Saxagliptin-impurities | Pharmaffiliates

saxagliptin

Saxagliptin is used as monotherapy or in combination with other drugs for the treatment of type 2 diabetes. It is an oral hypoglycemic SaxagliptinIt, it is sold under the brand name Onglyza.Reference standards of Saxagliptin API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Hydroxy Saxagliptin-13C3
    [catalogue_number] => PA STI 051620
    [category_ids] => ,79,69,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 334.39
    [form] => C1513C3H25N3O3
    [cas] => 1346597-23-6
    [pslug] => 1346597-23-6-hydroxy-saxagliptin-13c3-pasti051620
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PA STI 051620

Hydroxy Saxagliptin-13C3


  • Catalogue No.:PA STI 051620

  • CAS :

    1346597-23-6

  • Molecular Formula : C1513C3H25N3O3

  • Molecular Weight : 334.39

stdClass Object
(
    [pname] => (1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetic Acid
    [catalogue_number] => PA 19 0401000
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 240.18
    [form] => C8H11F3N2O3
    [cas] => 1133811-50-3
    [pslug] => 1133811-50-3-1r-3r-5r-2-azabicyclo-3-1-0-hexane-3-carboxamide-2-2-2-trifluoroacetic-acid-pa190401000
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PA 19 0401000

(1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetic Acid


  • Catalogue No.:PA 19 0401000

  • CAS :

    1133811-50-3

  • Molecular Formula : C8H11F3N2O3

  • Molecular Weight : 240.18

stdClass Object
(
    [pname] => (1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetic Acid
    [catalogue_number] => PA 19 0401001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 240.18
    [form] => C8H11F3N2O3
    [cas] => 700376-58-5
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PA 19 0401001

(1R,3S,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide 2,2,2-trifluoroacetic Acid


  • Catalogue No.:PA 19 0401001

  • CAS :

    700376-58-5

  • Molecular Formula : C8H11F3N2O3

  • Molecular Weight : 240.18

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    [pname] => (1S,3S,5S)-2-((R)-2-Amino-2-((1r,3S,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride
    [catalogue_number] => PA 19 0401003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 351.88
    [form] => C18H26ClN3O2
    [cas] => NA
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PA 19 0401003

(1S,3S,5S)-2-((R)-2-Amino-2-((1r,3S,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride


  • Catalogue No.:PA 19 0401003

  • CAS :

    NA

  • Molecular Formula : C18H26ClN3O2

  • Molecular Weight : 351.88

stdClass Object
(
    [pname] => (1S,3R,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride
    [catalogue_number] => PA 19 0401004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 351.88
    [form] => C18H26ClN3O2
    [cas] => NA
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PA 19 0401004

(1S,3R,5S)-2-((2S)-2-Amino-2-(3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile hydrochloride


  • Catalogue No.:PA 19 0401004

  • CAS :

    NA

  • Molecular Formula : C18H26ClN3O2

  • Molecular Weight : 351.88

stdClass Object
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    [pname] => Saxagliptin O-Sulfate
    [catalogue_number] => PA 19 0401005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 395.47
    [form] => C18H25N3O5S
    [cas] => 1429782-94-4
    [pslug] => 1429782-94-4-saxagliptin-o-sulfate-pa190401005
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PA 19 0401005

Saxagliptin O-Sulfate


  • Catalogue No.:PA 19 0401005

  • CAS :

    1429782-94-4

  • Molecular Formula : C18H25N3O5S

  • Molecular Weight : 395.47

stdClass Object
(
    [pname] => Saxagliptin N-Carboxybenzyl
    [catalogue_number] => PA 19 0401006
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 449.55
    [form] => C26H31N3O4
    [cas] => 1408335-73-8
    [pslug] => 1408335-73-8-saxagliptin-n-carboxybenzyl-pa190401006
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PA 19 0401006

Saxagliptin N-Carboxybenzyl


  • Catalogue No.:PA 19 0401006

  • CAS :

    1408335-73-8

  • Molecular Formula : C26H31N3O4

  • Molecular Weight : 449.55

stdClass Object
(
    [pname] => (2R,2’R,cis)-Deoxy-saxagliptin
    [catalogue_number] => PA 19 0401007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 299.42
    [form] => C18H25N3O
    [cas] => NA
    [pslug] => 2r-2r-cis-deoxy-saxagliptin-pa190401007
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PA 19 0401007

