Simvastatin-impurities | Pharmaffiliates

simvastatin

Simvastatin is used along with exercise, diet, and weight loss to decrease elevated lipid levels. Simvastatin, marketed under the trade name Zocor. It is available as a generic medication.Reference standards of Simvastatin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

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    [pname] => Simvastatin - Impurity A (Sodium Salt)
    [catalogue_number] => PA 19 11010
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    [weight] => 458.56
    [form] => C25H39NaO6
    [cas] => 101314-97-0
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PA 19 11010

Simvastatin - Impurity A (Sodium Salt)


  • Catalogue No.:PA 19 11010

  • CAS :

    101314-97-0

  • Molecular Formula : C25H39NaO6

  • Molecular Weight : 458.56

stdClass Object
(
    [pname] => Simvastatin - Impurity A (Ammonium Salt)
    [catalogue_number] => PA 19 11540
    [category_ids] => 82,78,76,75,70,69,71
    [chemical_name] => 
    [weight] => 453.61
    [form] => C25H43NO6
    [cas] => 139893-43-9
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PA 19 11540

Simvastatin - Impurity A (Ammonium Salt)


  • Catalogue No.:PA 19 11540

  • CAS :

    139893-43-9

  • Molecular Formula : C25H43NO6

  • Molecular Weight : 453.61

stdClass Object
(
    [pname] => Simvastatin Glycerol Ester
    [catalogue_number] => PA 19 11530
    [category_ids] => ,69,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 510.66
    [form] => C28H46O8
    [cas] => NA
    [pslug] => simvastatin-glycerol-ester-pa1911530
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PA 19 11530

Simvastatin Glycerol Ester


  • Catalogue No.:PA 19 11530

  • CAS :

    NA

  • Molecular Formula : C28H46O8

  • Molecular Weight : 510.66

stdClass Object
(
    [pname] => Anhydro Simvastatin Acid Sodium Salt
    [catalogue_number] => PA 19 11550
    [category_ids] => ,69,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 440.55
    [form] => C25H37NaO5
    [cas] => 393825-04-2
    [pslug] => 393825-04-2-anhydro-simvastatin-acid-sodium-salt-pa1911550
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PA 19 11550

Anhydro Simvastatin Acid Sodium Salt


  • Catalogue No.:PA 19 11550

  • CAS :

    393825-04-2

  • Molecular Formula : C25H37NaO5

  • Molecular Weight : 440.55

stdClass Object
(
    [pname] => 6'-Carboxy Simvastatin-d6
    [catalogue_number] => PA STI 017900
    [category_ids] => ,69,71,76,75,78,70,82,98,
    [chemical_name] => 
    [weight] => 454.59
    [form] => C25H30D6O7
    [cas] => 1346604-34-9
    [pslug] => 1346604-34-9-6-carboxy-simvastatin-d6-pasti017900
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PA STI 017900

6'-Carboxy Simvastatin-d6


  • Catalogue No.:PA STI 017900

  • CAS :

    1346604-34-9

  • Molecular Formula : C25H30D6O7

  • Molecular Weight : 454.59

stdClass Object
(
    [pname] => 3',5'-Dihydrodiol Simvastatin-d6
(Mixture of Diastereomers)
    [catalogue_number] => PA STI 032770
    [category_ids] => ,69,70,71,75,76,78,82,98,
    [chemical_name] => 
    [weight] => 458.62
    [form] => C25H34D6O7
    [cas] => NA
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PA STI 032770

3',5'-Dihydrodiol Simvastatin-d6 (Mixture of Diastereomers)


  • Catalogue No.:PA STI 032770

  • CAS :

    NA

  • Molecular Formula : C25H34D6O7

  • Molecular Weight : 458.62

stdClass Object
(
    [pname] => Simvastatin-d6 Hydroxy Acid Sodium Salt
    [catalogue_number] => PA STI 079290
    [category_ids] => ,69,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 465.61
    [form] => C25H33D6NaO6
    [cas] => NA
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PA STI 079290

