olanzapine

Metabolites - A dopamine antagonist , that belongs to the class of thienobenzodiazepine. Olanzapine is used in treatment of schizophrenia and bipolar disorder. An atypical antipsychotic drug.Reference standards of Olanzapine API,and its pharmacopeial, non pharmacopeial impurities, and stable isotopes are listed below.

stdClass Object
(
    [pname] => Olanzapine
    [catalogue_number] => PA 15 03000
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 312.43
    [form] => C17H20N4S
    [cas] => 132539-06-1
    [pslug] => 132539-06-1-olanzapine-api-pa1503000
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PA 15 03000
PA 15 03000

Olanzapine


  • Catalogue No.:PA 15 03000

  • CAS :

    132539-06-1

  • Molecular Formula : C17H20N4S

  • Molecular Weight : 312.43

stdClass Object
(
    [pname] => Olanzapine - Impurity B
    [catalogue_number] => PA 15 03020
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 230.29
    [form] => C12H10N2OS
    [cas] => 221176-49-4
    [pslug] => 221176-49-4-olanzapine-impurity-b-freebase-pa1503020
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PA 15 03020
PA 15 03020

Olanzapine - Impurity B


  • Catalogue No.:PA 15 03020

  • CAS :

    221176-49-4

  • Molecular Formula : C12H10N2OS

  • Molecular Weight : 230.29

stdClass Object
(
    [pname] => Olanzapine - Impurity D
    [catalogue_number] => PA 15 03040
    [category_ids] => ,70,71,75,76,78,82,88,
    [chemical_name] => 
    [weight] => 328.43
    [form] => C17H20N4OS
    [cas] => 174794-02-6
    [pslug] => 174794-02-6-olanzapine-impurity-d-pa1503040
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PA 15 03040
PA 15 03040

Olanzapine - Impurity D


  • Catalogue No.:PA 15 03040

  • CAS :

    174794-02-6

  • Molecular Formula : C17H20N4OS

  • Molecular Weight : 328.43

stdClass Object
(
    [pname] => N-Demethyl Olanzapine
    [catalogue_number] => PA 15 03520
    [category_ids] => ,76,
    [chemical_name] => 
    [weight] => 298.41
    [form] => C16H18N4S
    [cas] => 161696-76-0
    [pslug] => 161696-76-0-n-demethyl-olanzapine-pa1503520
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PA 15 03520
PA 15 03520

N-Demethyl Olanzapine


  • Catalogue No.:PA 15 03520

  • CAS :

    161696-76-0

  • Molecular Formula : C16H18N4S

  • Molecular Weight : 298.41

stdClass Object
(
    [pname] => 2-Hydroxymethyl Olanzapine
    [catalogue_number] => PA 15 03590
    [category_ids] => ,71,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 328.43
    [form] => C17H20N4OS
    [cas] => 174756-45-7
    [pslug] => 174756-45-7-2-hydroxymethyl-olanzapine-pa1503590
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PA 15 03590
PA 15 03590

2-Hydroxymethyl Olanzapine


  • Catalogue No.:PA 15 03590

  • CAS :

    174756-45-7

  • Molecular Formula : C17H20N4OS

  • Molecular Weight : 328.43

stdClass Object
(
    [pname] => 2-Methyl-10-(2-nitrophenyl)-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine
    [catalogue_number] => PA 15 03600
    [category_ids] => ,80,71,76,75,78,70,82,88,79,
    [chemical_name] => 
    [weight] => 350.39
    [form] => C18H14N4O2S
    [cas] =>  2985926-30-3
    [pslug] => 2985926-30-3-2-methyl-10-2-nitrophenyl-10h-benzo-b-thieno-2-3-e-1-4-diazepin-4-amine-pa1503600
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PA 15 03600
PA 15 03600

2-Methyl-10-(2-nitrophenyl)-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-amine


  • Catalogue No.:PA 15 03600

  • CAS :

