Pralsetinib
Pralsetinib, sold under the brand name Gavreto, is a medication approved RET mutation-positive medullary thyroid cancer and RET fusion-positive differentiated thyroid cancer refractory to radioactive iodine therapy. Reference standards of Pralsetinib API, and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.
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[pname] => Pralsetinib
[catalogue_number] => PA 16 3770000
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[chemical_name] =>
[weight] => 533.61
[form] => C27H32FN9O2
[cas] => 2097132-94-8
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Catalogue No.:PA 16 3770000
Molecular Formula : C27H32FN9O2
Molecular Weight : 533.61
stdClass Object
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[pname] => (S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine Hydrochloride
[catalogue_number] => PA 16 3771000
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[chemical_name] =>
[weight] => 242.68
[form] => C10H12ClFN4
[cas] => 2097133-17-8
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(S)-1-(6-(4-Fluoro-1H-pyrazol-1-yl)pyridin-3-yl)ethan-1-amine Hydrochloride
Catalogue No.:PA 16 3771000
Molecular Formula : C10H12ClFN4
Molecular Weight : 242.68
stdClass Object
(
[pname] => Methyl cis-1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]cyclohexanecarboxylate
[catalogue_number] => PA 16 3771001
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[chemical_name] =>
[weight] => 359.43
[form] => C18H25N5O3
[cas] => 2778223-51-9
[pslug] => 2778223-51-9-methyl cis-1-methoxy-4-4-methyl-6-5-methyl-1h-pyrazol-3-yl-amino-2-pyrimidinyl-cyclohexanecarboxylate-pa163771001
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Methyl cis-1-methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]cyclohexanecarboxylate
Catalogue No.:PA 16 3771001
Molecular Formula : C18H25N5O3
Molecular Weight : 359.43
stdClass Object
(
[pname] => cis-1-Methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]cyclohexanecarboxylic Acid
[catalogue_number] => PA 16 3771002
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[chemical_name] =>
[weight] => 345.4
[form] => C17H23N5O3
[cas] => 2778223-52-0
[pslug] => 2778223-52-0-cis-1-methoxy-4-4-methyl-6-5-methyl-1h-pyrazol-3-yl-amino-2-pyrimidinyl-cyclohexanecarboxylic-acid-pa163771002
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cis-1-Methoxy-4-[4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-2-pyrimidinyl]cyclohexanecarboxylic Acid