Simvastatin-d6 Hydroxy Acid Sodium Salt


  • Catalogue No.:PA STI 079290

  • CAS :

    NA

  • Molecular Formula : C25H33D6NaO6

  • Molecular Weight : 465.61

stdClass Object
(
    [pname] => Simvastatin-d6 Hydroxy Acid Ammonium Salt
    [catalogue_number] => PA STI 079310
    [category_ids] => ,69,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 459.65
    [form] => C25H37D6NO6
    [cas] => NA
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PA STI 079310

Simvastatin-d6 Hydroxy Acid Ammonium Salt


  • Catalogue No.:PA STI 079310

  • CAS :

    NA

  • Molecular Formula : C25H37D6NO6

  • Molecular Weight : 459.65

stdClass Object
(
    [pname] => Simvastatin - Impurity J
    [catalogue_number] => PA 19 11100
    [category_ids] => ,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 432.60
    [form] => C26H40O5
    [cas] => 864357-88-0
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PA 19 11100

Simvastatin - Impurity J


  • Catalogue No.:PA 19 11100

  • CAS :

    864357-88-0

  • Molecular Formula : C26H40O5

  • Molecular Weight : 432.60

stdClass Object
(
    [pname] => (1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-((tert-Butyldimethylsilyl)oxy)-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl isobutyrate
    [catalogue_number] => PAI 19 001691
    [category_ids] => ,75,76,70,78,82,
    [chemical_name] => 
    [weight] => 504.78
    [form] => C29H48O5Si
    [cas] => NA
    [pslug] => -1s-3r-7s-8s-8ar-8-2-2r-4r-4-tert-butyldimethylsilyl-oxy-6-oxotetrahydro-2h-pyran-2-yl-ethyl-3-7-dimethyl-1-2-3-7-8-8a-hexahydronaphthalen-1-yl-isobutyrate-pai19001691
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PAI 19 001691

(1S,3R,7S,8S,8aR)-8-(2-((2R,4R)-4-((tert-Butyldimethylsilyl)oxy)-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl isobutyrate


  • Catalogue No.:PAI 19 001691

  • CAS :

    NA

  • Molecular Formula : C29H48O5Si

  • Molecular Weight : 504.78

stdClass Object
(
    [pname] => (4S)-Hydroxy Simvastatin
    [catalogue_number] => PA 19 0111000
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 434.57
    [form] => C25H38O6
    [cas] => 149949-05-3
    [pslug] => 149949-05-3-4s-hydroxy-simvastatin-pa190111000
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PA 19 0111000

(4S)-Hydroxy Simvastatin


  • Catalogue No.:PA 19 0111000

  • CAS :

    149949-05-3

  • Molecular Formula : C25H38O6

  • Molecular Weight : 434.57

stdClass Object
(
    [pname] => 6-Oxo Simvastatin
    [catalogue_number] => PA 19 0111001
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 432.56
    [form] => C25H36O6
    [cas] => 130468-11-0
    [pslug] => 130468-11-0-6-oxo-simvastatin-pa190111001
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PA 19 0111001

6-Oxo Simvastatin


  • Catalogue No.:PA 19 0111001

  • CAS :

    130468-11-0

  • Molecular Formula : C25H36O6

  • Molecular Weight : 432.56

stdClass Object
(
    [pname] => (3R)-Hydroxperoxy Simvastatin
    [catalogue_number] => PA 19 0111002
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 450.57
    [form] => C25H38O7
    [cas] => 1092716-42-1
    [pslug] => 1092716-42-1-3r-hydroxperoxy-simvastatin-pa190111002
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PA 19 0111002

(3R)-Hydroxperoxy Simvastatin


  • Catalogue No.:PA 19 0111002

  • CAS :

    1092716-42-1

  • Molecular Formula : C25H38O7

  • Molecular Weight : 450.57

stdClass Object
(
    [pname] => 3”-Hydroxy simvastatin
    [catalogue_number] => PA 19 0111003
    [category_ids] => ,69,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 434.57
    [form] => C25H38O6
    [cas] => 126313-98-2
    [pslug] => 126313-98-2-3-hydroxy-simvastatin-pa190111003
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PA 19 0111003