     2985926-30-3

  • Molecular Formula : C18H14N4O2S

  • Molecular Weight : 350.39

stdClass Object
(
    [pname] => N-Demethyl Olanzapine-d8
    [catalogue_number] => PA STI 025670
    [category_ids] => ,76,98,
    [chemical_name] => 
    [weight] => 306.46
    [form] => C16H10D8N4S
    [cas] => 786686-82-6
    [pslug] => 786686-82-6-n-demethyl-olanzapine-d8-pasti025670
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PA STI 025670
PA STI 025670

N-Demethyl Olanzapine-d8


  • Catalogue No.:PA STI 025670

  • CAS :

    786686-82-6

  • Molecular Formula : C16H10D8N4S

  • Molecular Weight : 306.46

stdClass Object
(
    [pname] => cis-10-Hydroxy Nortriptyline-D3
    [catalogue_number] => PA STI 050020
    [category_ids] => ,71,98,76,75,78,70,82,
    [chemical_name] => 
    [weight] => 282.39
    [form] => C19H18D3NO
    [cas] => NA
    [pslug] => cis-10-hydroxy-nortriptyline-d3-pasti050020
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PA STI 050020
PA STI 050020

cis-10-Hydroxy Nortriptyline-D3


  • Catalogue No.:PA STI 050020

  • CAS :

    NA

  • Molecular Formula : C19H18D3NO

  • Molecular Weight : 282.39

stdClass Object
(
    [pname] => Olanzapine-d3 N-Oxide
    [catalogue_number] => PA STI 088776
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 331.45
    [form] => C17H17D3N4OS
    [cas] => 1189732-75-9
    [pslug] => 1189732-75-9-olanzapine-d3-n-oxide-pasti088776
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PA STI 088776
PA STI 088776

Olanzapine-d3 N-Oxide


  • Catalogue No.:PA STI 088776

  • CAS :

    1189732-75-9

  • Molecular Formula : C17H17D3N4OS

  • Molecular Weight : 331.45

stdClass Object
(
    [pname] => 2-Hydroxymethyl Olanzapine-d3 (Major)
    [catalogue_number] => PA STI 088777
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 331.45
    [form] => C17H17D3N4OS
    [cas] => 1190006-36-0
    [pslug] => 1190006-36-0-2-hydroxymethyl-olanzapine-d3-major-pasti088777
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PA STI 088777
PA STI 088777

2-Hydroxymethyl Olanzapine-d3 (Major)


  • Catalogue No.:PA STI 088777

  • CAS :

    1190006-36-0

  • Molecular Formula : C17H17D3N4OS

  • Molecular Weight : 331.45

stdClass Object
(
    [pname] => 2,2'-Dimethyl-[10,10'-bibenzo[b]thieno[2,3-e][1,4]diazepine]-4,4'-diamine
    [catalogue_number] => PA 15 0820001
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 456.59
    [form] => C24H20N6S2
    [cas] => NA
    [pslug] => 2-2-dimethyl-10-10-bibenzo-b-thieno-2-3-e-1-4-diazepine-4-4-diamine-pa150820001
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PA 15 0820001
PA 15 0820001

2,2'-Dimethyl-[10,10'-bibenzo[b]thieno[2,3-e][1,4]diazepine]-4,4'-diamine


  • Catalogue No.:PA 15 0820001

  • CAS :

    NA

  • Molecular Formula : C24H20N6S2

  • Molecular Weight : 456.59

stdClass Object
(
    [pname] => 2-Methyl-N10-(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine-4,10-diamine
    [catalogue_number] => PA 15 0820002
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 456.59
    [form] => C24H20N6S2
    [cas] => NA
    [pslug] => 2-methyl-n10-2-methyl-10h-benzo-b-thieno-2-3-e-1-4-diazepin-4-yl-10h-benzo-b-thieno-2-3-e-1-4-diazepine-4-10-diamine-pa150820002
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PA 15 0820002
PA 15 0820002

2-Methyl-N10-(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine-4,10-diamine


  • Catalogue No.:PA 15 0820002

  • CAS :