(2R,2’R,cis)-Deoxy-saxagliptin


  • Catalogue No.:PA 19 0401007

  • CAS :

    NA

  • Molecular Formula : C18H25N3O

  • Molecular Weight : 299.42

stdClass Object
(
    [pname] => (2R,2’R,trans)-Deoxy-saxagliptin
    [catalogue_number] => PA 19 0401008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 299.42
    [form] => C18H25N3O
    [cas] => NA
    [pslug] => 2r-2r-trans-deoxy-saxagliptin-pa190401008
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PA 19 0401008

(2R,2’R,trans)-Deoxy-saxagliptin


  • Catalogue No.:PA 19 0401008

  • CAS :

    NA

  • Molecular Formula : C18H25N3O

  • Molecular Weight : 299.42

stdClass Object
(
    [pname] => (2R,2’S,cis)-Deoxy-saxagliptin
    [catalogue_number] => PA 19 0401009
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 299.42
    [form] =>  C18H25N3O
    [cas] => NA
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PA 19 0401009

(2R,2’S,cis)-Deoxy-saxagliptin


  • Catalogue No.:PA 19 0401009

  • CAS :

    NA

  • Molecular Formula : C18H25N3O

  • Molecular Weight : 299.42

stdClass Object
(
    [pname] => (2S,2’R,cis)-7-Hydroxy-saxagliptin
    [catalogue_number] => PA 19 0401010
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 331.42
    [form] =>  C18H25N3O3
    [cas] => 1795791-40-0
    [pslug] => 1795791-40-0-2s-2r-cis-7-hydroxy-saxagliptin-pa190401010
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PA 19 0401010

(2S,2’R,cis)-7-Hydroxy-saxagliptin


  • Catalogue No.:PA 19 0401010

  • CAS :

    1795791-40-0

  • Molecular Formula : C18H25N3O3

  • Molecular Weight : 331.42

stdClass Object
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    [pname] => (2R,2’R,Trans)-7-Hydroxy-saxagliptin
    [catalogue_number] => PA 19 0401011
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 331.42
    [form] =>  C18H25N3O3
    [cas] => NA
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PA 19 0401011

(2R,2’R,Trans)-7-Hydroxy-saxagliptin


  • Catalogue No.:PA 19 0401011

  • CAS :

    NA

  • Molecular Formula : C18H25N3O3

  • Molecular Weight : 331.42

stdClass Object
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    [pname] => (2S,2’S,Trans)-7-Hydroxy-saxagliptin
    [catalogue_number] => PA 19 0401012
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    [chemical_name] => 
    [weight] => 331.42
    [form] => C18H25N3O3
    [cas] => NA
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PA 19 0401012

(2S,2’S,Trans)-7-Hydroxy-saxagliptin


  • Catalogue No.:PA 19 0401012

  • CAS :

    NA

  • Molecular Formula : C18H25N3O3

  • Molecular Weight : 331.42

stdClass Object
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    [pname] => (2R,2’R,cis)-7-Hydroxy-saxagliptin
    [catalogue_number] => PA 19 0401013
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 331.42
    [form] => C18H25N3O3
    [cas] => 1310011-46-1
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PA 19 0401013

(2R,2’R,cis)-7-Hydroxy-saxagliptin


  • Catalogue No.:PA 19 0401013

  • CAS :

    1310011-46-1

  • Molecular Formula : C18H25N3O3

  • Molecular Weight : 331.42

stdClass Object
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    [pname] => (S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic Acid
    [catalogue_number] => PA 19 0401014
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 241.29
    [form] => C12H19NO4
    [cas] => 178172-26-4
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PA 19 0401014

(S)-1-Boc-2,3-dihydro-2-pyrrolecarboxylic Acid


  • Catalogue No.:PA 19 0401014

  • CAS :

    178172-26-4

  • Molecular Formula : C12H19NO4

  • Molecular Weight : 241.29

stdClass Object
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    [pname] => Nα-Boc-L-Ornithine
    [catalogue_number] => PA 19 0401015
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 232.28
    [form] => C10H20N2O4
    [cas] => 21887-64-9
    [pslug] => 21887-64-9-nalpha-boc-l-ornithine-pa190401015
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PA 19 0401015