3”-Hydroxy simvastatin


  • Catalogue No.:PA 19 0111003

  • CAS :

    126313-98-2

  • Molecular Formula : C25H38O6

  • Molecular Weight : 434.57

stdClass Object
(
    [pname] => 3”-Hydroxy simvastatin acid sodium salt
    [catalogue_number] => PA 19 0111004
    [category_ids] => ,69,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 474.57
    [form] => C25H39NaO7
    [cas] => 1316302-95-0
    [pslug] => 1316302-95-0-3-hydroxy-simvastatin-acid-sodium-salt-pa190111004
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PA 19 0111004

3”-Hydroxy simvastatin acid sodium salt


  • Catalogue No.:PA 19 0111004

  • CAS :

    1316302-95-0

  • Molecular Formula : C25H39NaO7

  • Molecular Weight : 474.57

stdClass Object
(
    [pname] => 6’-Hydroxymethyl simvastatin
    [catalogue_number] => PA 19 0111005
    [category_ids] => ,69,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 434.57
    [form] => C25H38O6
    [cas] => 114883-29-3
    [pslug] => 114883-29-3-6-hydroxymethyl-simvastatin-pa190111005
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PA 19 0111005

6’-Hydroxymethyl simvastatin


  • Catalogue No.:PA 19 0111005

  • CAS :

    114883-29-3

  • Molecular Formula : C25H38O6

  • Molecular Weight : 434.57

stdClass Object
(
    [pname] => 6’-Exomethylene Simvastatin
    [catalogue_number] => PA 19 0111006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 416.56
    [form] => C25H36O5
    [cas] => 121624-18-8
    [pslug] => 121624-18-8-6-exomethylene-simvastatin-pa190111006
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PA 19 0111006

6’-Exomethylene Simvastatin


  • Catalogue No.:PA 19 0111006

  • CAS :

    121624-18-8

  • Molecular Formula : C25H36O5

  • Molecular Weight : 416.56

stdClass Object
(
    [pname] => Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether
    [catalogue_number] => PA 19 0111007
    [category_ids] => ,69,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 434.69
    [form] => C25H42O4Si
    [cas] => 79902-31-1
    [pslug] => 79902-31-1-lovastatin-diol-lactone-4-tert-butyldimethylsilyl-ether-pa190111007
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PA 19 0111007

Lovastatin Diol Lactone 4-tert-Butyldimethylsilyl Ether


  • Catalogue No.:PA 19 0111007

  • CAS :

    79902-31-1

  • Molecular Formula : C25H42O4Si

  • Molecular Weight : 434.69

stdClass Object
(
    [pname] => (1aS,2R,3S,3aR,4S,6R,7bR)-3-(2-((2S,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-2,6-dimethyl-1a,2,3,3a,4,5,6,7b-octahydronaphtho[1,2-b]oxiren-4-yl 2,2-dimethylbutanoate compound with (1aS,2R,5S,6S,8aR)-5-(2-((2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-2,6-dimethyl-1a,2,4,4a,5,6-hexahydro-3H-naphtho[1,8a-b]oxiren-4-yl 2,2-dimethylbutanoate (1:1)
    [catalogue_number] => PAI 19 001690
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 869.15
    [form] => C50H76O12
    [cas] => NA
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PAI 19 001690

(1aS,2R,3S,3aR,4S,6R,7bR)-3-(2-((2S,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-2,6-dimethyl-1a,2,3,3a,4,5,6,7b-octahydronaphtho[1,2-b]oxiren-4-yl 2,2-dimethylbutanoate compound with (1aS,2R,5S,6S,8aR)-5-(2-((2S,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-2,6-dimethyl-1a,2,4,4a,5,6-hexahydro-3H-naphtho[1,8a-b]oxiren-4-yl 2,2-dimethylbutanoate (1:1)


  • Catalogue No.:PAI 19 001690

  • CAS :