    NA

  • Molecular Formula : C24H20N6S2

  • Molecular Weight : 456.59

stdClass Object
(
    [pname] => 2-((2-Aminophenyl)amino)-N-(3-cyano-5-methylthiophen-2-yl)-5-methylthiophene-3-carboxamide
    [catalogue_number] => PA 15 0820003
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 368.47
    [form] => C18H16N4OS2
    [cas] => NA
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PA 15 0820003
PA 15 0820003

2-((2-Aminophenyl)amino)-N-(3-cyano-5-methylthiophen-2-yl)-5-methylthiophene-3-carboxamide


  • Catalogue No.:PA 15 0820003

  • CAS :

    NA

  • Molecular Formula : C18H16N4OS2

  • Molecular Weight : 368.47

stdClass Object
(
    [pname] => 1,2-Bis(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)hydrazine
    [catalogue_number] => PA 15 0820004
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 456.59
    [form] => C24H20N6S2
    [cas] => NA
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PA 15 0820004
PA 15 0820004

1,2-Bis(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)hydrazine


  • Catalogue No.:PA 15 0820004

  • CAS :

    NA

  • Molecular Formula : C24H20N6S2

  • Molecular Weight : 456.59

stdClass Object
(
    [pname] => N-Demethyl-N-formylolanzapine
    [catalogue_number] => PA 15 0820005
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 326.42
    [form] => C17H18N4OS
    [cas] => 639460-79-0
    [pslug] => 639460-79-0-n-demethyl-n-formylolanzapine-pa150820005
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PA 15 0820005
PA 15 0820005

N-Demethyl-N-formylolanzapine


  • Catalogue No.:PA 15 0820005

  • CAS :

    639460-79-0

  • Molecular Formula : C17H18N4OS

  • Molecular Weight : 326.42

stdClass Object
(
    [pname] => 1,4-Bis(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)piperazine
    [catalogue_number] => PA 15 0820007
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 510.68
    [form] => C28H26N6S2
    [cas] => 1070876-09-3
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PA 15 0820007
PA 15 0820007

1,4-Bis(2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepin-4-yl)piperazine


  • Catalogue No.:PA 15 0820007

  • CAS :

    1070876-09-3

  • Molecular Formula : C28H26N6S2

  • Molecular Weight : 510.68

stdClass Object
(
    [pname] => 2-Methyl-4-(4-methylpiperazin-1-yl)-10-nitroso-10H-benzo[b]thieno[2,3-e][1,4]diazepine
    [catalogue_number] => PA 15 0820006
    [category_ids] => ,162,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 341.43
    [form] => C17H19N5OS
    [cas] => NA
    [pslug] => 2-methyl-4-4-methylpiperazin-1-yl-10-nitroso-10h-benzo-b-thieno-2-3-e-1-4-diazepine-pa150820006
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PA 15 0820006
PA 15 0820006

2-Methyl-4-(4-methylpiperazin-1-yl)-10-nitroso-10H-benzo[b]thieno[2,3-e][1,4]diazepine


  • Catalogue No.:PA 15 0820006

  • CAS :

    NA

  • Molecular Formula : C17H19N5OS

  • Molecular Weight : 341.43

stdClass Object
(
    [pname] => Olanzapine (IPRS/94/16) - from IPC
    [catalogue_number] => PA IPRS 94 16
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => NA
    [form] => NA
    [cas] => NA
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PA IPRS 94 16
PA IPRS 94 16

Olanzapine (IPRS/94/16) - from IPC


  • Catalogue No.:PA IPRS 94 16

  • CAS :

    NA

  • Molecular Formula : NA

  • Molecular Weight : NA

stdClass Object
(
    [pname] => 2-(bis(2-Nitrophenyl)amino)-5-methylthiophene-3-carbonitrile
    [catalogue_number] => PA 15 0820008
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 380.38
    [form] => C18H12N4O4S
    [cas] => NA
    [pslug] => 2-bis-2-nitrophenyl-amino-5-methylthiophene-3-carbonitrile-pa150820008
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PA 15 0820008
PA 15 0820008