Nα-Boc-L-Ornithine


  • Catalogue No.:PA 19 0401015

  • CAS :

    21887-64-9

  • Molecular Formula : C10H20N2O4

  • Molecular Weight : 232.28

stdClass Object
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    [pname] => (1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid
    [catalogue_number] => PA 19 0401016
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 227.26
    [form] => C11H17NO4
    [cas] => 197142-36-2
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PA 19 0401016

(1S,3S,5S)-2-Boc-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid


  • Catalogue No.:PA 19 0401016

  • CAS :

    197142-36-2

  • Molecular Formula : C11H17NO4

  • Molecular Weight : 227.26

stdClass Object
(
    [pname] => (E)-4-(((1S)-2-((1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-((3R,5R,7S)-3-hydroxyadamantan-1-yl)-2-oxoethyl)amino)-4-oxobut-2-enoic acid
    [catalogue_number] => PA 19 0401017
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    [chemical_name] => 
    [weight] => 413.47
    [form] => C22H27N3O5
    [cas] => NA
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PA 19 0401017

(E)-4-(((1S)-2-((1S,3S,5S)-3-Cyano-2-azabicyclo[3.1.0]hexan-2-yl)-1-((3R,5R,7S)-3-hydroxyadamantan-1-yl)-2-oxoethyl)amino)-4-oxobut-2-enoic acid


  • Catalogue No.:PA 19 0401017

  • CAS :

    NA

  • Molecular Formula : C22H27N3O5

  • Molecular Weight : 413.47

stdClass Object
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    [pname] => (1S,3S,5S)-2-((2S)-2-(((3R,4R,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)-2-((3R,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile
    [catalogue_number] => PA 19 0401018
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    [weight] => 639.3
    [form] => C30H45N3O12
    [cas] => NA
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PA 19 0401018

(1S,3S,5S)-2-((2S)-2-(((3R,4R,6R)-3,4-Dihydroxy-6-(hydroxymethyl)-5-(((3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)amino)-2-((3R,5R,7S)-3-hydroxyadamantan-1-yl)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile


  • Catalogue No.:PA 19 0401018

  • CAS :

    NA

  • Molecular Formula : C30H45N3O12

  • Molecular Weight : 639.3

stdClass Object
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    [pname] => (1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide
    [catalogue_number] => PA 19 0401019
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 126.16
    [form] => C6H10N2O
    [cas] => 1133811-49-0
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PA 19 0401019

(1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide


  • Catalogue No.:PA 19 0401019

  • CAS :

    1133811-49-0

  • Molecular Formula : C6H10N2O

  • Molecular Weight : 126.16

stdClass Object
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    [pname] => (1S,3R,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide
    [catalogue_number] => PA 19 0401020
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    [chemical_name] => 
    [weight] => 126.16
    [form] => C6H10N2O
    [cas] => 1564266-73-4
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PA 19 0401020

(1S,3R,5S)-2-Azabicyclo[3.1.0]hexane-3-carboxamide


  • Catalogue No.:PA 19 0401020

  • CAS :

    1564266-73-4

  • Molecular Formula : C6H10N2O

  • Molecular Weight : 126.16

stdClass Object
(
    [pname] => 3-Hydroxyadamantane-1-carboxylic acid
    [catalogue_number] => PA 19 0401021
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 196.25
    [form] => C11H16O3
    [cas] => 42711-75-1
    [pslug] => 42711-75-1-3-hydroxyadamantane-1-carboxylic-acid-pa190401021
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PA 19 0401021

3-Hydroxyadamantane-1-carboxylic acid


  • Catalogue No.:PA 19 0401021

  • CAS :

    42711-75-1

  • Molecular Formula : C11H16O3

  • Molecular Weight : 196.25

stdClass Object
(
    [pname] => (1R, 3S, 5S, 2'R)-Saxagliptin
    [catalogue_number] => PA 19 0401022
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 315.42
    [form] => C18H25N3O2
    [cas] => NA
    [pslug] => 1r-3s-5s-2r-saxagliptin-pa190401022
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PA 19 0401022