    NA

  • Molecular Formula : C50H76O12

  • Molecular Weight : 869.15

stdClass Object
(
    [pname] => Des(2-methylbutyryl) lovastatin hydroxy acid sodium salt
    [catalogue_number] => PA 19 0111008
    [category_ids] => ,69,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 360.43
    [form] => C19H29NaO5
    [cas] => 132294-94-1
    [pslug] => 132294-94-1-des-2-methylbutyryl-lovastatin-hydroxy-acid-sodium-salt-pa190111008
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PA 19 0111008

Des(2-methylbutyryl) lovastatin hydroxy acid sodium salt


  • Catalogue No.:PA 19 0111008

  • CAS :

    132294-94-1

  • Molecular Formula : C19H29NaO5

  • Molecular Weight : 360.43

stdClass Object
(
    [pname] => 6’-Carboxy simvastatin
    [catalogue_number] => PA 19 0111009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 448.56
    [form] => C25H36O7
    [cas] => 114883-30-6
    [pslug] => 114883-30-6-6-carboxy-simvastatin-pa190111009
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PA 19 0111009

6’-Carboxy simvastatin


  • Catalogue No.:PA 19 0111009

  • CAS :

    114883-30-6

  • Molecular Formula : C25H36O7

  • Molecular Weight : 448.56

stdClass Object
(
    [pname] => 3’(S)-Hydroxy simvastatin
    [catalogue_number] => PA 19 0111010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 434.57
    [form] => C25H38O6
    [cas] => 133645-46-2
    [pslug] => 133645-46-2-3-s-hydroxy-simvastatin-pa190111010
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PA 19 0111010

3’(S)-Hydroxy simvastatin


  • Catalogue No.:PA 19 0111010

  • CAS :

    133645-46-2

  • Molecular Formula : C25H38O6

  • Molecular Weight : 434.57

stdClass Object
(
    [pname] => Simvastatin, 1-Pyreneacetyl Ester
    [catalogue_number] => PA 19 0111011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 678.87
    [form] => C43H50O7
    [cas] => 193682-18-7
    [pslug] => 193682-18-7-simvastatin-1-pyreneacetyl-ester-pa190111011
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PA 19 0111011

Simvastatin, 1-Pyreneacetyl Ester


  • Catalogue No.:PA 19 0111011

  • CAS :

    193682-18-7

  • Molecular Formula : C43H50O7

  • Molecular Weight : 678.87

stdClass Object
(
    [pname] => Simvastatin Acyl-ß-D-glucuronide
    [catalogue_number] => PA 19 0111012
    [category_ids] => ,70,75,76,78,82,95,
    [chemical_name] => 
    [weight] => 612.71
    [form] => C31H48O12
    [cas] => 463962-56-3
    [pslug] => 463962-56-3-simvastatin-acyl-beta-d-glucuronide-pa190111012
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PA 19 0111012

Simvastatin Acyl-ß-D-glucuronide


  • Catalogue No.:PA 19 0111012

  • CAS :

    463962-56-3

  • Molecular Formula : C31H48O12

  • Molecular Weight : 612.71

stdClass Object
(
    [pname] => 4a’,6’-Anhydro-4-tert-butyldimethylsilyl Simvastatin
    [catalogue_number] => PA 19 0111013
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 548.84
    [form] => C31H52O6Si
    [cas] => 125175-64-6
    [pslug] => 125175-64-6-4a-6-anhydro-4-tert-butyldimethylsilyl-simvastatin-pa190111013
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PA 19 0111013

4a’,6’-Anhydro-4-tert-butyldimethylsilyl Simvastatin


  • Catalogue No.:PA 19 0111013

  • CAS :

    125175-64-6

  • Molecular Formula : C31H52O6Si

  • Molecular Weight : 548.84

stdClass Object
(
    [pname] => 4-tert-Butyldimethylsilyl-4a’-hydroxy Simvastatin
    [catalogue_number] => PA 19 0111014
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 550.85
    [form] => C31H54O6Si
    [cas] => 125142-16-7
    [pslug] => 125142-16-7-4-tert-butyldimethylsilyl-4a-hydroxy-simvastatin-pa190111014
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PA 19 0111014