2-(bis(2-Nitrophenyl)amino)-5-methylthiophene-3-carbonitrile


  • Catalogue No.:PA 15 0820008

  • CAS :

    NA

  • Molecular Formula : C18H12N4O4S

  • Molecular Weight : 380.38

stdClass Object
(
    [pname] => 2-Methyl-10-Nitroso-10H-Benzo[b]thieno[2,3-e][1,4]diazepin-4-amine
    [catalogue_number] => PA 15 0820009
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 258.3
    [form] => C12H10N4OS
    [cas] => NA
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PA 15 0820009
PA 15 0820009

2-Methyl-10-Nitroso-10H-Benzo[b]thieno[2,3-e][1,4]diazepin-4-amine


  • Catalogue No.:PA 15 0820009

  • CAS :

    NA

  • Molecular Formula : C12H10N4OS

  • Molecular Weight : 258.3

stdClass Object
(
    [pname] => 2-Methyl-10-nitroso-4-(piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine
    [catalogue_number] => PA 15 0820010
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 327.41
    [form] => C16H17N5OS
    [cas] => NA
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PA 15 0820010
PA 15 0820010

2-Methyl-10-nitroso-4-(piperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine


  • Catalogue No.:PA 15 0820010

  • CAS :

    NA

  • Molecular Formula : C16H17N5OS

  • Molecular Weight : 327.41

stdClass Object
(
    [pname] => 2-Methyl-4-(4-nitrosopiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine
    [catalogue_number] => PA 15 0820011
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 327.41
    [form] => C16H17N5OS
    [cas] => NA
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PA 15 0820011
PA 15 0820011

2-Methyl-4-(4-nitrosopiperazin-1-yl)-10H-benzo[b]thieno[2,3-e][1,4]diazepine


  • Catalogue No.:PA 15 0820011

  • CAS :

    NA

  • Molecular Formula : C16H17N5OS

  • Molecular Weight : 327.41

stdClass Object
(
    [pname] => 4-Ethyl-5-methyl-2-((2-nitrophenyl)amino)isophthalonitrile
    [catalogue_number] => PA 15 0820012
    [category_ids] => ,75,76,78,70,82,
    [chemical_name] => 
    [weight] => 306.33
    [form] => C17H14N4O2
    [cas] => 2554975-45-8
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PA 15 0820012
PA 15 0820012

4-Ethyl-5-methyl-2-((2-nitrophenyl)amino)isophthalonitrile


  • Catalogue No.:PA 15 0820012

  • CAS :

    2554975-45-8

  • Molecular Formula : C17H14N4O2

  • Molecular Weight : 306.33

stdClass Object
(
    [pname] => Olanzapine Thiohydroxymethylidene (E/Z-Mixture)
    [catalogue_number] => PA 15 0820013
    [category_ids] => ,82,78,76,75,70,
    [chemical_name] => 
    [weight] => 302.4
    [form] => C15H18N4OS
    [cas] => 1320360-86-8
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PA 15 0820013
PA 15 0820013

Olanzapine Thiohydroxymethylidene (E/Z-Mixture)


  • Catalogue No.:PA 15 0820013

  • CAS :

    1320360-86-8

  • Molecular Formula : C15H18N4OS

  • Molecular Weight : 302.4

stdClass Object
(
    [pname] => Olanzapine Dimer Impurity
    [catalogue_number] => PA 15 0820015
    [category_ids] => ,76,78,70,82,
    [chemical_name] => 
    [weight] => 524.71
    [form] => C29H28N6S2
    [cas] => NA
    [pslug] => olanzapine-dimer-impurity-pa150820015
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PA 15 0820015
PA 15 0820015

Olanzapine Dimer Impurity


  • Catalogue No.:PA 15 0820015

  • CAS :

