Solifenacin-impurities | Pharmaffiliates

solifenacin

A muscarinic receptor antagonist drug used for treating contraction of overactive bladder such as incontinence, urinary frequency, and urgency. Solifenacin is a competitive cholinergic receptor antagonist, selective for the M3 receptor subtype. It was manufactured and marketed by Astellas, GlaxoSmithKline and Teva Pharmaceutical Industries. Reference standards of Solifenacin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => cis-Hydroxy Solifenacin-d5 N-Oxide
(Mixture of Diastereomers)
    [catalogue_number] => PA STI 051630
    [category_ids] => ,69,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 399.49
    [form] => C23H21D5N2O4
    [cas] => NA
    [pslug] => cis-hydroxy-solifenacin-d5-n-oxide
-mixture-of-diastereomers-pasti051630
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PA STI 051630

cis-Hydroxy Solifenacin-d5 N-Oxide (Mixture of Diastereomers)


  • Catalogue No.:PA STI 051630

  • CAS :

    NA

  • Molecular Formula : C23H21D5N2O4

  • Molecular Weight : 399.49

stdClass Object
(
    [pname] => 4R-Hydroxy Solifenacin
    [catalogue_number] => PA 19 0501000
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 378.47
    [form] => C23H26N2O3
    [cas] => 861998-77-8
    [pslug] => 861998-77-8-4r-hydroxy-solifenacin-pa190501000
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PA 19 0501000

4R-Hydroxy Solifenacin


  • Catalogue No.:PA 19 0501000

  • CAS :

    861998-77-8

  • Molecular Formula : C23H26N2O3

  • Molecular Weight : 378.47

stdClass Object
(
    [pname] => (1S,3R,4S)-Quinuclidin-3-yl (1S,4R)-4-hydroxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
    [catalogue_number] => PA 19 0501001
    [category_ids] => ,78,75,70,76,82,
    [chemical_name] => 
    [weight] => 378.47
    [form] => C23H26N2O3
    [cas] => NA
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PA 19 0501001

(1S,3R,4S)-Quinuclidin-3-yl (1S,4R)-4-hydroxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate


  • Catalogue No.:PA 19 0501001

  • CAS :

    NA

  • Molecular Formula : C23H26N2O3

  • Molecular Weight : 378.47

stdClass Object
(
    [pname] => Solifenacin Identification Mixture A
    [catalogue_number] => PA 19 0501004
    [category_ids] => ,80,71,76,75,93,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
    [pslug] => solifenacin-identification-mixture-a-pa190501004
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PA 19 0501004

Solifenacin Identification Mixture A


  • Catalogue No.:PA 19 0501004

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] => Solifenacin Identification Mixture B
    [catalogue_number] => PA 19 0501003
    [category_ids] => ,80,71,76,75,93,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
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PA 19 0501003

Solifenacin Identification Mixture B


  • Catalogue No.:PA 19 0501003

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] => (1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarbonyl chloride
    [catalogue_number] => PA 19 0501005
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 271.74
    [form] => C16H14ClNO
    [cas] => 1195949-26-8
    [pslug] => 1195949-26-8-1s-3-4-dihydro-1-phenyl-2-1h-isoquinolinecarbonyl-chloride-pa190501005
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PA 19 0501005

(1S)-3,4-Dihydro-1-phenyl-2(1H)-isoquinolinecarbonyl chloride


  • Catalogue No.:PA 19 0501005

  • CAS :

    1195949-26-8

  • Molecular Formula : C16H14ClNO

  • Molecular Weight : 271.74

stdClass Object
(
    [pname] => Methyl (S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
    [catalogue_number] => PA 19 0501006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 267.33
    [form] => C17H17NO2
    [cas] => 1251905-45-9
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PA 19 0501006

Methyl (S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate


  • Catalogue No.:PA 19 0501006

  • CAS :

    1251905-45-9

  • Molecular Formula : C17H17NO2

  • Molecular Weight : 267.33

stdClass Object
(
    [pname] => Ethyl (R)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
    [catalogue_number] => PA 19 0501007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 281.36
    [form] => C18H19NO2
    [cas] => 180468-41-1
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PA 19 0501007

Ethyl (R)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate


  • Catalogue No.:PA 19 0501007

  • CAS :

    180468-41-1

  • Molecular Formula : C18H19NO2

  • Molecular Weight : 281.36

stdClass Object
(
    [pname] => (R)-Quinuclidin-3-yl (S)-1-hydroxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
    [catalogue_number] => PA 19 0501008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 378.47
    [form] => C23H26N2O3
    [cas] => NA
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PA 19 0501008

(R)-Quinuclidin-3-yl (S)-1-hydroxy-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate


  • Catalogue No.:PA 19 0501008

  • CAS :

    NA

  • Molecular Formula : C23H26N2O3

  • Molecular Weight : 378.47

stdClass Object
(
    [pname] => Solifenacin Succinate (IPRS/82/19) - from IPC
    [catalogue_number] => PA IPRS 82 19
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
    [pslug] => solifenacin-succinate-iprs-82-19-from-ipc-paiprs8219
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PA IPRS 82 19

