-90-1

  • Molecular Formula : C17H11Cl3F3NO3S

  • Molecular Weight : 472.68

stdClass Object
(
    [pname] => Methyl (Z)-3-methyl-5-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl)thiophene-2-carboxylate
    [catalogue_number] => PA 12 2131006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 457.67
    [form] => C17H10Cl3F3O3S
    [cas] => 2758907-89-8
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PA 12 2131006
PA 12 2131006

Methyl (Z)-3-methyl-5-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl)thiophene-2-carboxylate


  • Catalogue No.:PA 12 2131006

  • CAS :

    2758907-89-8

  • Molecular Formula : C17H10Cl3F3O3S

  • Molecular Weight : 457.67

stdClass Object
(
    [pname] => Methyl (E)-3-methyl-5-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl)thiophene-2-carboxylate
    [catalogue_number] => PA 12 2131007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 457.67
    [form] => C17H10Cl3F3O3S
    [cas] => 2758907-88-7
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PA 12 2131007
PA 12 2131007

Methyl (E)-3-methyl-5-(4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)but-2-enoyl)thiophene-2-carboxylate


  • Catalogue No.:PA 12 2131007

  • CAS :

    2758907-88-7

  • Molecular Formula : C17H10Cl3F3O3S

  • Molecular Weight : 457.67

stdClass Object
(
    [pname] => Ethyl 3-methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylate
    [catalogue_number] => PA 12 2131008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 486.71
    [form] => C18H13Cl3F3NO3S
    [cas] => NA
    [pslug] => ethyl-3-methyl-5-5-3-4-5-trichlorophenyl-5-trifluoromethyl-4-5-dihydroisoxazol-3-yl-thiophene-2-carboxylate-pa122131008
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PA 12 2131008
PA 12 2131008

Ethyl 3-methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylate


  • Catalogue No.:PA 12 2131008

  • CAS :

    NA

  • Molecular Formula : C18H13Cl3F3NO3S

  • Molecular Weight : 486.71

stdClass Object
(
    [pname] => 2,2,2-Trifluoro-1-(2,3,5-trichlorophenyl)ethan-1-one
    [catalogue_number] => PA 12 2131009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 277.45
    [form] => C8H2Cl3F3O
    [cas] => 1823321-19-2
    [pslug] => 1823321-19-2-2-2-2-trifluoro-1-2-3-5-trichlorophenyl-ethan-1-one-pa122131009
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PA 12 2131009
PA 12 2131009

2,2,2-Trifluoro-1-(2,3,5-trichlorophenyl)ethan-1-one


  • Catalogue No.:PA 12 2131009

  • CAS :

    1823321-19-2

  • Molecular Formula : C8H2Cl3F3O

  • Molecular Weight : 277.45

stdClass Object
(
    [pname] => 1-(3-Bromo-4,5-dichlorophenyl)-2,2,2-trifluoroethan-1-one
    [catalogue_number] => PA 12 2131010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 321.9
    [form] => C8H2BrCl2F3O
    [cas] => 2226274-70-8
    [pslug] => 2226274-70-8-1-3-bromo-4-5-dichlorophenyl-2-2-2-trifluoroethan-1-one-pa122131010
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PA 12 2131010
PA 12 2131010

1-(3-Bromo-4,5-dichlorophenyl)-2,2,2-trifluoroethan-1-one


  • Catalogue No.:PA 12 2131010

  • CAS :

    2226274-70-8

  • Molecular Formula : C8H2BrCl2F3O

  • Molecular Weight : 321.9

stdClass Object
(
    [pname] => 1,1'-(4,5-Dichloro-1,3-phenylene)bis(2,2,2-trifluoroethan-1-one)
    [catalogue_number] => PA 12 2131011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 339.01
    [form] => C10H2Cl2F6O2
    [cas] => NA
    [pslug] => 1-1-4-5-dichloro-1-3-phenylene-bis-2-2-2-trifluoroethan-1-one-pa122131011
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PA 12 2131011
PA 12 2131011

1,1'-(4,5-Dichloro-1,3-phenylene)bis(2,2,2-trifluoroethan-1-one)


  • Catalogue No.:PA 12 2131011

  • CAS :

    NA

  • Molecular Formula : C10H2Cl2F6O2

  • Molecular Weight : 339.01

stdClass Object
(
    [pname] => Methyl 4-acetyl-5-methylthiophene-2-carboxylate
    [catalogue_number] => PA 12 2131012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 198.24
    [form] => C9H10O3S
    [cas] => 116368-65-1
    [pslug] => 116368-65-1-methyl-4-acetyl-5-methylthiophene-2-carboxylate-pa122131012
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PA 12 2131012
PA 12 2131012

Methyl 4-acetyl-5-methylthiophene-2-carboxylate


  • Catalogue No.:PA 12 2131012

  • CAS :

    116368-65-1

  • Molecular Formula : C9H10O3S

  • Molecular Weight : 198.24

stdClass Object
(
    [pname] => 1,1'-(3-Methylthiophene-2,5-diyl)bis(ethan-1-one)
    [catalogue_number] => PA 12 2131013
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 182.24
    [form] => C9H10O2S
    [cas] => 1303946-86-2
    [pslug] => 1303946-86-2-1-1-3-methylthiophene-2-5-diyl-bis-ethan-1-one-pa122131013
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PA 12 2131013
PA 12 2131013

1,1'-(3-Methylthiophene-2,5-diyl)bis(ethan-1-one)


  • Catalogue No.:PA 12 2131013

  • CAS :

    1303946-86-2

  • Molecular Formula : C9H10O2S

  • Molecular Weight : 182.24

stdClass Object
(
    [pname] => Dimethyl 3-methylthiophene-2,5-dicarboxylate
    [catalogue_number] => PA 12 2131014
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 214.24
    [form] => C9H10O4S
    [cas] => 63762-45-8
    [pslug] => 63762-45-8-dimethyl-3-methylthiophene-2-5-dicarboxylate-pa122131014
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PA 12 2131014
PA 12 2131014

Dimethyl 3-methylthiophene-2,5-dicarboxylate


  • Catalogue No.:PA 12 2131014

  • CAS :

    63762-45-8

  • Molecular Formula : C9H10O4S

  • Molecular Weight : 214.24

stdClass Object
(
    [pname] => 3-Methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylic Acid
    [catalogue_number] => PA 12 2131015
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 458.66
    [form] => C16H9Cl3F3NO3S
    [cas] => 1613733-74-6
    [pslug] => 1613733-74-6-3-methyl-5-5-3-4-5-trichlorophenyl-5-trifluoromethyl-4-5-dihydroisoxazol-3-yl-thiophene-2-carboxylic-acid-pa122131015
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PA 12 2131015
PA 12 2131015

3-Methyl-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxylic Acid


  • Catalogue No.:PA 12 2131015

  • CAS :

    1613733-74-6

  • Molecular Formula : C16H9Cl3F3NO3S

  • Molecular Weight : 458.66

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