4-tert-Butyldimethylsilyl-4a’-hydroxy Simvastatin


  • Catalogue No.:PA 19 0111014

  • CAS :

    125142-16-7

  • Molecular Formula : C31H54O6Si

  • Molecular Weight : 550.85

stdClass Object
(
    [pname] => 4-tert-Butyldimethylsilyl-5'-chloro-4a'-hydroxy simvastatin
    [catalogue_number] => PA 19 0111015
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 585.29
    [form] => C31H53ClO6Si
    [cas] => 123852-10-8
    [pslug] => 123852-10-8-4-tert-butyldimethylsilyl-5-chloro-4a-hydroxy-simvastatin-pa190111015
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PA 19 0111015

4-tert-Butyldimethylsilyl-5'-chloro-4a'-hydroxy simvastatin


  • Catalogue No.:PA 19 0111015

  • CAS :

    123852-10-8

  • Molecular Formula : C31H53ClO6Si

  • Molecular Weight : 585.29

stdClass Object
(
    [pname] => (1S,3R,7S,8S,8aR)-3,7-Dimethyl-8-(2-((R)-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl)-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (R)-2-methylbutanoate
    [catalogue_number] => PAI 19 001692
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 386.53
    [form] => C24H34O4
    [cas] => NA
    [pslug] => 1s-3r-7s-8s-8ar-3-7-dimethyl-8-2-r-6-oxo-3-6-dihydro-2h-pyran-2-yl-ethyl-1-2-3-7-8-8a-hexahydronaphthalen-1-yl-r-2-methylbutanoate-pai19001692
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PAI 19 001692

(1S,3R,7S,8S,8aR)-3,7-Dimethyl-8-(2-((R)-6-oxo-3,6-dihydro-2H-pyran-2-yl)ethyl)-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (R)-2-methylbutanoate


  • Catalogue No.:PAI 19 001692

  • CAS :

    NA

  • Molecular Formula : C24H34O4

  • Molecular Weight : 386.53

stdClass Object
(
    [pname] => (1S,3S,7S,8S,8aS)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyldecahydronaphthalen-1-yl 2,2-dimethylbutanoate
    [catalogue_number] => PA 19 11620
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 422.61
    [form] => C25H42O5
    [cas] => 87770-13-6
    [pslug] => 87770-13-6-1s-3s-7s-8s-8as-8-2-2r-4r-4-hydroxy-6-oxotetrahydro-2h-pyran-2-yl-ethyl-3-7-dimethyldecahydronaphthalen-1-yl-2-2-dimethylbutanoate-pa1911620
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PA 19 11620

(1S,3S,7S,8S,8aS)-8-(2-((2R,4R)-4-Hydroxy-6-oxotetrahydro-2H-pyran-2-yl)ethyl)-3,7-dimethyldecahydronaphthalen-1-yl 2,2-dimethylbutanoate


  • Catalogue No.:PA 19 11620

  • CAS :

    87770-13-6

  • Molecular Formula : C25H42O5

  • Molecular Weight : 422.61

stdClass Object
(
    [pname] => Simvastatin (IPRS/87/19) -from IPC
    [catalogue_number] => PA IPRS 87 19
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
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PA IPRS 87 19

Simvastatin (IPRS/87/19) -from IPC


  • Catalogue No.:PA IPRS 87 19

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] => 6(S)-Hydroperoxy Simvastatin
    [catalogue_number] => PA 19 0111017
    [category_ids] => ,78,75,76,82,
    [chemical_name] => 
    [weight] => 450.57
    [form] => C25H38O7
    [cas] => 149949-01-9
    [pslug] => 149949-01-9-6-s-hydroperoxy-simvastatin-pa190111017
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PA 19 0111017

6(S)-Hydroperoxy Simvastatin


  • Catalogue No.:PA 19 0111017

  • CAS :

    149949-01-9

  • Molecular Formula : C25H38O7

  • Molecular Weight : 450.57