An antihypertensive drug, Sacubitril Isopropylamine is used in combination with valsartan for the treatment of heart ailments. A prodrug of sacubitrilat which is an inhibitor of enzyme neprilysin, which aids the degradation of blood pressure-lowering peptides, atrial and brain natriuretic peptide. Reference standards of Sacubitril Isopropylamine API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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