(1R, 3S, 5S, 2'R)-Saxagliptin


  • Catalogue No.:PA 19 0401022

  • CAS :

    NA

  • Molecular Formula : C18H25N3O2

  • Molecular Weight : 315.42

stdClass Object
(
    [pname] => (1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate
    [catalogue_number] => PA 19 0401023
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 222.26
    [form] => C7H14N2O4S
    [cas] => 1312338-82-1
    [pslug] => 1312338-82-1-1r-3r-5r-2-azabicyclo-3-1-0-hexane-3-carboxamide-methanesulfonate-pa190401023
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PA 19 0401023

(1R,3R,5R)-2-Azabicyclo[3.1.0]hexane-3-carboxamide Methanesulfonate


  • Catalogue No.:PA 19 0401023

  • CAS :

    1312338-82-1

  • Molecular Formula : C7H14N2O4S

  • Molecular Weight : 222.26

stdClass Object
(
    [pname] => (1R,3R,5R)-2-Nitroso-2-azabicyclo[3.1.0]hexane-3-carbonitrile
    [catalogue_number] => PA 19 0401024
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 137.14
    [form] => C6H7N3O
    [cas] => NA
    [pslug] => 1r-3r-5r-2-nitroso-2-azabicyclo-3-1-0-hexane-3-carbonitrile-pa190401024
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PA 19 0401024

(1R,3R,5R)-2-Nitroso-2-azabicyclo[3.1.0]hexane-3-carbonitrile


  • Catalogue No.:PA 19 0401024

  • CAS :

    NA

  • Molecular Formula : C6H7N3O

  • Molecular Weight : 137.14

stdClass Object
(
    [pname] => (1R,3S,5R)-2-((2S)-2-(3-Hydroxyadamantan-1-yl)-2-(tritylamino)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile
    [catalogue_number] => PA 19 0401026
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 557.74
    [form] => C37H39N3O2
    [cas] => NA
    [pslug] => 1r-3s-5r-2-2s-2-3-hydroxyadamantan-1-yl-2-tritylamino-acetyl-2-azabicyclo-3-1-0-hexane-3-carbonitrile-pa190401026
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PA 19 0401026

(1R,3S,5R)-2-((2S)-2-(3-Hydroxyadamantan-1-yl)-2-(tritylamino)acetyl)-2-azabicyclo[3.1.0]hexane-3-carbonitrile


  • Catalogue No.:PA 19 0401026

  • CAS :

    NA

  • Molecular Formula : C37H39N3O2

  • Molecular Weight : 557.74

stdClass Object
(
    [pname] => (1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid
    [catalogue_number] => PA 19 0401025
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 227.26
    [form] => C11H17NO4
    [cas] => 197142-34-0
    [pslug] => 197142-34-0-1r-3s-5r-2-tert-butoxycarbonyl-2-azabicyclo-3-1-0-hexane-3-carboxylic-acid-pa190401025
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PA 19 0401025

(1R,3S,5R)-2-(tert-Butoxycarbonyl)-2-azabicyclo[3.1.0]hexane-3-carboxylic Acid


  • Catalogue No.:PA 19 0401025

  • CAS :

    197142-34-0

  • Molecular Formula : C11H17NO4

  • Molecular Weight : 227.26

stdClass Object
(
    [pname] => (S)-2-((3S,5S,7S)-Adamantan-1-yl)-2-(((R)-2-hydroxy-1-phenylethyl)amino)acetonitrile
    [catalogue_number] => PA 19 0401027
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 310.44
    [form] => C20H26N2O
    [cas] => 361441-95-4
    [pslug] => 361441-95-4-s-2-3s-5s-7s-adamantan-1-yl-2-r-2-hydroxy-1-phenylethyl-amino-acetonitrile-pa190401027
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PA 19 0401027

(S)-2-((3S,5S,7S)-Adamantan-1-yl)-2-(((R)-2-hydroxy-1-phenylethyl)amino)acetonitrile


  • Catalogue No.:PA 19 0401027

  • CAS :

    361441-95-4

  • Molecular Formula : C20H26N2O

  • Molecular Weight : 310.44