Solifenacin Succinate (IPRS/82/19) - from IPC


  • Catalogue No.:PA IPRS 82 19

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] => Quinuclidin-3-one
    [catalogue_number] => PA 19 0501009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 125.17
    [form] => C7H11NO
    [cas] => 3731-38-2
    [pslug] => 3731-38-2-quinuclidin-3-one-pa190501009
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PA 19 0501009

Quinuclidin-3-one


  • Catalogue No.:PA 19 0501009

  • CAS :

    3731-38-2

  • Molecular Formula : C7H11NO

  • Molecular Weight : 125.17

stdClass Object
(
    [pname] => Quinuclidin-3-yl 1-phenyl-3,4-Dihydroisoquinoline-2(1H)-Carboxylate Succinate
    [catalogue_number] => PA 19 0501010
    [category_ids] => 82,78,76,75,70
    [chemical_name] => 
    [weight] => 480.56
    [form] => C27H32N2O6
    [cas] => 2518398-14-4
    [pslug] => 2518398-14-4-quinuclidin-3-yl-1-phenyl-3-4-dihydroisoquinoline-2-1h-carboxylate-succinate-pa190501010
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PA 19 0501010

Quinuclidin-3-yl 1-phenyl-3,4-Dihydroisoquinoline-2(1H)-Carboxylate Succinate


  • Catalogue No.:PA 19 0501010

  • CAS :

    2518398-14-4

  • Molecular Formula : C27H32N2O6

  • Molecular Weight : 480.56

stdClass Object
(
    [pname] => Solifenacin Nitrophenyl Ester Impurity
    [catalogue_number] => PA 19 0501011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 374.4
    [form] => C22H18N2O4
    [cas] => 1229227-22-8
    [pslug] => 1229227-22-8-solifenacin nitrophenyl-ester-impurity-pa190501011
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PA 19 0501011

Solifenacin Nitrophenyl Ester Impurity


  • Catalogue No.:PA 19 0501011

  • CAS :

    1229227-22-8

  • Molecular Formula : C22H18N2O4

  • Molecular Weight : 374.4

stdClass Object
(
    [pname] => Solifenacin - API Standards 
    [catalogue_number] => PA 19 2090000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 362.47
    [form] => C23H26N2O2
    [cas] => 242478-37-1
    [pslug] => 242478-37-1-solifenacin-api-pa192090000
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PA 19 2090000

Solifenacin - API Standards


  • Catalogue No.:PA 19 2090000

  • CAS :

    242478-37-1

  • Molecular Formula : C23H26N2O2

  • Molecular Weight : 362.47

stdClass Object
(
    [pname] => (2R,3R)-2-Ethylquinuclidin-3-yl (S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate
    [catalogue_number] => PA 19 2091000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 390.53
    [form] => C25H30N2O2
    [cas] => 2407763-27-1
    [pslug] => 2407763-27-1-2r-3r-2-ethylquinuclidin-3-yl-s-1-phenyl-3-4-dihydroisoquinoline-2-1h-carboxylate-pa192091000
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PA 19 2091000

(2R,3R)-2-Ethylquinuclidin-3-yl (S)-1-phenyl-3,4-dihydroisoquinoline-2(1H)-carboxylate


  • Catalogue No.:PA 19 2091000

  • CAS :

    2407763-27-1

  • Molecular Formula : C25H30N2O2

  • Molecular Weight : 390.53

stdClass Object
(
    [pname] => 2-Nitroso-1-phenyl-1,2,3,4-tetrahydroisoquinoline
    [catalogue_number] => PA 19 2091001
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 238.29
    [form] => C15H14N2O
    [cas] => 2659259-64-8
    [pslug] => 2659259-64-8-2-nitroso-1-phenyl-1-2-3-4-tetrahydroisoquinoline-pa192091001
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PA 19 2091001

2-Nitroso-1-phenyl-1,2,3,4-tetrahydroisoquinoline


  • Catalogue No.:PA 19 2091001

  • CAS :

    2659259-64-8

  • Molecular Formula : C15H14N2O

  • Molecular Weight : 238.29

stdClass Object
(
    [pname] => (R)-Quinuclidin-3-yl acetate (2R,3R)-2,3-dihydroxysuccinate
    [catalogue_number] => PA 19 2091004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 319.31
    [form] => C13H21NO8
    [cas] => 139729-83-2
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PA 19 2091004

(R)-Quinuclidin-3-yl acetate (2R,3R)-2,3-dihydroxysuccinate


  • Catalogue No.:PA 19 2091004

  • CAS :

    139729-83-2

  • Molecular Formula : C13H21NO8

  • Molecular Weight : 319.31

stdClass Object
(
    [pname] => (R)-4-Nitrophenyl quinuclidin-3-yl carbonate
    [catalogue_number] => PA 19 2091005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 292.29
    [form] => C14H16N2O5
    [cas] => 1243274-81-8
    [pslug] => 1243274-81-8-r-4-nitrophenyl-quinuclidin-3-yl-carbonate-pa192091005
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PA 19 2091005

(R)-4-Nitrophenyl quinuclidin-3-yl carbonate


  • Catalogue No.:PA 19 2091005

  • CAS :

    1243274-81-8

  • Molecular Formula : C14H16N2O5

  • Molecular Weight : 292.29