    NA

  • Molecular Formula : C29H28N6S2

  • Molecular Weight : 524.71

stdClass Object
(
    [pname] => 4-(4-Ethylpiperazin-1-yl)-2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepine
    [catalogue_number] => PA 15 0820016
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 326.46
    [form] => C18H22N4S
    [cas] => 1797009-17-6
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PA 15 0820016
PA 15 0820016

4-(4-Ethylpiperazin-1-yl)-2-methyl-10H-benzo[b]thieno[2,3-e][1,4]diazepine


  • Catalogue No.:PA 15 0820016

  • CAS :

    1797009-17-6

  • Molecular Formula : C18H22N4S

  • Molecular Weight : 326.46

stdClass Object
(
    [pname] => Olanzapine 10-N-glucuronide
    [catalogue_number] => PA 15 0820017
    [category_ids] => ,70,75,76,78,82,95,
    [chemical_name] => 
    [weight] => 488.56
    [form] => C23H28N4O6S
    [cas] => 186792-80-3
    [pslug] => 186792-80-3-olanzapine-10-n-glucuronide-pa150820017
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PA 15 0820017
PA 15 0820017

Olanzapine 10-N-glucuronide


  • Catalogue No.:PA 15 0820017

  • CAS :

    186792-80-3

  • Molecular Formula : C23H28N4O6S

  • Molecular Weight : 488.56

stdClass Object
(
    [pname] => N-Desmethyl N-Ethyl Olanzapine
    [catalogue_number] => PA 15 0820018
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 326.46
    [form] => C18H22N4S
    [cas] => 1355034-54-6
    [pslug] => 1355034-54-6-n-desmethyl-n-ethyl-olanzapine-pa150820018
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PA 15 0820018
PA 15 0820018

N-Desmethyl N-Ethyl Olanzapine


  • Catalogue No.:PA 15 0820018

  • CAS :

    1355034-54-6

  • Molecular Formula : C18H22N4S

  • Molecular Weight : 326.46

stdClass Object
(
    [pname] => (2-((2-Aminophenyl)amino)-5-methylthiophen-3-yl)(4-methylpiperazin-1-yl)methanone formate
    [catalogue_number] => PA 15 0820019
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 376.48
    [form] => C18H24N4O3S
    [cas] => NA
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PA 15 0820019
PA 15 0820019

(2-((2-Aminophenyl)amino)-5-methylthiophen-3-yl)(4-methylpiperazin-1-yl)methanone formate


  • Catalogue No.:PA 15 0820019

  • CAS :

    NA

  • Molecular Formula : C18H24N4O3S

  • Molecular Weight : 376.48

stdClass Object
(
    [pname] => 2-((2-Aminophenyl)amino)-5-methylthiophene-3-carboxylic Acid
    [catalogue_number] => PA 15 0820020
    [category_ids] => ,70,75,76,78,82,
    [chemical_name] => 
    [weight] => 248.3
    [form] => C12H12N2O2S
    [cas] => 1807606-58-1
    [pslug] => 1807606-58-1-2-2-aminophenyl-amino-5-methylthiophene-3-carboxylic-acid-pa150820020
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PA 15 0820020
PA 15 0820020

2-((2-Aminophenyl)amino)-5-methylthiophene-3-carboxylic Acid


  • Catalogue No.:PA 15 0820020

  • CAS :

    1807606-58-1

  • Molecular Formula : C12H12N2O2S

  • Molecular Weight : 248.3

stdClass Object
(
    [pname] => N-(3-Cyano-5-methylthiophen-2-yl)-N-(2-nitrophenyl)nitrous amide
    [catalogue_number] => PA 15 0820023
    [category_ids] => ,70,75,76,78,82,162,
    [chemical_name] => 
    [weight] => 288.28
    [form] => C12H8N4O3S
    [cas] => NA
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PA 15 0820023
PA 15 0820023

N-(3-Cyano-5-methylthiophen-2-yl)-N-(2-nitrophenyl)nitrous amide


  • Catalogue No.:PA 15 0820023

  • CAS :

    NA

  • Molecular Formula : C12H8N4O3S

  • Molecular Weight : 288.28

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